Molecular docking | Introduction to basic computational chemistry method | drug-target interaction

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  • Опубликовано: 11 дек 2024

Комментарии • 46

  • @scienceaddicted3431
    @scienceaddicted3431  4 года назад +14

    I hope this video is useful for you. Please let me know if you have suggestions, ideas, or need for some of the next videos topics. Thanks for visiting the channel. Let's keep the discussions going!

    • @BasicScienceSeries
      @BasicScienceSeries 4 года назад +2

      Indeed! Let's support and take the science to everyone around the globe free of cost! Looking forward to seeing more videos. Thanks!

    • @scienceaddicted3431
      @scienceaddicted3431  4 года назад

      Thanks you for the support! Due to my day job, my time and energy is very limited, but I'm working on the script for the next video! Can't wait to have it finalized!

  • @screechza
    @screechza 3 месяца назад

    going bald tryna understand this by myself. Shoutout to my kowalski buddy for showing me your vid!

  • @fatineaissani7123
    @fatineaissani7123 3 года назад +1

    Thank you for the simple explanation

  • @thedigitalchemist5757
    @thedigitalchemist5757 2 года назад

    thank you , the video is very useful after watching this video things started to become clear for me.

  • @ahmedboshaala6849
    @ahmedboshaala6849 9 месяцев назад

    Thank you , very good information.

  • @sadidmorshed8363
    @sadidmorshed8363 3 года назад

    This is literally Helpful.Thanks a lot for sharing ❤️🥰

  • @rashamoustafa427
    @rashamoustafa427 Год назад

    Great lecture 👌 😊❤❤

  • @RehanKhanPRK
    @RehanKhanPRK 3 года назад +2

    Very informative video 👍 Thanks

    • @scienceaddicted3431
      @scienceaddicted3431  3 года назад

      Thank you for the encouraging comment! Glad the vide was useful

  • @screechza
    @screechza 3 месяца назад

    anyway, what's your thought on the new SwissDock with AC2?

  • @chandanaranga
    @chandanaranga 4 года назад +1

    Simple and precise...good information 👍

    • @scienceaddicted3431
      @scienceaddicted3431  4 года назад +1

      Thank you so much for watching. I'm glad you found it useful.

    • @chandanaranga
      @chandanaranga 4 года назад +1

      @@scienceaddicted3431 keep doing such videos...they are really informative...I was searching for docking videos but haven't found a single one which is precise and simple...but yours really given a quick insight into the topic

    • @scienceaddicted3431
      @scienceaddicted3431  4 года назад +2

      @@chandanaranga That is really nice to hear and will certainly motivate me to finish the video about practical tips in docking. This method appears to be simple and accessible, but there are many ways to mess it up and get artifacts without realizing

  • @BasicScienceSeries
    @BasicScienceSeries 4 года назад

    *Valuable information! Thank you.*

  • @benjaminewilliamcordez5195
    @benjaminewilliamcordez5195 3 года назад

    Thank you for this!

  • @saptantoputra7937
    @saptantoputra7937 3 года назад +2

    Searching suitable key for specific lock 🔐 using algorithm and scoring

  • @br353
    @br353 2 года назад +1

    Thanks you

  • @نرجسمحرمی
    @نرجسمحرمی 3 месяца назад

    How can I download these animations for my presentation

  • @samuelaina4861
    @samuelaina4861 7 месяцев назад

    Hi,
    I'm from Nigeria, I will like to learn more about computational chemistry at large can you render any help towards this?

  • @Myri912
    @Myri912 3 года назад +2

    Great video, a curiosity...what is the program have you use for the slides? thanks so much

    • @scienceaddicted3431
      @scienceaddicted3431  3 года назад +1

      Thank you! I have used kdenlive video editor and animation to create this.

  • @mahamafzal8108
    @mahamafzal8108 3 года назад +1

    Hi ..can u answer me few confusion..
    I took protein id from pdb database but it in their is no Ligand present in it..
    How we know to docked particular ligand with protein..
    Please get me out of confusion...

    • @scienceaddicted3431
      @scienceaddicted3431  3 года назад +2

      Hi! You can check multiple structures in pdb, to see if there is any with ligand included. There is an Advanced Search option, where you can filter and refine your search. In case you don't know the binding site on a protein, there is a docking technique called blind docking, where you can search and scan for binding sites on the entire surface of a protein.

    • @scienceaddicted3431
      @scienceaddicted3431  3 года назад +2

      Thanks for watching and let me know if my answer clarified your confusion!

  • @ximenaramirezvelasco7139
    @ximenaramirezvelasco7139 Год назад

    ❤❤❤❤❤

  • @محمدالداهري-ز7ق
    @محمدالداهري-ز7ق Год назад

    hi , i need for he[p in molecule docking can you help me please

  • @agila19
    @agila19 Год назад

    which software is used to find small molecule-small molecule binding interaction...?

    • @scienceaddicted3431
      @scienceaddicted3431  Год назад

      Hi Agila, there are many, but I most frequently used autodock and autodock vina

    • @agila19
      @agila19 Год назад

      @@scienceaddicted3431 thanks, but autodock is used to find the binding between macromolecules + no of small molecules right..?

  •  2 года назад +2

    Hey there! What's your name? I am using your video for my undergrad presentation (with credits) and I'd like to cite your name and educational background =) Thank you

    • @scienceaddicted3431
      @scienceaddicted3431  2 года назад +1

      Hello Ursula! That is amazing, thank you! Also happy that i was able to help in any way. Please email me at Science.addicted at gmail and i'm happy to provide details

  • @ggezwpgjnpgaming2186
    @ggezwpgjnpgaming2186 3 года назад +2

    I'm a Pharmacist who is interested in drug to herb interaction studies using in silico methods. Do you have an email address where I could ask for help and more questions? Thank you!
    This video is an effective tool for learning. Thank you so much!

    • @scienceaddicted3431
      @scienceaddicted3431  3 года назад +2

      Hi Ian! welcome to the channel. I'm glad you are interested in _ in silico_ methods. My email address for this channel can be found in the About section. Please write me there, and I'm happy to respond as time allows.

    • @ggezwpgjnpgaming2186
      @ggezwpgjnpgaming2186 3 года назад

      @@scienceaddicted3431 will do. Thank you so much! Keep on making videos!

    • @scienceaddicted3431
      @scienceaddicted3431  3 года назад +2

      @@ggezwpgjnpgaming2186 actually I'm just about to record the voice over, for the next video. Should be ready next week!

    • @ggezwpgjnpgaming2186
      @ggezwpgjnpgaming2186 3 года назад +1

      @@scienceaddicted3431 I'm excited to see that then. Keep up the good work!

  • @mahadxalane3552
    @mahadxalane3552 2 года назад

    good lesson dear teacher can we have your email