Modifying Mosquitoes with CRISPR - AMNH SciCafe

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  • Опубликовано: 29 янв 2017
  • CRISPR gene editing is widely used by biologists as the DNA programming tool of choice to alter the genome of organisms and even populations. By modifying the DNA of mosquitoes, we could prevent them from reproducing-potentially eradicating them completely. But is that something we should actually want to see? Join Rockefeller University professor Leslie Vosshall as she demonstrates what is-and what will be-possible.
    #SciCafe #genes #CRISPR #DNA #geneediting
    This lecture took place at the Museum on January 4, 2016. To learn about upcoming SciCafe events, visit amnh.org/scicafe. To listen to the full lecture, download the podcast: www.amnh.org/explore/news-blog...
    The SciCafe series is proudly sponsored by Judy and Josh Weston.
    SciCafe: Modifying the Mosquito with CRISPR, and related activities are generously supported by the Science Education Partnership Award (SEPA) program of the National Institutes of Health (NIH).
    This video and all media incorporated herein (including text, images, and audio) are the property of the American Museum of Natural History or its licensors, all rights reserved. The Museum has made this video available for your personal, educational use. You may not use this video, or any part of it, for commercial purposes, nor may you reproduce, distribute, publish, prepare derivative works from, or publicly display it without the prior written consent of the Museum.
    © American Museum of Natural History, New York, NY
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Комментарии • 35

  • @kednar
    @kednar 7 лет назад +5

    While we're at editing genes, would it be possible to shift the female mosquitoes' needs from blood to pollen, just as the male mosquitoes?

    • @kimlibera663
      @kimlibera663 5 лет назад

      No. Females feed on blood because this is the protein for their eggs.

  • @ExiledSteel
    @ExiledSteel 7 лет назад +4

    My opinion is, we deleted smallpox without worrying about the outcome. We defeated one subset of species of hookworm, we should do the same with this subset of species of mosquitos.

  • @mark-
    @mark- 7 лет назад +2

    What could possibly go wrong?

    • @Jkstolz
      @Jkstolz 4 года назад

      Covid 19? Cured with anti malaria drugs

  • @r.b.4611
    @r.b.4611 7 лет назад

    Anyway great talk, what an exciting area of interest!

  • @Neueregel
    @Neueregel 7 лет назад +4

    nice talk

  • @atomsk2044
    @atomsk2044 7 лет назад

    How would it get to other insects i wonder.

    • @HebaruSan
      @HebaruSan 7 лет назад +4

      Parasites that feed on both species, maybe? Viruses work by injecting RNA or DNA to hijack the host's resources and reproduction facilities, and that material can make its way into the host's permanent genome (some large percentage of human DNA is from this). I think there's some risk of horizontal gene transfer that way. It's probably a tiny risk, but you have to consider it before going through with something like this.

  • @haroun8332
    @haroun8332 7 лет назад +5

    it's a very sensitive subject because killing mosquitoes isn't the solution and it will shift enormously the balance in nature, we need to study all the consequences before doing anything

    • @sereminar4
      @sereminar4 7 лет назад +4

      You just heard that hundreds of thousands of people die a year because of one species of misquito and you want to wait? We can never study all consequences before doing anything because we would be paralyzed, and never do anything. We must act, because that is the only possible solution.

    • @haroun8332
      @haroun8332 7 лет назад +1

      sereminar4 this subject is a big dilemma, if you ask a biologist or ecologist about the consequences of such act, he will tell you surely that the impact is huge and drastic on the environment, specifically on the food chain of the ecosystem and the interacting between mosquitoes and other animals and plants, the key solution here is finding another set of genes, by which we can stop mosquitoes from biting humans without eradicate them entirely, i think it would be a fair solution for us and for the equilibrium of nature

    • @sereminar4
      @sereminar4 7 лет назад +3

      We aren't talking about eradicating all mosquitos, only like 1 species that mainly (specifically) preys on humans. The bats and birds will just have to eat something else, we've certainly caused mass extinctions and ecological catastrophes for worse reasons. (not that it would really probably be as impactful as the oil spill in the gulf of mexico, for example)

    • @lalalabizola
      @lalalabizola 7 лет назад +1

      Every human intervention in nature is bound to generate disequilibrium. We've been doing it since we originated as species, so you can view the extinction of mosquitoes as something really big and really dangerous or something trivial. The thing is, even if we kill all mosquitoes, people are still going to die for other many (new) reasons.

    • @kimlibera663
      @kimlibera663 5 лет назад

      Incorrect use of scientific method. There are over 1 million species of bugs. Mosquitos cause disease & discomfort. There are many other species to choose from for carnivorous insects. Don't you read a science book?

  • @omrialkabetz5602
    @omrialkabetz5602 6 лет назад

    Is it possible to spread mosquitoes which are immune to malaria and other diseases instead of eradicating the mosquito population?

    • @kimlibera663
      @kimlibera663 5 лет назад

      No. Easier to eradicate via this Darwinian process. The malaria is due to paramecium. Mosquitos still carry other diseases.

  • @bmarley51
    @bmarley51 2 года назад

    Would it be possible to give the females a gene that satisfies their nutritional needs so we are eliminated from their menu and the natural balance is maintained?

  • @jayjohn9680
    @jayjohn9680 2 года назад +1

    Have a video of a scientist looking at a scared little mosquito in the face. Telling it that the game is over… its whole stinking race will be extinct… and somehow the mosquito understands and is looking scared.

  • @michaelbodicker5745
    @michaelbodicker5745 Год назад

    Pandemic of the
    un-vaccinated remember?

  • @r.b.4611
    @r.b.4611 7 лет назад +1

    14:10 "efficacious" Rofl, smart people are changing words to sound smarter. The word you were looking for is "effective".

    • @lifeisgood12341
      @lifeisgood12341 7 лет назад +2

      R.B. both have the same definition

    • @Thedamped
      @Thedamped 7 лет назад +1

      And both words are around 500 years old...

  • @shiloniousmonk
    @shiloniousmonk 6 лет назад +4

    Terrible idea