7. Proto-oncogenes and Oncogenes

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  • Опубликовано: 5 янв 2025

Комментарии • 69

  • @nystagmus
    @nystagmus 5 лет назад +115

    Just made up an mnemonic while you taught a great lecture:
    ONcogene remember ONe hit just needed
    TUmor suppressor remember TWO hits needed for malfunction ( or two more= tumor)

  • @mercytuduo2817
    @mercytuduo2817 Год назад +1

    This entire playlist has been so helpful, I was finding this really difficult earlier. Thank you!

  • @sydneyf77
    @sydneyf77 7 лет назад +11

    i could probably listen to your voice all day

  • @arjavontalebzadeh4579
    @arjavontalebzadeh4579 4 года назад +5

    Thank you again for taking the time to make these amazing concise video series. They have been useful and helpFul for getting a greater understanding of Neoplasias in my foundations block of my M1 year! **Huge applause for your great work**

  • @medexp8593
    @medexp8593 4 года назад +5

    This is such a helpful video, clarifies the concepts really well, and makes it simple to understand. I've referred back to it over last 2 years! thanks

  • @Jason-ig1kg
    @Jason-ig1kg 8 лет назад +9

    Wow this is great. Even though I'm a genetic student, this video explains way better than my professor.

    • @oncologyformedicalstudents6877
      @oncologyformedicalstudents6877  8 лет назад +2

      Thanks, glad you found it helpful!

    • @Jason-ig1kg
      @Jason-ig1kg 8 лет назад +4

      I really love your videos but there is one thing that distracts me and that is the pausing. The pausing is too long between each explanations!

    • @oncologyformedicalstudents6877
      @oncologyformedicalstudents6877  8 лет назад +3

      Jason ngo yeah I've noticed this too- I've just changed the way I'm recording the audio so it should limit these pauses- thanks for the feedback!

  • @alhawaiigirl2651
    @alhawaiigirl2651 8 лет назад +111

    edit out those sniffles. lol great vid though

    • @oncologyformedicalstudents6877
      @oncologyformedicalstudents6877  8 лет назад +35

      Ha! Not sure i'm quite tech savvy enough to do that...i'll try my best to be less sniffly in future recordings! Glad you found the video useful

    • @Yuksel101
      @Yuksel101 7 лет назад

      Allie Socher I

    • @xDomglmao
      @xDomglmao 4 года назад +7

      @@oncologyformedicalstudents6877 let them in! creates a nice chill atmosphere! :)

  • @mongtrantran3960
    @mongtrantran3960 6 лет назад +5

    Familial cancer syndromes, the majority of which are caused by inheritance of a mutant timor suppressor gene, usually afflict distinct tissues even though all cells in the body contain the inherited mutation. Can you please explain what reasons might underlie this tissue-specific tumor development?

  • @dzekapeka
    @dzekapeka 7 лет назад +3

    Not a med student but enjoy these videos nevertheless. Thanks for helping me learn!

  • @Will-ql5db
    @Will-ql5db 2 года назад +1

    MARVELOUS explanation, sir. Thank you.

  • @rizkyaprilia2916
    @rizkyaprilia2916 6 лет назад +1

    all of your videos are great and helpful. thank you so much!

  • @KJKP
    @KJKP 8 лет назад +1

    It seems GTPase and GAP function similar to a G protein-coupled receptor.

  • @soulgoogleuser4980
    @soulgoogleuser4980 6 лет назад +31

    please re-record that without the sniffling. it is such a great lecture but the sniffles are really throwing me off. sorry to say that but please re record

    • @booesha2
      @booesha2 6 лет назад +19

      Ungrateful...get over it or find a different video.

    • @sadikcannakib
      @sadikcannakib 2 года назад

      Naturality

  • @AurineliaSumomba
    @AurineliaSumomba 2 месяца назад

    Thank u for the explanation!! Very helpful

  • @shanasaeed6351
    @shanasaeed6351 6 лет назад

    This was much needed.
    Thank you!

  • @dr.paddlesmack2054
    @dr.paddlesmack2054 4 года назад +1

    awesome video, the sniffing wasn't a big deal.. great content

  • @halaalabboud480
    @halaalabboud480 7 лет назад +1

    That was more than great.
    Thanks

  • @heba6746
    @heba6746 Год назад

    Very informative thank you

  • @yasmine9046
    @yasmine9046 3 года назад

    Excellent explanation thank you so much!

  • @Jean-zr3rn
    @Jean-zr3rn 8 лет назад

    Anyone know what the participation of the proto-oncogene and oncogene in the formation of benign neoplasia?

    • @oncologyformedicalstudents6877
      @oncologyformedicalstudents6877  8 лет назад +1

      I imagine the same oncogenes are involved, but the cells in benign neoplasms have only acquired mutations that allow them to proliferate, rather than the other behaviours seen in malignant tumours (e.g. invasion, metastasis)

  • @lamaz2809
    @lamaz2809 7 лет назад

    how do proto oncogenes related to oncogenes

  • @jenniferboylan7127
    @jenniferboylan7127 6 лет назад +46

    honestly can not get passed the sniffling...

  • @victorr5289
    @victorr5289 7 лет назад +4

    It looks very good but I have a problem understanding your accent. English is not my first language. Could you please put subtitles?

    • @Abominatrix650
      @Abominatrix650 7 лет назад +1

      I agree! Although I'm an English speaker, I have trouble focusing and subtitles would really help.

  • @saucysauce204
    @saucysauce204 6 лет назад +8

    omg the sniffles :) dying

  • @farahhisham884
    @farahhisham884 8 лет назад +4

    wow ! that couldn't be explained easier ! only these sniffs tho are a bit distracting XD

  • @JMoneyMAFIA321
    @JMoneyMAFIA321 6 лет назад +1

    that sniff @1.48

  • @andreswalker6638
    @andreswalker6638 Месяц назад

    The pictures are awesome but the video wasnt the easiest to follow. Plus like they said his illness interrupts the video

  • @arutussupova6708
    @arutussupova6708 3 месяца назад

    get well soon

  • @ughsirius
    @ughsirius 2 года назад

    Thank you!!

  • @daynadixon_
    @daynadixon_ 3 года назад

    Thank you!

  • @Rugie10
    @Rugie10 7 лет назад +6

    using the car to explain is helpful

  • @AbdaluzizA
    @AbdaluzizA 8 лет назад +1

    ahhh I love Maaaaan thank you sooo much

  • @Val_the_therian62442
    @Val_the_therian62442 5 лет назад

    Great Video but as other people have menioned would be ALOT better if recorded it when you were not so sick. It sounds horrible and keep thinking the video players froze up or something is wrong .

  • @aman8443
    @aman8443 7 лет назад +1

    good, but you could be more clear about the differences between tumor-supressor-genes and protooncogenes :)
    thank u

    • @oncologyformedicalstudents6877
      @oncologyformedicalstudents6877  7 лет назад

      Aman Rezai thanks for the comment! the last slide here describes the difference between proto-oncogenes and tumour suppressor genes - do you mean that this slide isn't clear or needs more detail?

    • @aman8443
      @aman8443 7 лет назад

      oops I see. I get my word back. the answer is much lear in last slide. Thank you.

    • @oncologyformedicalstudents6877
      @oncologyformedicalstudents6877  7 лет назад +2

      no worries! thanks for watching!

  • @cablackcablack
    @cablackcablack 5 лет назад +2

    So cute sniffles >.

    • @duai7090
      @duai7090 3 года назад

      👁👄👁

  • @nazzib3657
    @nazzib3657 5 лет назад +1

    Awesome video but pls blow ur nose next to me U start a video!!! 😩

  • @yazeedbinsamman831
    @yazeedbinsamman831 7 лет назад

    Subscribe for you

  • @ethannorton1827
    @ethannorton1827 8 месяцев назад

    helpful but quit sniffing into the mic and edit better

  • @francescamazza7303
    @francescamazza7303 6 лет назад

    Speak a little bit faster eh! Thanks a lot....

    • @Entroxity
      @Entroxity Год назад

      You know you can slow the video down... Well, I don't expect someone as unintelligent as you to know how to do that.

    • @Entroxity
      @Entroxity Год назад

      Of course, an italian, who else would it be. The most entitled, arrogant people I've come across in med school.