Curtain Raiser 10 - Azoospermia (Part-1) By Dr. Prof. (Col) Pankaj Talwar, VSM

Curtain Raiser 10 - Azoospermia (Part-1) By Dr. Prof. (Col) Pankaj Talwar, VSM
An interactive video lecture series: Curtain Raiser meant for IVF Doctors, Clinicians, Endocrinologists, Reproductive Medicine Specialists, Embryologists By IVF Specialist - Dr. Prof. (Col) Pankaj Talwar, VSM
𝐀 𝐂𝐨𝐦𝐩𝐫𝐞𝐡𝐞𝐧𝐬𝐢𝐯𝐞 𝐆𝐮𝐢𝐝𝐞 𝐭𝐨 𝐀𝐳𝐨𝐨𝐬𝐩𝐞𝐫𝐦𝐢𝐚
Azoospermia is a medical condition that affects men,
• leading to the absence of sperm in their semen.
• can cause infertility
• make it difficult for men to conceive with their partners.
𝐎𝐛𝐬𝐭𝐫𝐮𝐜𝐭𝐢𝐯𝐞 𝐀𝐳𝐨𝐨𝐬𝐩𝐞𝐫𝐦𝐢𝐚
Obstructive azoospermia occurs
• Due to a blockage in the male reproductive tract
• prevents the sperm from reaching the semen.
• The blockage can occur anywhere along the reproductive tract, including the epididymis, vas deferens, or ejaculatory ducts.
• The most common cause of obstructive azoospermia is a vasectomy, but it can also occur due to infection, trauma, or congenital abnormalities.
𝐓𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭 𝐎𝐩𝐭𝐢𝐨𝐧𝐬 𝐟𝐨𝐫 𝐎𝐛𝐬𝐭𝐫𝐮𝐜𝐭𝐢𝐯𝐞 𝐀𝐳𝐨𝐨𝐬𝐩𝐞𝐫𝐦𝐢𝐚
• Microsurgical Epididymal Sperm Aspiration (MESA)
• Percutaneous Epididymal Sperm Aspiration (PESA)
• Testicular Sperm Extraction (TESE)
• Testicular Sperm Aspiration (TESA)
• Micro-TESE
𝐍𝐨𝐧-𝐎𝐛𝐬𝐭𝐫𝐮𝐜𝐭𝐢𝐯𝐞 𝐀𝐳𝐨𝐨𝐬𝐩𝐞𝐫𝐦𝐢𝐚
Non-obstructive azoospermia occurs
• due to a problem in the testicles
• prevents them from producing enough sperm.
• This can occur due to a hormonal imbalance or a problem with the Leydig or Sertoli cells in the testicles.
• Non-obstructive azoospermia can also occur due to genetic abnormalities, such as Klinefelter syndrome.
𝐓𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭 𝐎𝐩𝐭𝐢𝐨𝐧𝐬 𝐟𝐨𝐫 𝐍𝐨𝐧-𝐎𝐛𝐬𝐭𝐫𝐮𝐜𝐭𝐢𝐯𝐞 𝐀𝐳𝐨𝐨𝐬𝐩𝐞𝐫𝐦𝐢𝐚
• Hormonal therapy to balance FSH, LH, and testosterone levels
• Surgical Sperm Retrieval
• Intra-Cytoplasmic Sperm Injection (ICSI)
• Causes of Non-Obstructive Azoospermia
• Testicular Failure
• Genetic Abnormalities
• Hormonal Imbalance
• Varicocele
𝐒𝐮𝐫𝐠𝐢𝐜𝐚𝐥 𝐒𝐩𝐞𝐫𝐦 𝐑𝐞𝐭𝐫𝐢𝐞𝐯𝐚𝐥
• Surgical sperm retrieval is a procedure that involves obtaining sperm from the testicles or epididymis through a surgical procedure.
• This is typically done when the patient has non-obstructive azoospermia and has no sperm in their semen.
• The retrieved sperm can then be used for ICSI to fertilize the partner's egg.
𝐓𝐲𝐩𝐞𝐬 𝐨𝐟 𝐒𝐮𝐫𝐠𝐢𝐜𝐚𝐥 𝐒𝐩𝐞𝐫𝐦 𝐑𝐞𝐭𝐫𝐢𝐞𝐯𝐚𝐥
• Testicular Sperm Extraction (TESE)
• Testicular Sperm Aspiration (TESA)
• Micro-TESE
𝐕𝐚𝐫𝐢𝐜𝐨𝐜𝐞𝐥𝐞
• Varicocele is a condition that occurs when the veins in the scrotum become enlarged, leading to reduced blood flow to the testicles.
• This can cause testicular damage and lead to infertility.
• Varicocele can be treated through surgery or embolization, which involves blocking the affected veins.
𝐈𝐧𝐭𝐫𝐚-𝐂𝐲𝐭𝐨𝐩𝐥𝐚𝐬𝐦𝐢𝐜 𝐒𝐩𝐞𝐫𝐦 𝐈𝐧𝐣𝐞𝐜𝐭𝐢𝐨𝐧 (𝐈𝐂𝐒𝐈)
• ICSI is a procedure that involves injecting a single sperm directly into the partner's egg, bypassing the need for the sperm to reach the egg on its own.
• This procedure is commonly used in cases of male infertility, including azoospermia, to increase the chances of fertilization.
𝐅𝐞𝐫𝐭𝐢𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐅𝐚𝐢𝐥𝐮𝐫𝐞
• Even with ICSI, fertilization failure can occur, which means that the injected sperm fails to fertilize the partner's egg.
• This can occur due to a variety of factors, including the quality of the sperm or egg, or problems with the fertilization process itself.
In conclusion, azoospermia is a condition that can lead to infertility in men, making it difficult for them to conceive with their partners. The condition can be caused by obstructive or non-obstructive factors, with treatments varying depending on the type of azoospermia.
𝘿𝙤 𝙡𝙚𝙖𝙫𝙚 𝙮𝙤𝙪𝙧 𝙘𝙤𝙢𝙢𝙚𝙣𝙩𝙨 𝙝𝙤𝙬 𝙙𝙞𝙙 𝙮𝙤𝙪 𝙛𝙞𝙣𝙙 𝙩𝙝𝙚 𝙨𝙚𝙨𝙨𝙞𝙤𝙣 𝙖𝙣𝙙 𝙥𝙡𝙨 𝙛𝙚𝙚𝙡 𝙛𝙧𝙚𝙚 𝙩𝙤 𝙡𝙚𝙖𝙫𝙚 𝙮𝙤𝙪𝙧 𝙦𝙪𝙚𝙧𝙞𝙚𝙨 𝙧𝙚𝙡𝙖𝙩𝙚𝙙 𝙩𝙤 𝙩𝙝𝙚 𝙩𝙤𝙥𝙞𝙘.
You can watch the Part -2 of this Curtain Raiser - 10 here: • Curtain Raiser 10 - Az...
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