Mitochondrial DNA And D Loop Replication

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  • Опубликовано: 11 дек 2024

Комментарии • 169

  • @EasyPeasyLearning
    @EasyPeasyLearning  2 года назад +9

    Correction: 8:09 The Outer Strand (Black) Is The Heavy Strand And The Inner Strand (Red) Is The Light Strand.
    Correction: 14:09 The Hairpin Like Structure Form On the The Light Strand Is Located On The Inner Side Of The Ring.
    If your subtitles are on then a correction will also display during the given time stamps.

    • @anshabarakzai9567
      @anshabarakzai9567 2 года назад +1

      I don't know why, but you remind me of my biochemistry instructor from the University of Manitoba. you sound exactly like herrrr.

    • @pelajarpusing6403
      @pelajarpusing6403 Год назад +1

      Hi, i'm a bit confused here. In 8:09 you mention that there is a correction between the heavy strand and the light strand part. Is it include the explanation? If the light strand mention as the red one, is the explanation also belong to the red one? Or it still as it, and all i need is just switch the labeled? I mean is it : "The L strand contain a lot of Guanines" and forth or is it still "The H strand contain a lot of Guanines" like you said on the video?. I hope you understand. Also i'm sorry for my bad English since it isn't my first language. Thank you so much. I hope you a joyful day

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      Hi Pelajar, your English is perfect 👌 dear, the explanation for both strands is correct only the location part was wrong. So guanines are present in H strand but the strand should be present outside not inside.

    • @pelajarpusing6403
      @pelajarpusing6403 Год назад +1

      @@EasyPeasyLearning Aah, i see!! Thanks a lot. I will continue to watch, take a note, and sponge it into my brain. Thank you so much!

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      You are welcome 😊

  • @mohammedal-hammadi5085
    @mohammedal-hammadi5085 3 года назад +8

    This channel should be followed by millions, because we won't find a better one!👍🏻

    • @EasyPeasyLearning
      @EasyPeasyLearning  3 года назад +1

      Thank you 😊

    • @kaydee3407
      @kaydee3407 2 года назад

      @@EasyPeasyLearning
      Do u have a separate blog or playlist on mitochondria science ..
      I am researching the effect of nucleoside analogies on mitochondrial polymerase...and mitochondrial dna .
      can u point me in the right direction ...any experts in this field or papers ...

  • @RohitPant04
    @RohitPant04 3 года назад +15

    Note: Heavy and light strand are called so due to their masses. Adenine and Guanine composition is heavy while Cytosine and Thymine have a lighter mass, hence, heavy strands would have higher number of A, G while light strands would have higher number of C, T.

  • @sudhakarreddy1453
    @sudhakarreddy1453 3 года назад +8

    I never thought mitochondrial DNA has this much of mechanisms with it
    Great lecture

  • @jyotinayak4234
    @jyotinayak4234 Год назад +2

    After searching in many videos finally got the right one☺tq so much ma'am🤗

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      Hi Jyoti, make sure you have read the correction notes in the video. If not make sure to read the comments. There was a little mistake in the replication process which youtube wouldn't allow me to correct after publishing. Thank you 😊

  • @sunduszahidful
    @sunduszahidful 3 года назад +2

    Thankyou very much. It was the best video I have watched about mitochondrial dna. You saved alot of time. 💞

  • @mol_biologist30
    @mol_biologist30 2 года назад +2

    Your video lectures are so beautifully explained with diagrams and short notes ! thank you so much ma'am !

  • @harshaahra6545
    @harshaahra6545 3 года назад +1

    Great job guys, as soon as i finished video, i jumped onto subscription button .... Really appreciated work...

  • @daianadepetris2742
    @daianadepetris2742 Год назад +1

    Hi! This video is so good!! thanks from Argentina!

  • @liadiafarida6428
    @liadiafarida6428 3 года назад +1

    this one is really the-most-easy-peasy explanation, thank you :""""""

  • @bighmay12
    @bighmay12 2 года назад +3

    Thank you for this. It was extremely helpful and pleasant to listen to.

  • @RohitPant04
    @RohitPant04 3 года назад +3

    Quite a properly summarized presentation. Thanks!

    • @EasyPeasyLearning
      @EasyPeasyLearning  3 года назад

      You are welcome. Your note is quite helpful for the people. Thanks 👋 😊

  • @malikishfaq2978
    @malikishfaq2978 Год назад +1

    Awesome Explanation ...Nicely Explained ....

  • @mfaizalabubakar3492
    @mfaizalabubakar3492 4 года назад +2

    Thank you. Really helps me to understand mitochondrial genome as i'm currently doing mitochondrial genome sequence assembly

  • @user-pg2tg2qr5b
    @user-pg2tg2qr5b 2 года назад +1

    Simply Brilliant! God Bless You!

  • @adammajaliwa3125
    @adammajaliwa3125 2 года назад +1

    Your lecture is so amazing, really educative. 🤔 keep climbing madam👏👏👏

  • @gecorp
    @gecorp 2 года назад +1

    amazing super clean explanation!!! well done

  • @ishi3764
    @ishi3764 2 года назад +1

    A lots of help from this lec. thnku so much mam

  • @brentweissert6524
    @brentweissert6524 2 года назад +1

    thank you for a most informative presentation. the illustration in my biology book left me confused, but thanks to your video i no longer am confused--at least not about this!

  • @Alex-5d-space
    @Alex-5d-space 4 месяца назад +1

    This information about DNA is very important connection point.
    So women and man have One type of mitochondrial-DNA and it's evolves diferently from nuclear-DNA... We all are brothers and sisters as we have One same history of m-DNA for all of us = 1 .... we all have this "One"
    Mitochondrial DNA in the form of a closed cycle, a closed cycle in the form of a “Mjobius strip” = this an important point for discussion and development.
    Awesome chanel = Easy Peasy! B)

    • @EasyPeasyLearning
      @EasyPeasyLearning  4 месяца назад +1

      Hi, your approach towards the topic is really interesting. Thank you for your comment 😊

  • @merlyasammers255
    @merlyasammers255 4 года назад +2

    omg thank you so so much!!! Amazing explanation very clear and in depth

    • @EasyPeasyLearning
      @EasyPeasyLearning  4 года назад

      You are welcome. You can also tell me the topics which is hard for you to understand. Please subscribe my channel 🙏

    • @elifc5975
      @elifc5975 4 года назад +1

      @@EasyPeasyLearning hi! Firstly thanks for the explanation, it helped me a lot :) and i am struggling with "Cellular Compartmentation and Protein Sorting" can you make a video about it? 😊✨

    • @EasyPeasyLearning
      @EasyPeasyLearning  4 года назад

      @@elifc5975 sure I will.

    • @elifc5975
      @elifc5975 4 года назад

      @@EasyPeasyLearning OMG thank you sm :)

  • @wanyikchai6397
    @wanyikchai6397 3 года назад +2

    Thank you so much! Very detailed explaination!

  • @Aanyaa_31
    @Aanyaa_31 Год назад +1

    Amazing explanation!

  • @zazajoey138
    @zazajoey138 3 года назад +1

    Thank you! This video is of high quality and detailed.

  • @mamtapatel4218
    @mamtapatel4218 4 года назад +1

    Very nicely explained....thank you ma'am ❤️❤️

  • @MRauf3021
    @MRauf3021 2 года назад +1

    Well illustrate with diagrammatically ✨❣️🇵🇰

  • @alaazein7147
    @alaazein7147 3 года назад +2

    You are very good. Very very
    Thank you very much ❤️

  • @nicoleevans5943
    @nicoleevans5943 4 года назад +1

    thank you so much, all the videos I saw before didn't explain how the 4 strands get separated and I was really confused.

  • @lulou3970
    @lulou3970 3 года назад +3

    I tried to understand this during hours, before everything became much more clear with this video. Thanks so much for the illustrations, you gained one sub. I'm not sur but the light strand is the inner one no ? Either way, thank you so much for explaining the mecanism, that's the most important part.

    • @EasyPeasyLearning
      @EasyPeasyLearning  3 года назад

      Yes the light strand is the inner strand. We did put the note on the video, not sure why is it not showing up for everyone. Thank you for your subscription.

  • @priyankadhawan3398
    @priyankadhawan3398 2 года назад +1

    Awesome explanation

  • @GlidyBun
    @GlidyBun 3 года назад +2

    Excellent video!

  • @afreenbegum7841
    @afreenbegum7841 Год назад +1

    Nice explanation 😊

  • @srikantpanda7993
    @srikantpanda7993 Год назад +1

    Great content 🙏

  • @monicavaldez7746
    @monicavaldez7746 3 года назад +1

    Super easy to understand, thank you!

  • @sangitalala9133
    @sangitalala9133 4 года назад +2

    Nicely explained. thanks.

  • @ashiali4047
    @ashiali4047 4 года назад +2

    Really helpful 😍

  • @naumanarif2772
    @naumanarif2772 4 года назад +3

    Thank you for the valuable information.
    Please if you share the article papers related to difference between mitochondrial DNA and nuclear DNA.
    It will be a great help from you.

    • @EasyPeasyLearning
      @EasyPeasyLearning  4 года назад

      www.ncbi.nlm.nih.gov/pmc/articles/PMC3504440/?fbclid=IwAR20OvnPo8-bRdHRBwyHk7-cK7P6Hy4xyWe4RjpAe3nw5p-N6L_rRPRGy1Q

    • @EasyPeasyLearning
      @EasyPeasyLearning  4 года назад

      www.sciencedirect.com/topics/neuroscience/mitochondrial-dna-replication?fbclid=IwAR3jNmAOnCknwHl33QjbDSJ4H-nqsFmqct1AG1zn71LzyjMQVZBTH-vZqoM

    • @EasyPeasyLearning
      @EasyPeasyLearning  4 года назад

      www.ncbi.nlm.nih.gov/pmc/articles/PMC6056714/?fbclid=IwAR2wWhu63AitVtaszo2AgOAulE2Ff4kY7JrxYj21kZ_WBVLXpFRvmXcA2nI

  • @iBrandzz
    @iBrandzz 3 года назад +1

    clear all concept...thank you

  • @samirbrahimi5782
    @samirbrahimi5782 3 года назад +1

    well explained tnx alot

  • @khushbubedi1426
    @khushbubedi1426 2 года назад +1

    Outstanding

  • @mengqiaoyang1092
    @mengqiaoyang1092 3 года назад +3

    Should the outer strand be the heavy strand? Because all the mtDNA maps show the OH is located on the outer strand.

    • @EasyPeasyLearning
      @EasyPeasyLearning  3 года назад

      Hi Mengqiao, thank you for mentioning the error. We will put the note on the video to fix this problem.

  • @دعاءعبدالرسول
    @دعاءعبدالرسول Год назад +1

    Thank you soo much help🙏

  • @nesrinech3967
    @nesrinech3967 3 года назад +1

    thank you so much, this is exactly what i needed

  • @prashantkumarparmanu
    @prashantkumarparmanu 2 года назад +1

    great video

  • @ishratbhat410
    @ishratbhat410 6 месяцев назад +1

    Very nice

  • @pei-yintsai783
    @pei-yintsai783 4 года назад +1

    thank you! it's very helpful

  • @medicalstudent1575
    @medicalstudent1575 5 месяцев назад

    In mitochondrial DNA is there histone proteins?

  • @anjalikalwar2775
    @anjalikalwar2775 2 года назад +1

    I think I found a mistake in the video. The Heavy strand is the outer strand and the light strand is the inner strand unlike indicated in the video.

    • @EasyPeasyLearning
      @EasyPeasyLearning  2 года назад

      You are right Anjali I did made a note for that on the video. Unfortunately it doesn't show up all the time and youtube doesn't have the feature that I can ammend it in the same video.

  • @mohamedamineamellal-vl2fc
    @mohamedamineamellal-vl2fc Год назад +1

    Thank you sooo muchhh

  • @elizabet3241
    @elizabet3241 4 года назад +1

    very useful .may also explain about oxidative stress effects on mtDNA?

  • @ayeshawaqar9561
    @ayeshawaqar9561 Год назад

    Can u pls upload lecture on chloroplast DNA replication

  • @Y.Sowmyakrishna_official
    @Y.Sowmyakrishna_official Год назад +1

    Mam wonderful lecture about mitochondrial DNA replication.
    But I have a small doubt in it .
    Some lectures and in some book's it is saying that H strand is inside, L strand is outside.........
    Please tell me mam which is correct

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад +1

      Hi Sowmya, yes dear it was confusing thats why I made a mistake in a video and made a correction note on it. H strand is outside and L strand is inside. Thats confirmed in more 📚 then the other.

    • @Y.Sowmyakrishna_official
      @Y.Sowmyakrishna_official Год назад +1

      @@EasyPeasyLearning thank you mam

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      You are welcome 😊

  • @antoniocacciapaglia9391
    @antoniocacciapaglia9391 Год назад +1

    thanks, but i didn't understand well a thing: H strand and L strand are double helix both?

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад +1

      Hi there, no the dna double helix, when it unwind itself, 1 will be called as H strand and other will be called as L strand.

    • @antoniocacciapaglia9391
      @antoniocacciapaglia9391 Год назад +1

      @@EasyPeasyLearning thx again!

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      You are welcome 😊

    • @ZxZx-l5o
      @ZxZx-l5o Год назад

      The inner strand is known as L strand /light strand as it has more pyrimidine bases like (T and C) ...wheras the outer strand is called H /heavy strand becoz it has more purine bases ( A and G) ....so they ....they r the 2 strands of dna bouble helix

  • @affan7130
    @affan7130 3 года назад

    This video is very useful for me.. can you please provide PDF notes?

  • @rummufirdous9705
    @rummufirdous9705 Год назад +1

    Heyyy hiii
    I liked your lecture can u please guide me
    If I can write this in my plant gentics paper as I have a paper tomorrow and do you have chloroplast genome orgasation and plant genome organisation ?

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      Hi Rummu, yes you can write it in the paper, however there are some correction notices made on the video, make sure you read them.

    • @rummufirdous9705
      @rummufirdous9705 Год назад +1

      @@EasyPeasyLearning Thankyou so much mam
      Will make sure to look into it and hope your channel becomes big as many students need this type of lecture ❤️

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      Thank you 😊 💓

  • @Adnankhan-un7bw
    @Adnankhan-un7bw 3 года назад +2

    Thankyou Soo much, but i have one question that is, if the outer black line is H-strand and inner one is L-strand soo it means replication start first at L- strand?plzz respond quickly.

    • @EasyPeasyLearning
      @EasyPeasyLearning  3 года назад +1

      Hi Adnan, No the replication of H strand starts first like it was explained in the video. L STRAND will make loop but on the inner side not on the outer side

    • @Adnankhan-un7bw
      @Adnankhan-un7bw 3 года назад +1

      @@EasyPeasyLearning soo the inside nascent loop which is shown in light blue color, is it nascent H-strand? And if it is nascent H-strand soo why it is shown inside and surrounded by L- strand? Please remove my confusion

    • @EasyPeasyLearning
      @EasyPeasyLearning  3 года назад +2

      Hi Adnan All the information provided in the video is correct, the only mistake was light strand should be presented inside and H strand should be presented outside. In the last part where you can see 4 circles. If that mistake was not there, the yellow circle should be the old H strand, black circle should be the new Strand replicated H strand, blue circle should be the new strand replicated L strand and red circle should be the old L strand. RUclips doesn't allow to make changes like that in the video but will attach the correct picture in the comments soon to remove the confusion.

    • @Adnankhan-un7bw
      @Adnankhan-un7bw 3 года назад +2

      @@EasyPeasyLearning Ok now it is cleared to me. Thankyou soo much❤️.Appreciated!

    • @EasyPeasyLearning
      @EasyPeasyLearning  3 года назад +2

      Glad to help you ☺. Take care

  • @Muzee123
    @Muzee123 Год назад +1

    Outer strand is black called Heavy chain and red coloured is light chain

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      Yup thats correct, we have already made a correction note on the video.

  • @twwqaz
    @twwqaz 4 года назад +1

    When doing species identification, people suggest to use mtDNA sequence rather than nuclear DNA.
    Is it because the genes code for protein in mRNA of mtDNA is relatively smaller than that of nuclear DNA?

    • @EasyPeasyLearning
      @EasyPeasyLearning  4 года назад +1

      Yes that is 1 of the main reason to use mitochondrial DNA as it code for limited number of proteins and is easy to use for identification.

    • @twwqaz
      @twwqaz 4 года назад +1

      @@EasyPeasyLearning Using mtDNA over nuclear DNA for the phylogy of species, is it because the information in mtDNA will be consistant in every generation, while DNA info change alot when offspring inherit from parents in every generation

    • @EasyPeasyLearning
      @EasyPeasyLearning  4 года назад +1

      S tobe read this article
      pubs.er.usgs.gov/publication/1013321

    • @twwqaz
      @twwqaz 4 года назад +1

      @@EasyPeasyLearning Thank you so much!

    • @EasyPeasyLearning
      @EasyPeasyLearning  4 года назад

      @@twwqaz you are welcome 😊

  • @elizabet3241
    @elizabet3241 4 года назад +1

    thanks a lot

  • @Y.Sowmyakrishna_official
    @Y.Sowmyakrishna_official Год назад

    But Mam how the hair pin like structure forms on the light strand.
    Please tell me .

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад +1

      Hi Sowmya, the hairpin loop on light strand will be form on the inner strand towards the outer circle

  • @Farhan-co9he
    @Farhan-co9he Год назад +1

    great

  • @louizafella8838
    @louizafella8838 2 года назад +1

    Thank youu

  • @abhaypanda16
    @abhaypanda16 7 месяцев назад +1

    Supper

  • @AbhiramN_1289
    @AbhiramN_1289 Год назад

    Twinkle Twinkle Little Star! I have to meet the scientist who named that that!

  • @AjithKumar-iu1ri
    @AjithKumar-iu1ri 3 года назад +1

    👌👌👌

  • @OrdinaryXtreme
    @OrdinaryXtreme 3 года назад +1

    Hello, guys, thanks for the video! Can you please share your sources? I'd like to read further about it :D

    • @EasyPeasyLearning
      @EasyPeasyLearning  3 года назад

      www.ncbi.nlm.nih.gov/pmc/articles/PMC6056714/?fbclid=IwAR2wWhu63AitVtaszo2AgOAulE2Ff4kY7JrxYj21kZ_WBVLXpFRvmXcA2nI
      www.sciencedirect.com/topics/neuroscience/mitochondrial-dna-replication?fbclid=IwAR3jNmAOnCknwHl33QjbDSJ4H-nqsFmqct1AG1zn71LzyjMQVZBTH-vZqoM
      www.ncbi.nlm.nih.gov/pmc/articles/PMC3504440/?fbclid=IwAR20OvnPo8-bRdHRBwyHk7-cK7P6Hy4xyWe4RjpAe3nw5p-N6L_rRPRGy1Q

    • @OrdinaryXtreme
      @OrdinaryXtreme 3 года назад +1

      @@EasyPeasyLearning thank you so much!!

  • @hosoiarchives4858
    @hosoiarchives4858 Год назад

    How does the body use mt DNA

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      Hi there, Mitochondrial DNA is necessary for the proper function of mitochondria and the major function of mitochondria is to produce energy (ATP) by the process of cellular respiration.

  • @okpolihenry983
    @okpolihenry983 Год назад +1

    how can i subscribed more than once ?

  • @yasminemouna5252
    @yasminemouna5252 2 года назад +1

    💛

  • @AbhiramN_1289
    @AbhiramN_1289 Год назад

    Okay, so the relative position of the heavy strand and the light strand varies.

    • @EasyPeasyLearning
      @EasyPeasyLearning  Год назад

      Hi there, apology for late reply, yes if you can see the correction notes present on the video the position of H strand and L strand varies

  • @deepikamahto8039
    @deepikamahto8039 8 месяцев назад +1

    ⭐️⭐️⭐️⭐️

  • @bio366geethasankar7
    @bio366geethasankar7 7 месяцев назад +1

    🙏🙏🏻💖

  • @SteveMattHahn
    @SteveMattHahn 2 года назад

    In regards to the mention of evolutionary studies at 0:28, nothing in God's creation evolves, but all things decay.