Orbitofrontal Cortex: Prediction and Evaluation of Behavioral Outcomes

The orbitofrontal cortex has long been associated with concepts like impulsivity, self-control, and emotion regulation. Here we review recent work that is starting to overturn these ideas and instead indicates that OFC provides predictions about specific outcomes associated with stimuli, choices, and actions, especially their moment-to-moment value based on current internal states. For more information, see Rudebeck & Murray in Neuron 84(6), www.cell.com/ne....

[@inactive4316]

This guy is my uncle no joke

[@tristinroberts5598]

anterior OFC appears to signal expected sensation of certain stimuli
posterior ofc appears to signal expected sensory consequences of preplanned activities
just taking notes on the video for my self. no need to worry about this unless you want to comment and have a discussion about neuroanatomy

[@trav-c137]

I'm a pot user. I've read that pot can shrink the OFC. I want to get a brain scan but I'm afraid of the radiation. thoughts?

[@necroduel3998]

An fMRI doesn't use radioactive isotopes to image. It uses electromagnetism, hense the name Magnetic Resonance Imaging. Completely harmless.

[@kantiannambo]

I need help. With a Full PET investigating the Lesions and Malformations in my CNS. USN Disabled Veteran.

[@hollya.g.86]

I hope you found a good neurologist/neuropsych Joell

[@blakedior7203]

Can some one dumb it down a little thanks.

[@perceptionshare2248]

Well explained. Thanks for sharing.

[@suewoo5]

This was an excellent explanation. Youd have to look up all known localized functions of the brain then presict what functions are conducive to sensory predictions and then test those activity levels in the brain before during and after performing a task or gross locomotion

[@thisisTrev]

Amazing. Do you have any thoughts on its influence on speech?
I'm chasing stuttering.

[@JamzYamz7]

Can an orbital floor fracture cause this?

[@hollya.g.86]

the orbitofrontal cortex is on the other side of the eye, closer to the orbital roof. any head injury can cause diffuse damage to the axons of neurons from sheer shock, or the brain hitting the skull during head trauma. you can always try to get a referral to a neurologist if you're worried or experiencing symptoms that weren't present before the injury. an MRI would probably show damage if there was any