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- Опубликовано: 2 ноя 2024
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0:26 Does tumor size correlate to Gleason grade?
3:14 Are targeted biopsies still necessary for large tumors?
4:38 Does the tumor's relative location on the prostate matter?
7:17 Alex's conclusion
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Lord you folks are a god send. Thank you.
Thanks for another informative dialog
52 year old male, have been on finesteride for the past 26 years for male pattern baldness, came off finesteride (5mg 1/4 daily) in March, psa went from 2.6 to 4.5 in 14 weeks, free psa % was 12.6%.
Had an MRI 1 week ago, a 5mm lesion was identified with a PI RAD = 4 score.
Urologist recommending a biopsy.
Could this lesion have been in my prostate for a number of years whilst on finesteride and it has now become more aggressive from ceasing the 5 alpha blocker?
I was on Finasteride for 10 years for the exact same issue. I stopped taking it about 17 years ago and have recently had urinary issues. Went to the doc and he did a psa test. PSA came back at just under 10 so he ordered another one to be done a few weeks later to rule out infection. That one came back at just over 14. I think I screwed myself by taking that damned drug for hairloss.
I am told i have T2 Prostate Cancer. I was first diagnosed July 2019. My P.S.A. reading is currently 4.3. Please can you tell me what T2 means.
clinically very relevent as usual , tks
Excellent, I'd love to hear of the relationship of PSA results and risk, for instance a PSA of 12, vs 24, vs 55.... I'd love to hear about immune system (T-cell) targeting. Yes, the prostate resist them but I've read that very low carb with glutamine blockers, unlock the gates, so to speak allowing T-cells onto their target... That just sounds elegant much like the way 5-f or imiquimod works on BCC or SCCs.
Targeted Biopsy is good, but in my case I had also the pattern biopsy. So the target one was 8 cores and a few with cancer, but a couple of the pattern cores come back +'ve as well. So that changes the entire game, because it's the difference between one tumor in one place vS one big an obvious one + a couple waiting in the wings to take over once you treat the first.
Hi Alex and Doc S. Thanks for all the great info. Can you please do a video on Actinium-225. It has now become available here in South Africa. Would like to hear Doc Scholz opinion on this treatment.
Absolutely! We are filming the video tomorrow!
@ThePCRI . Awesome! Thank you so much🙏🙏🙏🙏
How effective is the PSMA radioligand therapy (LU-177 radiopharmacutical)?
Thank you for sharing 💙
What about if you have criboform pattern? Do you still recommend radiation
Thank y’all…
I’m currently undergoing hormone therapy and schedule for radiation. I just had a recent blood test for PSA came back at 1.060 from 10.75. I’m wondering if I even need radiation treatment since my PSA has come down a long ways. Enjoy your videos, very informative. Thank you.
The hormone drugs alone did that? Wow. Is it true what I've heard guys say on hormone therapy that you lose all sense of interest in women/sex? I heard it described as walking by a beautiful woman who before would typically make you turn your head now have zero interest. I just can't imagine that feeling. 😛
@@smoknvader9127 Yes, so far it has been just hormone therapy and diet. I have reduced my Carbohydrate intake to less that 20 carbs a day. They say that prostate cancer needs glucose to live and grow. I hopefully am starving them. I have with the hormone therapy, had the side effects of hot flashes, itchy skin and no erections.
Did you do an MRI? I had a PSA of 4.2, did the MRI and found a single lesion that biopsied for mostly 3+3 but a tad 3+4. So, I've gone on a very strict plant diet only eating beginning at 2pm no later than 8pm for the same reasons you mentioned. The starving factor seems to really do wonders. I have probably only eaten maybe 30grams of sugar (that I know of) in the last 3 months. My doc says I'm fine with active surveillance but has sent me to various 'specialists' to get a feel for options should it become necessary. Thanks to these many Dr. Scholz videos I've truly felt like I know more than these guys who only seem to know what they do - not to mention they clearly have financial interests in promoting their side. And 'their' side I mean surgery. No way. They don't have to live with the consequences. But the response is why risk it? BECAUSE you don't have to live with the consequences. But what I find very interesting so far is the complete lack of interest by these 'experts' in HIFU. My journey so far into the prostate cancer world has been interesting to say the least. Just how fragmented it is in terms of what exactly the 'right' treatment is. You'd think these people who are highly trained would know. Luckily my primary urologist isn't a surgeon so is fairly agnostic and a straight shooter. But down here in the Hoag network (Newport Beach, CA) they just built a very nice brand new cancer center that I'm sure has large bills to pay and HIFU I'm also sure pays poorly compared to radiation/surgery. Dean Coontz, the author, was apparently a very big donor who lives not too far to the original construction of the site, but seems that money only goes so far. Dr Scholz mentioned in one of his videos that $ is an issue in recommendations and I have been on the lookout for it since. And, sadly, that's what I have been confronted with. Thank God for RUclips and our ability to research this stuff ourselves. I'm very interested to see my next blood tests after I get my late Oct genetic results. I'm going to do another PSA and with my diet and fasting routine, interested to see if it affected it all. Good luck to you and hopefully mother nature and her natural food cures work. The cancer centers don't get paid that way. With all the disgusting misinformation we were forced on Covid, I don't trust hardly anyone in the biz. @@rancancookcanoy9768
@@smoknvader9127 I had the biopsy which I had two 4+3 cores along with some 3+3. I had a nodule also that was T2b. I have had a CT scan, MRI and PET PSMA scan. The scan have shown that I do not have any cancer outside of the prostate. My urologist was recommending surgery, glad I found the Prostate Cancer Research Institute and their youtube videos. The sad part is you have to do your own research so you can make an informed choice. I know several guys who had the surgery who now must wear a diaper daily due to leakage and not much bladder control. I hope the diet and your approach goes well for you and you are able to get this resolved. I started radiation therapy on Monday. Will see how that goes. Take care. Thank you.
@@smoknvader9127- 4-3 is different than 3-4 also wether is aggressive malignancy from your biopsy also determines radiation and hormone therapy . I’ve had both and as of 3 months ago I’am cancer free but still on the hormone therapy for at least 3 more months . There’s hope out there , I’am proof. Good luck to you .
Just had my PMSA pet scan today after declining Nuclear Bone Scan several times (NHS in UK)
Saddened that at the end the Radiologist opened a draw full of biscuits(cookies) and said “help yourself” 🤬
Thanks for the good info
After an MRI pelvis w wo contrast with a suspicious PIRADS 3-4 found, would you recommend as the report states an image guided biopsy or go straight into removal of the PROSTATE?
Do the biopsy and as Dr Scholz always says in his vids, try not to think about removal. The science and tech is moving so fast that it feels like we're literally weeks away from some kind of breakthrough. Just consider this - as little as 5 years ago Gleason 6s were being treated as aggressive tumors. It reminds of that scene from Star Trek 4 where they come back to our time and Doc is walking through the hospital in San Fran and is shocked by the Medieval medicine standards compared to his. (300 year difference though). PIRADS is a subjective suggestion by a viewing doc, NOT affirmed results. It's just his opinion looking at the MRI that the risk of something being there of significance needs to be investigated further. My MRI led to PIRADS 5, which led to the biopsy to confirm, which turned out to be mostly a Gleason 6, not some major 9 or 10 like a PIRADS 5 suggested. Even my urologist said as much. Many biopsies that a fused over an MRI end up turning out to be nothing. The biopsy will tell the tale. Get the Gleason rank and go from there. A 3+4 or 3+3 could simply mean watch it. As Dr Scholz says over and over, G6s don't grow. Imagine all the guys that got theirs removed and didn't have to that now deal with pads and ED that will never be fixed. I know one and ain't going down that road.
@@smoknvader9127 thank you
@@smoknvader9127 genomic testing is very important. 3+3 and 3+4 can also have a more aggressive biology that should be treated early not AS.
@@johnk.5274 Yes. That's why I'm waiting to make a decision based on that result. I'm just stuck between HIFU - which I'm going to consult with an expert in that out of my network this week - vs SBRT. Even though mine is low grade I'm still leaning toward getting it dealt with. But NO on surgery. 5 years from now I think we're going to be looking back as that kind of suggestion being totally out of line
My husband was diagnosed last year with G6, and this year it spread to his hip bone, Not sure if the biopsy was wrong or what, we shall see@@smoknvader9127
If you’ve had a 3T MRI and it didn’t indicate spread but did say it was a 4/5 mri aggressive grade. What are the chances it has spread?
Tumor genomics will give you information on the likelihood of spreading. Tests like Decipher, Oncotype Dx, Polaris can be requested by your doctor. The MRI grades are likelihood of abnormality being a cancer vs prostatitis, infection etc
@@johnk.5274 4K score I took and Epi. I’ll take a look at those . Thank You so much!
A PSMA pet scan is currently the most reliable test for determining prostate cancer metastasis.
I am a Gleason 6 ) 3+3 can I still use testosterone,I am 63 and have use it fir 15 years.