Thanks for the explanation! At University my Professor explained just the mechanism of protein localization, and I studied without understanding a lot. Is so interesting to know the different approches used to understand this cellular mechanism. Thanks again!!!
(On Tuesday of April 18, 2023). ON the Matter of GMOs and PhD Ramanujan Hegde (MRC) and Quality Control of Protein Localization: 1) Endoplasmic Reticulum Stress-Associated Proteins and ER Associated Degradation (ERAD) certainly must be flawed in Pathology of Deposition (Tau Proteins, Amyloid Plaques) and Neurodegeneration is Perhaps the Most Preventable Disease Process of Geriatrics, for Alzheimer's Onset is late Age and its Morbidity is the only Limiting Factor where Death mainly ensues by this Inefficacious and Overburden Metabolism of Pathological Protein Biosynthesis. Certainly, the understanding of this Process Homeostatically will yield results of Vast Pharmacotherapeutics (I almost already sense Enzyme Proteomics of Recombinant DNA Technology alleviating this Pathology slightly). Prions (PrP) Disease and the awful Process of Proteins being Aetiologic Agents of Infectivity has to be an Idiopathic Process while Science helplessly concerns it efforts in Spreads or in trivial Investigations of Pathway Modulation (Carcinogenesis and Autophagy) or even Metabolism Alteration (GLP-1 Memetics and the Stupefaction of Mediating Diabetes) when essentially Pathology Recognition and Re-Envisionment is Primary and Wanting. I mean what is to be understood in a Hormone Pathological Milieu of Self-Destruction, ie Contraception via Estrogen Intake or the Gluttonous Monosaccharidosis of Diabetes Mellitus Insulin Resistence or worse yet treating a Psychosis as if was simply a Metabopathy. 2) I do feel this Investigation, as lethargic and Ill-funded it might be, is Meritorious (Protein Localization) in just about in every way important (Geriatrics, Primary Care Medicine of Prophylaxis) and even the Crux of My Inquisition, Metabolic Inherited Diathesis--Progeria And the Inevitability to even Develop let alone Prosper is serious Pathology. I make all efforts and Means to Remediate the Nature's Curse while abstain absolutely in the Disease Profiteering or Mediation (Symptomatic Costly Remediation is far from Humanism's Value or Ideal therein). While therapies of dubious and reckless Expenditure HAART, Statin Therapy, Hyperglycemic Controls are active areas of Science, they too are as flawed in Means and Ends as Making Antibiotics for Hyper-antibiolgicals, that is over reliance on Chemotherapy of Antibiotics. This is not only Breeding Antibiotic Resistance but also Biohazardous Live Matter--Walking, Talking Biological Warefare is not either a Right or a Peaceful Sound Approach to Infectious Disease. PhD Ramanujan Hedge, es muss haben gewessen besser aber heute wir werden sehen Apokalpse der Endmannschafts. Heil!
thank you for clearly and concisely explaining this exciting subject. you are a master teacher.
Thanks for the explanation! At University my Professor explained just the mechanism of protein localization, and I studied without understanding a lot. Is so interesting to know the different approches used to understand this cellular mechanism.
Thanks again!!!
(On Tuesday of April 18, 2023). ON the Matter of GMOs and PhD Ramanujan Hegde (MRC) and Quality Control of Protein Localization: 1) Endoplasmic Reticulum Stress-Associated Proteins and ER Associated Degradation (ERAD) certainly must be flawed in Pathology of Deposition (Tau Proteins, Amyloid Plaques) and Neurodegeneration is Perhaps the Most Preventable Disease Process of Geriatrics, for Alzheimer's Onset is late Age and its Morbidity is the only Limiting Factor where Death mainly ensues by this Inefficacious and Overburden Metabolism of Pathological Protein Biosynthesis. Certainly, the understanding of this Process Homeostatically will yield results of Vast Pharmacotherapeutics (I almost already sense Enzyme Proteomics of Recombinant DNA Technology alleviating this Pathology slightly). Prions (PrP) Disease and the awful Process of Proteins being Aetiologic Agents of Infectivity has to be an Idiopathic Process while Science helplessly concerns it efforts in Spreads or in trivial Investigations of Pathway Modulation (Carcinogenesis and Autophagy) or even Metabolism Alteration (GLP-1 Memetics and the Stupefaction of Mediating Diabetes) when essentially Pathology Recognition and Re-Envisionment is Primary and Wanting. I mean what is to be understood in a Hormone Pathological Milieu of Self-Destruction, ie Contraception via Estrogen Intake or the Gluttonous Monosaccharidosis of Diabetes Mellitus Insulin Resistence or worse yet treating a Psychosis as if was simply a Metabopathy. 2) I do feel this Investigation, as lethargic and Ill-funded it might be, is Meritorious (Protein Localization) in just about in every way important (Geriatrics, Primary Care Medicine of Prophylaxis) and even the Crux of My Inquisition, Metabolic Inherited Diathesis--Progeria And the Inevitability to even Develop let alone Prosper is serious Pathology. I make all efforts and Means to Remediate the Nature's Curse while abstain absolutely in the Disease Profiteering or Mediation (Symptomatic Costly Remediation is far from Humanism's Value or Ideal therein). While therapies of dubious and reckless Expenditure HAART, Statin Therapy, Hyperglycemic Controls are active areas of Science, they too are as flawed in Means and Ends as Making Antibiotics for Hyper-antibiolgicals, that is over reliance on Chemotherapy of Antibiotics. This is not only Breeding Antibiotic Resistance but also Biohazardous Live Matter--Walking, Talking Biological Warefare is not either a Right or a Peaceful Sound Approach to Infectious Disease. PhD Ramanujan Hedge, es muss haben gewessen besser aber heute wir werden sehen Apokalpse der Endmannschafts. Heil!
Sir, i want to join your lab... I Iove molecular biology
I felt sorry for the ataxic mouse