Whole Genome Sequencing: What Can You Expect?

This video provides an overview of a genetic test called whole genome sequencing (WGS). It will cover an introduction to genetics, some applications of WGS, the types of findings you can expect from this test, and the advantages and potential risks of WGS. The video was developed to help you understand how this comprehensive genetic test works and what its results can tell you. Whether you want to learn more about this test or are considering getting your genome sequenced, we hope this video helps you feel more informed and confident in your decision. This video was developed by students of the Masters of Medical Genomics program at the University of Toronto - Gabriela Tanumihardja, Neta Pipko, and Sornnujah Kathirgamanathan.
00:00 - Introduction: The Genome
02:38 - Applications of Whole Genome Sequencing
06:18 - Primary Findings
09:34 - Secondary Findings
12:53 - Incidental Findings
17:02 - Making Your Decision
License: Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
MUSIC:
Progress by gilv elemgilt.envato.com/progress-...
License: NDK5EYH6JC
REFERENCES:
docs.google.com/document/d/1w...

[@Thabiiwabii]

I’m a 3rd year Molecular Medicine student and this video really helped me understand WGS 😭🙏🏽

[@Drsilmi]

Can genetic sequencing detect chromosomal abnormalities/aberrations?

[@kevinnavarrohernandez8649]

No, for chromosomal abnormalities the tests used are karyotyping and/or fluorescent in-situ hybridization (FISH)

[@sornnujahkathir3117]

Depending on the type of chromosomal aberration, you may be able to detect them through WGS. Long read sequencing may perform better when detecting certain abnormalities, such as balanced translocations.

[@Drsilmi]

@@sornnujahkathir3117 okay let’s say a trisomy or a monosomy ?