Selectively Silencing Nociceptor Sensory Neurons│Prof. Clifford J. Woolf

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  • Опубликовано: 17 ноя 2021
  • Summary:
    Local anesthetics decrease the excitability of all neurons by blocking voltage-gated sodium channels non-selectively. We have developed a technology to silence only those sensory neurons - the nociceptors - that trigger pain, itch, and cough. I will tell you why and how we devised the strategy, the way we showed that it works, and will also discuss its implications for treating multiple human disorders.
    Speaker Bio:
    Clifford J. Woolf, MB, BCh, PhD, was born and educated in South Africa, became a Neurobiology Professor at University College London, then the Richard J. Kitz Professor of Anesthesiology Research, Massachusetts General Hospital/Harvard Medical School. Presently, he is the F. M. Kirby Neurobiology Center Director, Boston Children’s Hospital, and a Neurology/Neurobiology Professor at Harvard Medical School. Dr. Woolf’s many honors and prizes include membership in the American Academy of Arts and Sciences, a Doctoris Honoris Causa (University of Lausanne, Switzerland), a Gill Distinguished Scientist Award, and the Reeve-Irvine Medal. He works on adaptive and maladaptive plasticity of the nervous system.
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Комментарии • 2

  • @selahchunem8447
    @selahchunem8447 Год назад

    I run into this video by accident tonight after running into some notes on my desk. A technique for post traumatic shock syndrome was abbreviated EMDR therapy. For some reason it triggered a remembrance of some another technique that I was exposed to years ago as a chiropractor basically known as nocirecptor sensory blocking technique. It was being taught by chiropractors that supposedly had advanced diplomatic training in neurology. They claimed this technique was proven and showed clinical efficacy for pain blocking. Long story short over the years because of my spiritual beliefs as well as clinical experience I ran into some of the stuff again and was questioning it because when I tried to use it in clinical life I had up-and-down results. It also was linked to a technique called EFT or EBT Known for emotional blocking technique. Basically both these formats and applications involved tapping multiple times on strategic points in the body that were supposed to connect to traditional Chinese or accupressure points. Personally I've always been questionable about acupuncture acupuncture points even though I dabbled here and there. I heard people using those techniques with results. Most recently after falling back into some muscle testing diagnostic techniques that we're not well documented clinically or scientifically, I discovered they were actually pagan new age and possibly full of divination. Though I ran from them and stopped using them only on me during by retired life .The tapping techniques seem to be connected to that new age acupuncture realm of healing. So I never used that stuff again. But I was wondering if you ever ran into any of your clinicians or patients that we're exposed to any of these techniques. I just alluded to proponents of these techniques especially the nocisreceptive technique claim that it dramatically decreased both acute and chronic pain quickly and effectively, but it is not the replacement for viable and necessary medical treatment. That was their disclaimer or caviat. So if nothing else your discussion and title of your video was nostalgic for me.

  • @johnathanabrams8434
    @johnathanabrams8434 Год назад

    It's unbelievable how worthless medications are for chronic issues