I have a question about endosomes. Can you find there a membrane protein that’s on its way to the membrane? I mean after it’s synthesized and it’s ready to head to the membrane . And what is the journey this protein has from the cell to the membrane (what organelles does this protein have to go through in order to get eventually to the membrane)?
Could you explain for me the arrows from the late endosome ưhich then fuse with autophagosome/phagosome to make lysosome please ? By the ưay, your video is very comprehensive, thanks
If the vesicle is large (>250 nm in diameter), the method is called phagocytosis (cell eating), and the vesicle is a phagosome. If the vesicle is small (
+Sia It does ish. So the TGN (Golgi) makes the enzymes, which fuse to the late endosome. The late endosome is not yet acidic enough to activate the hydrolases, but when it does become acidic enough, the late endosome morphs to a lysosome, and all of the M6P/other components of the original TGN clatherin vesicle are degraded.
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One of the best explanation i ever heard on cell biology. Thank you so much.
Thank you so much for appreciating my efforts
Thank you Suman, this cleared up some confusion I had regarding the endosome's relationship to the autophagosome.
Thank you!! Finally some clarity on these terms!
Excellent summary and explanation. Thank you sir 🙏
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short and straight to the point ! thank you !
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THANK YOU SIR I UNDERSTOOD EVERYTHING CLEARLY
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You should know that there is a different particular term to describe the case of a cell engulfing liquid. It's Pinocytosis.
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It is a clarifying lecture, thanks a lot
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Amazing explanation 💯💯
Thank you
@@shomusbiologyofficial Welcome... please keep making amazing videos like these❤
Thanks vai..
& congratulations for 1M subscribers..
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Perfectly described each n everything ❤
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from last 2 days i was getting confused but thankuuuuu so much
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But lysosome developed as it is the pinched off trans golgi ...explain this...?
Thank you for the easy lecture ......
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Wow you explained really well! Thank you so much!
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Thank you for great explanation!
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Concept clear thank you sir
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Thank you so much!
Well integrated.:)
Thanks thanks thanks a lot sir for this great explaination..... U r awesome..... Life saver.
hey I've got that book!!!
Molecular Biology of the Cell Fifth Edition by Alberts
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Thanks Suman, very useful
Thank you sir
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Perfect explanation!!
Thank you so much! :)
the image is blurred:(
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Thank you !! That was a perfect explanation. :D
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thank you very much
Endosomes and endocytic vesicles are same ?
can you teach me in detail about endosome ?
No
I have a question about endosomes.
Can you find there a membrane protein that’s on its way to the membrane? I mean after it’s synthesized and it’s ready to head to the membrane . And what is the journey this protein has from the cell to the membrane (what organelles does this protein have to go through in order to get eventually to the membrane)?
Actuall I couldn’t find much information about endosomes on google ..
What is a multivesicular body?
Could you explain for me the arrows from the late endosome ưhich then fuse with autophagosome/phagosome to make lysosome please ? By the ưay, your video is very comprehensive, thanks
Thankew sir ..
You're welcome
Can you teach about phagocytosis
Thanks realy good video
+konos alex thank you
Thanks dude!
thank you !
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So the lysosome comes from the endosome?
Very helpfull , Thank you :D
+Mouheb Salah you're welcome
What is heterophagosome?
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THANK U
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Thanks
Sir i have a doubt can u plz clear it.? What is the difference between phagosomes and phagocytic vesicles?? Are they the same thing ?? Plz help 🙏
If the vesicle is large (>250 nm in diameter), the method is called phagocytosis (cell eating), and the vesicle is a phagosome. If the vesicle is small (
The eaten vesicles is phagosomes and the draken vesicles or fluid substances is called phagocytotic vesicle
cool
ty
Thanks bro
Thanks,
What is this book please? 😐
Alberts...cell n mol biology
I thought Golgi make lysosome?
+Sia It does ish. So the TGN (Golgi) makes the enzymes, which fuse to the late endosome. The late endosome is not yet acidic enough to activate the hydrolases, but when it does become acidic enough, the late endosome morphs to a lysosome, and all of the M6P/other components of the original TGN clatherin vesicle are degraded.
Actually, no, even the early endosome has a PH of 6,2, which is enough for activation of hydrolases.
I thought lysosomes were organelles that digest material by fusing with endosomes. Why am I now seeing it as if endosomes become lysosomes themselves.
@@menace1782 Man we are all so lost
late endosome get more acid hydrolases from rough ER through trans golgi bodies and formed lysosome.