It is not easy to accurately summarize another person's words and thoughts, especially when it applies to such a complex discipline like medicine. Well done!!!
I was insulin resistant and wore a glucose monitor. Gaining access to one largely depends on your healthcare provider, and whether or not they accept insurance. This was a great video. Thank you for taking the time to put it together.
I really needed this. I love the book, but many people in my life, who need it, will simply not read it. I do hope they can get trough this excellent summary. You rock!
2:45 As I’m reading it, they had to consume >= 4 Tbsp per day(0.4 L) of olive oil, but they were provided with 15 L per 3 months to account for the family’s needs (so make sure they had an adequate supply of olive oil). 1L per week of olive oil would equal about 8500 calories per week, …even the 4 Tbsp amounts to about 3400 calories per week of just olive oil.
@TSLApilot I've heard Steven Gundry say it was 1 liter of olive oil per week many many times and I just took it for granted. Thanks for bringing that up.
@@lovesense7246 as a physician, I’m skeptical of many things I’ve heard from Gundry. Attia is more evidence based. I do very much appreciate your summary.
Regarding the case of the guy who "cured" himself with fasting: If you have severe cancer, losing muscle and testosterone isn't a huge issue, as your priority is immediate survival. If there is no immediate threat to fix, it MAY be a better idea to have the muscle mass and robustness associated with protein intake and not regularly fasting. This could protect you against other future threats, as well as increasing quality of life. Attia's recommendations aren't necessarily about living the longest possible life to the last second, but living the longest healthy, rewarding life.
What a great video, I loved the book and this summary is easy to understand for people like me who don't have a great understanding with the technical pionts in Peter's book
23:30 Sinclair refers to studies that combine both unhealthy animal diets (burgers, bacon, etc) and healthy diets (salmon, etc), so no conclusions can be made about healthy animal diets Gundry supports intermittent fasting, which Attia supports. He cautions against overconsuming protein, but Attia doesn't recommend overconsuming protein
You are your own best health advocate. Eat a healthy whole food plant based diet, reduce stress, get adequate sleep and exercise regularly. Every adult and child should own a bicycle and ride it regularly. You will be healthier, happier and have lower transportation and health care expenses. Make a bicycle your first choice for short distance travel.
The research on lifespan and consumption of protein is mixed. The research on healthspan and consumption of protein/muscle growth is extremely clear. If you want to have as long of a healthspan as possible and live an enjoyable life into your 80s and 90s, you will need the excess muscle tissue and training of those muscles to maintain your mobility into your later stages of life. I've found that Peter is much more thoughtful about the balance between healthspan and lifespan than most other people in the longevity space which is what has led him to different places than others.
The way I thought of it is, people who are mentally sharp have a good grip strength, but it not because they train handmuscles, it's because of overall muscularity which leads to a higher grip strength. One can't just train hands and stay sharp
As I was listening to your summary of the book there were red flag that my institution said that doesn’t feel right to me and all the research I have done . I am a firm believer. You take what you need only the rest there… I was pleasantly surprised to see that at the end of this video, you have the same thoughts as I did… Yes, I’m grateful that the book was written, and I may check it out… But I agree with all your comments at the end.
A majority of the studies I've come across indicate caloric restriction in general improves lifespan, which is not specially limited to a fasted application. Especially intermittent fasting which Attia has said in several podcasts, doesn't take advantage of cell autophagy. Which is the main known benefit of fasting.
@prslespaul In mice...increased lifespan in mice. Jury is still out about consistent CR in humans, over time - not discernible in humans.. for obvious reasons 🙄 Yah, interesting that SO many, including some doctors and med clinicians, tout IF as if it were a long enough fast to even begin an autophagenic state. Turns out...most seem to be practicing IF under a delusion of autophagenic benefits😆
Great you pointed out the high protein contradiction, also worth mentioning that Dr. Valter Longo, who pioneered the research on fasting (and FMD) in cancer patients, recommends the opposite of Peter's advice. As much as I love Peter and his work, he's a passionate hunter and lifter, so there is clearly some confirmation bias here. He has a lot of personal reasons to eat high amounts of animal protein, and he wants to hold on to extra amounts of muscle that's not required outside of the gym.
I was listening to PA's podcast with Dr. Don Layman, who is, as well as PA adamant about protein. It is essential for people over 65, moreover, a vegan diet can be made in a way to provide enough dietary protein but it would require people to eat around the clock, as veggie protein is only 50% adaptable to our body needs. I also would like to point out that PA changed his outlook on fasting not because he is a passionate hunter, but because he is a practicing longevity doctor and he actually sees patients on a daily basis, and the majority of them can not liver good lives not because they eat much, but because they lack lean muscle mass because of sarcopenia! Fasting causes it big time With all the fasting that he did in his life, I'm sure he could weight all the pros and cons correctly. So - before the age of, say 45 - it's more or less OK to fast, later - you'll see your quality of life decline proportionately to a lean mass decline.
Fasting correlates with longer lifespan, not healthspan. Peter is much more cognizant of the balance between the two than most other people in this space, and high protein/muscle growth and strength training all highly correlate with long healthspan.
@@lovesense7246 I already shared it with my family and friends, many whom I don’t expect to read the book but will listen and enjoy your summary, which is exactly of the right length and content: not too short and not too long, and honest! And of course, I subscribed to your channel to learn more meaningful things! Thank you so much!!
Yup. I hear saunas are very accessible in Finland, the happiest country in the world. I love Finland and the other nordic countries! Why did you end up moving?
@@abdelilahbenahmed4350hat sort of ridiculous comment is that after asking for a source to his information. You’re reply to him giving this sounds like something a child would say 😂 I’d say happiness is pretty high up on any persons list. You must be the life and soul at parties!
Thanks for this great video! I am a bit confused about what to do because of the two schools of thought when it comes to protein intake. I read Dr Valter Longo's book two years ago who says too much protein is bad (but he also says after age 65-66 we need more protein) and now I am learning about Dr Attia's ideas.
Thank you for the good points in the book you appreciate! I guess people have a lot of backround noise in their lives now, so you put background noise in your video. I find the noise irritating, but it seems to be the new trend on RUclips.
I did try to get through Attia's audiobook but as many, many people have said the book is overly long and jumps all over the place trying to cover all possible bases in order to support his own view of himself as a leading authority on everything. You have only confirmed my own and others' opinions on this book and the good doc. Another RUclips legend who crowned himself king.
Attia emphasizes quality of life in addition to length of life, which is why he supports protein intake and keeping muscle mass as you age, whereas others looking solely at length of life do not emphasize eating meat, etc. I think there's a small trade off Attia is aware of that length of life could be kept the same but at the cost of additional effort of exercising vigorously and keeping muscle to avoid accidents and general feebleness. I hope this explanation makes sense.
Grip strength is a convenient proxy for the overall muscular body strength. It can be easily measured in the doctor's office with an inexpensive tester. Unlike, say, leg strength. The idea, is that strong muscles promote health & lifespan.
In predimed trial the low fat diet was not mediteranian. It was AHA recommended diet. And it turned out not to be low fat it had 37% calories from fat which is higher fat than average american diet that has 35% of calories from fat.
Petter is huge on protein/amino acids but takes rapamycin to inhibit mTor for longevity. I guess it’s up to one to decide how much muscle/gain can be traded for autophagy
Grip strength alone is a signifier for your mind muscle connection and therefor a good and easy indicator for your fitness. Don't confuse this for the causation. People who work manually, typically have great grip strength values. But it is the physical work and movement- often outside- that keeps them young and fit. Training your grip strength alone does not hurt, but it is a big problem of the longevity movement to manipulate biomarkers, using supplements that move them, instead of treating the cause of that set biomarker: E.g. if you only train your grip strength and do cardio, you will look great on certain tests because they feature a those exactly. Still you need to do real training and physical labour along with maybe some complicated movements, that challenge neuroplasticity like playing an instrument to really prevent the degrading of that part of your brain.
The problem with extended fasting is its implementation in the general population. The benefits of "daily fasting" by skipping breakfasts are similar to caloric restriction, so take your pick. Only a few people are willing to choose 3+ days without eating for the additional benefits. Doing an extended fast safely and effectively is another discussion. The downside of extended fasting is hypoglycemia, gallstones, osteoporosis, increased stress, social isolation, eating disorders, and more. You don't often hear about those. Also, a large subset of the population is overweight and malnourished simultaneously. They need to both decrease calories and change to healthier foods. You set them up for success by making a variety of small habit changes over time.
You have to gradually build up your fast, like with anything. Like if you go to the gym, you don't go off with the most amount of weight, you'll most likely snap something.
I'm pretty strongly on Peter's side here, as I find the fasting research to be pretty unconvincing because of all the confounding variables. Kind of how we're finding out that IF has no real benefit over caloric restriction, I think we're going to find similar things with fasting research, that the difference in impact is due to other factors like, people willing to fast for extended periods of time are more likely to be thoughtful about their health in ways that are difficult to control for in a trial.
You make it sound like Peter Attia promotes a specific diet or food in the book outlive. For nutrition Peter Attia states that the studies on nutrition are confounded and don’t even show great changes in the hazard ratio. At end of the chapter he suggests that if he did not mention your special diet or food, it is better to get out and exercise.
Outstanding synopsis of Peter Attia’s book “Outlive”! Your technique is most appealing ! Your take on analyzing what bothers you about the book is most helpful! Grateful to you! Looking forward to more reviews! Have you done “Life Span”?
@tallybrillembourg6211 Thank you for the positive comment! So happy you liked it! Lifespan animated book summary here: ruclips.net/video/3GSN9IbTK3I/видео.html
Thanks for this summary! I agree with his not mentioning the Blue Zones. I also think that his exercise recommendations are a bit extreme, ie, >37 hours total in a week!
The difference between Peter and others about protein can be because Peter, I feel, gives importance to the healthspan and this includes having a sound body. As he says being "a kickass 90 year old" and being able to play and throw your grandchildren. Now you don't necessarily have a broken body if you don't, but odds increase by far. I also agree it's not worth the risk and having higher life quality is sometimes more important than living longer. Edit: He discusses the tradeoff here as far as I can remember ruclips.net/video/BqmG2y4IeY8/видео.html
9:25 Importance of good sleep 11:20 Preventing cancer 14:00 Fasting and Immunotherapy 16:55 Glucose monitoring 18:00 Stability 21:00 Metformin 21:30 Fasting-Protein is the most important macronutrient 22:40 Animal protein can be problematic
You should further check the types of proteins David and Steve talk about. Animal protein is not something those authors promote. In fact, you can go with proteins from legumes, fruits, and vegetables while minimizing the amount of animal proteins, and still consume optimal levels of protein.
@@lovesense7246 Here is just one opinion. runway.airforce.gov.au/resources/link-article/dr-saul-newman-debunking-blue-zone-longevity-myth#:~:text=A%20study%20by%20Dr%20Saul,have%20claimed%20higher%20longevity%20rates.
@@lovesense7246 I just went to your page, love the fact you are researching many different opinions. When you go down the rabbit hole of nutrition, health and wellness there is a whole plethora of different opinions. But for me it is ( n=1 ) We are all an experiment of 1. what works for me may not work for you and vice versa. To your health! Cheers
Great summary. Haven’t read the book but I’m very familiar with Peter Attia’s perspectives. Interesting that he left off the blue zones and find the fasting/blue zone/mtor/rapamycin stuff conflicting. I tend to think some mild fasting AND a little more protein is probably the best combo as one ages.
It is unfortunate he doesn't talk about the Blue Zones as they have the key to Longevity and there is an evidenced based book which found that the drinking water in these areas is rich in Silica. Silica is essential for life and protects us from a neurotoxin aluminum which we are exposed to daily. The book is Silica Water the Secret to Healthy Longevity in the Aluminum Age by Dennis N Crouse. Here is a link to write up at his blog about a 6th blue zone he researched after seeing an exhibit at the Boston Museum of Science. He has a website, you tube channel, blog on blogger. Dennis is a chemist and has developed a recipe for making your own silica water, Silicade. He has anecdotal information about improvements people have seen from drinking silica rich water. prevent-alzheimers-autism-stroke.blogspot.com/2019/07/sixth-blue-zone-west-hechi-china.html
@fizywig nope - actually strength training, especially, opens the mTOR pathway, for muscle protein synthesis, in and of itself. Also, gluconeogenesis occurs in the liver pretty much on a constant basis. The idea that 'too much' or 'high protein' promotes increased gluconeogenesis, is untrue.
I have the book now, from the library, after a long wait. You got more out of it than I did - I'll try harder! I especially appreciated the sections on exercise and stability. I also was confused by the section on fasting, intermittent fasting. I have also learned to trust Roger Seheult at Medcram during the last 3 years.
Regarding Keto: Is not what Peter recommends. He has said and written, that Keto is not sustainable. He does recommend to have a good quality source of protein. You need to get those facts right.
@@peterfrancisharrishe said in a podcast episode that it was not sustainable for him. He ate Keto for three years but said he could not do it again for a significant amount of time.
Saturated fat may cause apoB counts to rise which is a risk factor for coronary artery disease. Can you please double check your information since you reported it was the rise in triglycerides that is bad for the heart. apoB particle count is more relevant to cardiovascular disease risk than serum triglycerides, generally speaking.
People like Dr Shawn Baker say that the Triglycerides/HDL ratio is the most important, and that it should be less than 2. If that is so it means that even if your LDL levels are high, the it would possibly be the Large Buoyant type LDL, which is not detrimental to cholesterol oxidation which is the chief cause of arterial plaquing. While I do admire and respect Dr Attia, his sudden U turns on fasting, and Keto diets, makes me suspicious of the sudden hullabaloo on APO B
@@pardogg "My first step in controlling my own cardiovascular risk was to begin to change my own diet, so as to lower my triglycerides (a contributor to apoB when they are high, as mine were), but more importantly to manage my insulin levels. I needed to get my metabolic house in order. I should note that my own solution at the time, a ketogenic diet, might not work for everyone, nor is it a diet to which I continue to adhere. In my clinical experience, about a third to half of people who consume high amounts of saturated fats (which sometimes goes hand in hand with a ketogenic diet) will experience a dramatic increase in apoB particles, which we obviously don't want. There are at least two reasons for this. First, it seems saturated fat contributes directly to the synthesis of excess cholesterol. Second, and more importantly, excess saturated fat causes the liver to reduce expression of LDL receptors, thereby reducing the amount of LDL removed from circulation." Peter Attia, Outlive (pg. 133) You were right! My memory failed me at the time of writing the script... sorry about that!
There is no study demonstrating that animal protein in isolation is linked to shorter lifespan. It is silly to come to the conclusion that "This person ate more meat and had cardiovascular issues therefore meat is the problem". The majority of the meat consumed in industrialized countries is factory farmed and loaded with saturated fat and preservatives. Attia is spot on with this topic. Add clean protein and exercise to utilize it properly. Do not avoid animal protein due to an incorrect fear it is dangerous, just be selective with the sources.
thanx!!! + really GREAT 👍🏻 that you keep being sceptical/critical!…. (cos me too i think fasting helps a lot cod of autophsgy and too much protein = silly)
man the first couple of mins of this video is not my key takeaways from the book at all. sure he talks about keto but that's in relation to one of the "four horsemen" (metabolic dysfunction,) and also on how that type of diet may be useful when combating neurogenerative disease. also, the bit on flossing and sauna are correlated but not causal. (eg like the bacteria found in the mouth related to gum disease has also been found in folks with dementia in larger numbers than those without gum disease, but in the book he admits the relation is still unclear)
Is everyone not seeing the forest for the trees? Alzheimers AND foul teeth are caused.... BY CARBS. It's is completely obvious that people with rotten teeth also have Alzheimers, because both have the same root cause.
Thanks for the summary. On the ending, that whole topic I think is legitimately up for debate and is not settled, that's why it's confusing. One side will say that we have rat studies where high protein levels are bad, the other will say in that same study a combination with high protein was longest lived. One side will say blue zones, the other side will say most blue zones likely exist due to welfare fraud rather than actually longer lifespan. One side will say human correlational studies show high protein is bad, the other side says those are just correlations and are likely picking up confounds, etc etc. Fwiw how I'm practically thinking about it: all else equal less calories is obviously good, fasting per se is probably good for cancer treatment and maybe cancer prevention, the biggest downside is muscle loss which is important so if you are at risk of sarcopenia or could just use more muscle I would focus on that over fasting
excellent video, I found it really interesting. Though I will say that oftentimes I wonder if correlation and cause were confused. For example, how do you get a lot of grip strength? By working out, by actively building something with your hands etc. Maybe its just that people who do this, will not get neurodegenerative diseases. Because I doubt that artificially training grip strength with a specialized machine will make your brain function much better.
First of all, Attias Book is very good and your summary is pretty much on point. Besides that, Steven Gundry is a con. Don't even consider whatever he says. Sinclair is not a con, he is probably a good researcher on his field, but nutrition is NOT his field. His point of view on animal protein is garbage because he is basing this almost entirely on animal studies that simply cannot refer to humans. Mices are omnivores with a very clear and big focus on plant based foods. Humans evolved on meat and became the biggest and by far most skilled hunters on the planet. And humans don't live in a lab with full time care and in a germ- and stress-free environment. There a no mechanistic human studies that show animal protein could be harmful for us. The only human studies he refers to are epidemiological and basically show nothing. However, there are tons of studies that show plant based diets can harm us. Sinclair also said, that "when you eat is far more important than what you eat" - and that's probably the dumbest and worst nutritional advice I've ever heard of.
@12:37 per David Sinclair, it's actually not the AMOUNT of food they ate or that you eat, but the longevity is from eating at one time each day, which means you're not eating for all the rest of the day. actually the longevity effect occurs due to genes turned on after about 8-12 hours of not eating, genes which cause cellular autophagy; a general repairing and clean up mechanism. in theory, you can actually eat 3 meals in 1 if you do it all in 1 hour's timeframe per day and get the same effect, so technically to say "if you eat less" is incorrect
You forgot to mention the top gerontologist in US who has done most of the research on fasting and fmd creator Valter Longo PhD as well as Mark Mattson who ignite the " Intermittent Fasting" thing and did a lot of research on fasting and brain at John Hopkins Medical school, they advise against high protein diet ... you can read more about Valter Longo in his book " The longevity Diet"
I think what’s confusing about peters fasting recommendation is that he fasts himself. He should signal what he actually does to ensure he meets his nutrients
@21972012145525 No, he does not fast - to atophagy - any longer. He assessed, at some recent point, over a year's time that his periodic fasting sessions (1x/quarter,I believe) promoted an increase in muscle loss, despite his doing everything correctly with his diet and strength training to promote, or at least maintain his muscle mass. As a result, he no longer fasts. He's changed his educated opinion on fasting, as he has, as well, on some other supposedly beneficial health practices - such as taking Metformin prophylactically - which he was taking for perceived health benefits, as per some - or an initial study. But with recent study findings on prophylactic use (or off-label usage) of Met. where those initial findings have been reversed, or at least negated, Dr. Attia hss reversed his opinion of taking Metformin prophylactically and no longer takes it. That's what I respect and admire about Dr. Attia - and why I follow him, trust his educated opinion(s). He us not one to doggedly stick with his initial findings (educated opinion) on health practices , etc. As emerging study findings change, so does his opinion on the subject. Not at all afraid to reverse himself about anything he previously may have endorsed at one time. . Best way to be assured, in my pov, that the man makes a concerted effort against entertaining a bias that may turn out to be incorrect. Love ❤️ that about him!
I’ll definitely consider it. Last week, my dad was telling me about a book called the testosterone advantage that changed his life many years ago, and that that should be the book I review next.
The Blue Zones thing is a bluff. Sardinia is one of them and it is qlso a European region. According to official statistics from Eurostat (the UE statistics agency) it don't even make the top ten among the European Regions in life expectancy indicators
Thanks for the summary, it sounds like I can skip this one. As you point out Peter has a number of rather odd views on things, which the more credible sources go against. I would recommend How Not To Die, for fact based nutrition, which is really the core of it.
Sorry, How Not To Die author, Dr, Gregor is a shill for the Peta crowd, a major source of his income. Hence, all the plant-based "science" which is highly cherry-picked and very low credibility.
It is not easy to accurately summarize another person's words and thoughts, especially when it applies to such a complex discipline like medicine. Well done!!!
Thank you!!!
It was done with Artificial intelligence lol
I was insulin resistant and wore a glucose monitor. Gaining access to one largely depends on your healthcare provider, and whether or not they accept insurance.
This was a great video. Thank you for taking the time to put it together.
Some countries don’t even require you to have a prescription to buy one. I later found that out…
This is an excellent video and summary of Outlive. Thanks for doing it.
Glad you enjoyed it!
I really needed this. I love the book, but many people in my life, who need it, will simply not read it. I do hope they can get trough this excellent summary. You rock!
@maya8792 Thank you so much for the comment! Glad you liked it!
Yes, we need to get peoples heads out of the sand. It’s not easy denial deception delay the three D’s😢
Great summary thanks I love people like you who do some videos that I can send to friends and family that will never actually read the book, cheers
Thanks! Hope your friends and family like it!
This is brilliant! Thank you for your effort making this video!
You’re welcome!!
High value video bro. Good job.
Glad you liked it! Thank you!
2:45 As I’m reading it, they had to consume >= 4 Tbsp per day(0.4 L) of olive oil, but they were provided with 15 L per 3 months to account for the family’s needs (so make sure they had an adequate supply of olive oil). 1L per week of olive oil would equal about 8500 calories per week, …even the 4 Tbsp amounts to about 3400 calories per week of just olive oil.
@TSLApilot I've heard Steven Gundry say it was 1 liter of olive oil per week many many times and I just took it for granted. Thanks for bringing that up.
@@lovesense7246 as a physician, I’m skeptical of many things I’ve heard from Gundry. Attia is more evidence based. I do very much appreciate your summary.
4 tablespoons a week is 480 calories
@@stargazerbird I meant 4 Tbps per DAY not week. I corrected my post.
Regarding the case of the guy who "cured" himself with fasting: If you have severe cancer, losing muscle and testosterone isn't a huge issue, as your priority is immediate survival. If there is no immediate threat to fix, it MAY be a better idea to have the muscle mass and robustness associated with protein intake and not regularly fasting. This could protect you against other future threats, as well as increasing quality of life. Attia's recommendations aren't necessarily about living the longest possible life to the last second, but living the longest healthy, rewarding life.
👍 Agree!
Exactly: building body vs building longevity
What a great video, I loved the book and this summary is easy to understand for people like me who don't have a great understanding with the technical pionts in Peter's book
Glad you liked it!
Great job--love the summary of Peter's book.
Thanks! So glad you liked it!
23:30 Sinclair refers to studies that combine both unhealthy animal diets (burgers, bacon, etc) and healthy diets (salmon, etc), so no conclusions can be made about healthy animal diets
Gundry supports intermittent fasting, which Attia supports. He cautions against overconsuming protein, but Attia doesn't recommend overconsuming protein
You are your own best health advocate.
Eat a healthy whole food plant based diet, reduce stress, get adequate sleep and exercise regularly.
Every adult and child should own a bicycle and ride it regularly. You will be healthier, happier and have lower transportation and health care expenses. Make a bicycle your first choice for short distance travel.
love those dudes and girls who take the car to the gym, while they dont even life that far away
Thank you so much for this resume
You're welcome!
The research on lifespan and consumption of protein is mixed. The research on healthspan and consumption of protein/muscle growth is extremely clear. If you want to have as long of a healthspan as possible and live an enjoyable life into your 80s and 90s, you will need the excess muscle tissue and training of those muscles to maintain your mobility into your later stages of life. I've found that Peter is much more thoughtful about the balance between healthspan and lifespan than most other people in the longevity space which is what has led him to different places than others.
Thank you! very insightful and the information is well sectioned
Glad you liked it!
Love your summaries. Looking forwar to the next videos 😍
Thank you! More on the way!
The way I thought of it is, people who are mentally sharp have a good grip strength, but it not because they train handmuscles, it's because of overall muscularity which leads to a higher grip strength.
One can't just train hands and stay sharp
Yes that makes sense
As I was listening to your summary of the book there were red flag that my institution said that doesn’t feel right to me and all the research I have done . I am a firm believer. You take what you need only the rest there… I was pleasantly surprised to see that at the end of this video, you have the same thoughts as I did… Yes, I’m grateful that the book was written, and I may check it out… But I agree with all your comments at the end.
Amazing summary, thank you.
You’re welcome!
A majority of the studies I've come across indicate caloric restriction in general improves lifespan, which is not specially limited to a fasted application. Especially intermittent fasting which Attia has said in several podcasts, doesn't take advantage of cell autophagy. Which is the main known benefit of fasting.
@prslespaul
In mice...increased lifespan in mice.
Jury is still out about consistent CR in humans, over time - not discernible in humans.. for obvious reasons 🙄
Yah, interesting that SO many, including some doctors and med clinicians, tout IF as if it were a long enough fast to even begin an autophagenic state.
Turns out...most seem to be practicing IF under a delusion of autophagenic benefits😆
@@ezbrah_ derp...using common sense works very well when thinking about the issue of consistent fasting & CR.
Let's not forget mindfulness meditation. This book goes well along with the one titled "30 Days to Reduce Anxiety" by Harper Daniels.
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Thank you, appreciate your summary.
You’re welcome!
Your personal comments at the end of video (on what left you confused) was what I enjoyed best
Glad you liked it! Thank you!
Great you pointed out the high protein contradiction, also worth mentioning that Dr. Valter Longo, who pioneered the research on fasting (and FMD) in cancer patients, recommends the opposite of Peter's advice. As much as I love Peter and his work, he's a passionate hunter and lifter, so there is clearly some confirmation bias here. He has a lot of personal reasons to eat high amounts of animal protein, and he wants to hold on to extra amounts of muscle that's not required outside of the gym.
I was listening to PA's podcast with Dr. Don Layman, who is, as well as PA adamant about protein. It is essential for people over 65, moreover, a vegan diet can be made in a way to provide enough dietary protein but it would require people to eat around the clock, as veggie protein is only 50% adaptable to our body needs. I also would like to point out that PA changed his outlook on fasting not because he is a passionate hunter, but because he is a practicing longevity doctor and he actually sees patients on a daily basis, and the majority of them can not liver good lives not because they eat much, but because they lack lean muscle mass because of sarcopenia! Fasting causes it big time With all the fasting that he did in his life, I'm sure he could weight all the pros and cons correctly. So - before the age of, say 45 - it's more or less OK to fast, later - you'll see your quality of life decline proportionately to a lean mass decline.
Fasting correlates with longer lifespan, not healthspan. Peter is much more cognizant of the balance between the two than most other people in this space, and high protein/muscle growth and strength training all highly correlate with long healthspan.
Great summary and graphical presentation! I feel more prepared for my bookclub meeting today!
Excellent video summary. Thanks!
You’re welcome! So happy you liked it!
Saw an interview where Peter Attia said he doesn't do Keto anymore. For practicality reasons.
Yup. He mentions that in the book, but keto does have it’s benefits, although it’s definitely not for everyone.
Your triglycerides will not increase from saturated fat.
Your triglycerides will increase from eating an excessive amount of sugar and grains.
Yup. I made a mistake there. Addressed it in the description. Sorry about that.
Fantastic- that is a truly great summary!!
@@wowgetter thanks! Glad you enjoyed it!
@@lovesense7246 I already shared it with my family and friends, many whom I don’t expect to read the book but will listen and enjoy your summary, which is exactly of the right length and content: not too short and not too long, and honest! And of course, I subscribed to your channel to learn more meaningful things! Thank you so much!!
@@wowgetter thank you for sharing and subscribing! More videos coming soon!
A+ summary. Thank you for this.
You’re welcome! Glad you liked it!
Great review, thanks bro!
Thanks for watching!
Thank you for this video 🙌🏻
You’re welcome!
I hate the fact that now that I moved away from Finland, everyone says you should use Sauna.
Yup. I hear saunas are very accessible in Finland, the happiest country in the world. I love Finland and the other nordic countries! Why did you end up moving?
@@lovesense7246how do you know that Finland is the happiest country in the world?
@@abdelilahbenahmed4350 ruclips.net/video/6Pm0Mn0-jYU/видео.html
@@lovesense7246 happiness is not everything.
@@abdelilahbenahmed4350hat sort of ridiculous comment is that after asking for a source to his information. You’re reply to him giving this sounds like something a child would say 😂 I’d say happiness is pretty high up on any persons list.
You must be the life and soul at parties!
Just discovered your channel, you got really interesting topics. Keep going!!
Thank you! Will do!
my man!!
thanks for the always interesting content
Thanks for all the positive comments!
Thanks for this great video! I am a bit confused about what to do because of the two schools of thought when it comes to protein intake. I read Dr Valter Longo's book two years ago who says too much protein is bad (but he also says after age 65-66 we need more protein) and now I am learning about Dr Attia's ideas.
Glad you liked it! I don't think anyone truly knows the answer to that. We'll just have to wait and see!
Thanks for the summary
You’re welcome!
Thank you for the good points in the book you appreciate! I guess people have a lot of backround noise in their lives now, so you put background noise in your video. I find the noise irritating, but it seems to be the new trend on RUclips.
Awesome video! I’m reading his book now. Thanks.
Glad you liked it and I hope you enjoy the book!
Great job at summarizing such a complex book!
Glad you liked it!
I'm just reading the book but this your summary is cool as well. Thank you!
Thanks! Enjoy the book!
Thank you so much! Very informative!
You’re welcome!
Great summary ... of what turned out to be a very complicated protocol.
I did try to get through Attia's audiobook but as many, many people have said the book is overly long and jumps all over the place trying to cover all possible bases in order to support his own view of himself as a leading authority on everything. You have only confirmed my own and others' opinions on this book and the good doc. Another RUclips legend who crowned himself king.
Attia emphasizes quality of life in addition to length of life, which is why he supports protein intake and keeping muscle mass as you age, whereas others looking solely at length of life do not emphasize eating meat, etc. I think there's a small trade off Attia is aware of that length of life could be kept the same but at the cost of additional effort of exercising vigorously and keeping muscle to avoid accidents and general feebleness. I hope this explanation makes sense.
Thank-you GREAT REVIEW
So glad you liked it!
Grip strength is a convenient proxy for the overall muscular body strength. It can be easily measured in the doctor's office with an inexpensive tester. Unlike, say, leg strength. The idea, is that strong muscles promote health & lifespan.
I have attention deficit and find reading difficult. Thank you for this summary. Seriously
You're so welcome!
This is an amazing video! thanks :)
Glad you liked it!
In predimed trial the low fat diet was not mediteranian. It was AHA recommended diet. And it turned out not to be low fat it had 37% calories from fat which is higher fat than average american diet that has 35% of calories from fat.
CGM are avaiable without prescription, at least in Italy.
This was great. Appreciated!
Petter is huge on protein/amino acids but takes rapamycin to inhibit mTor for longevity. I guess it’s up to one to decide how much muscle/gain can be traded for autophagy
What does preventing mTor provide how is it beneficial to your health?
Grip strength alone is a signifier for your mind muscle connection and therefor a good and easy indicator for your fitness. Don't confuse this for the causation. People who work manually, typically have great grip strength values. But it is the physical work and movement- often outside- that keeps them young and fit. Training your grip strength alone does not hurt, but it is a big problem of the longevity movement to manipulate biomarkers, using supplements that move them, instead of treating the cause of that set biomarker: E.g. if you only train your grip strength and do cardio, you will look great on certain tests because they feature a those exactly. Still you need to do real training and physical labour along with maybe some complicated movements, that challenge neuroplasticity like playing an instrument to really prevent the degrading of that part of your brain.
That makes a lot of sense! Thank you for taking the time to explain that!
I'm 71 years, played guitar 60 years, now shredding. All I have left is my hands and my mind 😃
He says he's not into keto anymore in the book
Thank you for sharing ❤️
You’re welcome!
The problem with extended fasting is its implementation in the general population. The benefits of "daily fasting" by skipping breakfasts are similar to caloric restriction, so take your pick. Only a few people are willing to choose 3+ days without eating for the additional benefits. Doing an extended fast safely and effectively is another discussion. The downside of extended fasting is hypoglycemia, gallstones, osteoporosis, increased stress, social isolation, eating disorders, and more. You don't often hear about those. Also, a large subset of the population is overweight and malnourished simultaneously. They need to both decrease calories and change to healthier foods. You set them up for success by making a variety of small habit changes over time.
You have to gradually build up your fast, like with anything. Like if you go to the gym, you don't go off with the most amount of weight, you'll most likely snap something.
I'm pretty strongly on Peter's side here, as I find the fasting research to be pretty unconvincing because of all the confounding variables. Kind of how we're finding out that IF has no real benefit over caloric restriction, I think we're going to find similar things with fasting research, that the difference in impact is due to other factors like, people willing to fast for extended periods of time are more likely to be thoughtful about their health in ways that are difficult to control for in a trial.
Lipid Lower Meds and Early Health screenings AKA not covered by insurance...
Unfortunately…
So helpful this is!
@flexihussain glad you liked it!
Hidden gem channel!!💎
Wow! Thank you! That’s super kind of you!
You make it sound like Peter Attia promotes a specific diet or food in the book outlive. For nutrition Peter Attia states that the studies on nutrition are confounded and don’t even show great changes in the hazard ratio. At end of the chapter he suggests that if he did not mention your special diet or food, it is better to get out and exercise.
this summary presented is bogus. get the book and read it, use it as a reference
book and watch Attia’s own podcasts, not this one.
Amazing content ❤
So happy you like it! Thank you for the friendly comment!
Outstanding synopsis of Peter Attia’s book “Outlive”! Your technique is most appealing ! Your take on analyzing what bothers you about the book is most helpful!
Grateful to you!
Looking forward to more reviews! Have you done “Life Span”?
@tallybrillembourg6211 Thank you for the positive comment! So happy you liked it!
Lifespan animated book summary here: ruclips.net/video/3GSN9IbTK3I/видео.html
Thanks for this summary! I agree with his not mentioning the Blue Zones. I also think that his exercise recommendations are a bit extreme, ie, >37 hours total in a week!
The difference between Peter and others about protein can be because Peter, I feel, gives importance to the healthspan and this includes having a sound body. As he says being "a kickass 90 year old" and being able to play and throw your grandchildren. Now you don't necessarily have a broken body if you don't, but odds increase by far. I also agree it's not worth the risk and having higher life quality is sometimes more important than living longer.
Edit: He discusses the tradeoff here as far as I can remember ruclips.net/video/BqmG2y4IeY8/видео.html
the argument would be, being a frail 90 yo with the prospect of receiving newly discovered therapy vs being already dead but "happily" dead
@kuzdogan
Play with and 'throw' your grand children 🤣
(Sorry...just struck me funny)😁
9:25 Importance of good sleep
11:20 Preventing cancer
14:00 Fasting and Immunotherapy
16:55 Glucose monitoring
18:00 Stability
21:00 Metformin
21:30 Fasting-Protein is the most important macronutrient
22:40 Animal protein can be problematic
Well this was a joy...
Glad you liked it!
Allright, i may wanna watch this one day
i watch all ur video bro u need to upload more, love ur video i hope u came back!
You should further check the types of proteins David and Steve talk about. Animal protein is not something those authors promote. In fact, you can go with proteins from legumes, fruits, and vegetables while minimizing the amount of animal proteins, and still consume optimal levels of protein.
There are articles that kind of debunk the Blue zone studies.
Interesting! I’d love to know more about that. Do you remember what they say?
@@lovesense7246 Here is just one opinion.
runway.airforce.gov.au/resources/link-article/dr-saul-newman-debunking-blue-zone-longevity-myth#:~:text=A%20study%20by%20Dr%20Saul,have%20claimed%20higher%20longevity%20rates.
@@lovesense7246 I just went to your page, love the fact you are researching many different opinions. When you go down the rabbit hole of nutrition, health and wellness there is a whole plethora of different opinions. But for me it is ( n=1 ) We are all an experiment of 1. what works for me may not work for you and vice versa. To your health! Cheers
@@waynela3485 I'll check it out! Thank you!
2:45 how on earth can someone consume A LITER (1/4 gallon) of oil in a week????
Lotta popcorn
Thx a lot , what about David Sinclar book - so one for that also pls
@zibtihaj3213 You're welcome!
Lifespan by David Sinclair here: ruclips.net/video/3GSN9IbTK3I/видео.html
Great summary. Haven’t read the book but I’m very familiar with Peter Attia’s perspectives. Interesting that he left off the blue zones and find the fasting/blue zone/mtor/rapamycin stuff conflicting. I tend to think some mild fasting AND a little more protein is probably the best combo as one ages.
Protein in higher amounts only if muscles are in need from vigorous resistance training, otherwise excess protein is converted to glucose in anycase.
I do daily intermittent fasting
Stop eating by 5 pm and have breakfast at 8am
Has helped maintain my weight
Thats great be glad you're also a healthy human being@@karenkaren3189
It is unfortunate he doesn't talk about the Blue Zones as they have the key to Longevity and there is an evidenced based book which found that the drinking water in these areas is rich in Silica. Silica is essential for life and protects us from a neurotoxin aluminum which we are exposed to daily. The book is Silica Water the Secret to Healthy Longevity in the Aluminum Age by Dennis N Crouse. Here is a link to write up at his blog about a 6th blue zone he researched after seeing an exhibit at the Boston Museum of Science. He has a website, you tube channel, blog on blogger. Dennis is a chemist and has developed a recipe for making your own silica water, Silicade. He has anecdotal information about improvements people have seen from drinking silica rich water. prevent-alzheimers-autism-stroke.blogspot.com/2019/07/sixth-blue-zone-west-hechi-china.html
@fizywig nope - actually strength training, especially, opens the mTOR pathway, for muscle protein synthesis, in and of itself.
Also, gluconeogenesis occurs in the liver pretty much on a constant basis. The idea that 'too much' or 'high protein' promotes increased gluconeogenesis, is untrue.
I think Peter Attia is right about proteín. I am not sure thouth. I do know I feel a lot better when I eat more proteína and exercise more.
As I mentioned, most of the other health experts I listen to don’t think so, but maybe!
I have the book now, from the library, after a long wait. You got more out of it than I did - I'll try harder! I especially appreciated the sections on exercise and stability. I also was confused by the section on fasting, intermittent fasting. I have also learned to trust Roger Seheult at Medcram during the last 3 years.
Great stuff! Any plans to do this for more books?
That's the plan!
Regarding Keto: Is not what Peter recommends. He has said and written, that Keto is not sustainable. He does recommend to have a good quality source of protein.
You need to get those facts right.
Keto is sustainable. Where's the science that says it's not?
@@peterfrancisharrishe said in a podcast episode that it was not sustainable for him. He ate Keto for three years but said he could not do it again for a significant amount of time.
❤ thanks
You’re welcome!
Saturated fat may cause apoB counts to rise which is a risk factor for coronary artery disease. Can you please double check your information since you reported it was the rise in triglycerides that is bad for the heart. apoB particle count is more relevant to cardiovascular disease risk than serum triglycerides, generally speaking.
I'll reread that section of the book! I remember it saying it elevates triglycerides, but I might have made a mistake!
@@lovesense7246 no worries. I admire your production and creating this anyway. Wishing you success.
People like Dr Shawn Baker say that the Triglycerides/HDL ratio is the most important, and that it should be less than 2. If that is so it means that even if your LDL levels are high, the it would possibly be the Large Buoyant type LDL, which is not detrimental to cholesterol oxidation which is the chief cause of arterial plaquing.
While I do admire and respect Dr Attia, his sudden U turns on fasting, and Keto diets, makes me suspicious of the sudden hullabaloo on APO B
@@Itsme-e5j Which is why I find the APO B discussion to be very misleading...
@@pardogg "My first step in controlling my own cardiovascular risk was to begin to change my own diet, so as to lower my triglycerides (a contributor to apoB when they are high, as mine were), but more importantly to manage my insulin levels. I needed to get my metabolic house in order. I should note that my own solution at the time, a ketogenic diet, might not work for everyone, nor is it a diet to which I continue to adhere. In my clinical experience, about a third to half of people who consume high amounts of saturated fats (which sometimes goes hand in hand with a ketogenic diet) will experience a dramatic increase in apoB particles, which we obviously don't want. There are at least two reasons for this. First, it seems saturated fat contributes directly to the synthesis of excess cholesterol. Second, and more importantly, excess saturated fat causes the liver to reduce expression of LDL receptors, thereby reducing the amount of LDL removed from circulation."
Peter Attia, Outlive (pg. 133)
You were right! My memory failed me at the time of writing the script... sorry about that!
There is no study demonstrating that animal protein in isolation is linked to shorter lifespan. It is silly to come to the conclusion that "This person ate more meat and had cardiovascular issues therefore meat is the problem". The majority of the meat consumed in industrialized countries is factory farmed and loaded with saturated fat and preservatives.
Attia is spot on with this topic. Add clean protein and exercise to utilize it properly. Do not avoid animal protein due to an incorrect fear it is dangerous, just be selective with the sources.
bruh i am not even allowed to control my food at home how do i do keto
He fasts himself, he said it on Joe Rogan so I dont understand why he doesn't recommend it in his book
thanx!!! + really GREAT 👍🏻 that you keep being sceptical/critical!…. (cos me too i think fasting helps a lot cod of autophsgy and too much protein = silly)
Thanks! Yeah... that sounds strange to me, but we'll see what future studies find!
man the first couple of mins of this video is not my key takeaways from the book at all. sure he talks about keto but that's in relation to one of the "four horsemen" (metabolic dysfunction,) and also on how that type of diet may be useful when combating neurogenerative disease. also, the bit on flossing and sauna are correlated but not causal. (eg like the bacteria found in the mouth related to gum disease has also been found in folks with dementia in larger numbers than those without gum disease, but in the book he admits the relation is still unclear)
Is everyone not seeing the forest for the trees?
Alzheimers AND foul teeth are caused.... BY CARBS. It's is completely obvious that people with rotten teeth also have Alzheimers, because both have the same root cause.
You should have time stamped this
Done!
Thanks for the summary. On the ending, that whole topic I think is legitimately up for debate and is not settled, that's why it's confusing.
One side will say that we have rat studies where high protein levels are bad, the other will say in that same study a combination with high protein was longest lived. One side will say blue zones, the other side will say most blue zones likely exist due to welfare fraud rather than actually longer lifespan. One side will say human correlational studies show high protein is bad, the other side says those are just correlations and are likely picking up confounds, etc etc.
Fwiw how I'm practically thinking about it: all else equal less calories is obviously good, fasting per se is probably good for cancer treatment and maybe cancer prevention, the biggest downside is muscle loss which is important so if you are at risk of sarcopenia or could just use more muscle I would focus on that over fasting
excellent video, I found it really interesting. Though I will say that oftentimes I wonder if correlation and cause were confused. For example, how do you get a lot of grip strength? By working out, by actively building something with your hands etc. Maybe its just that people who do this, will not get neurodegenerative diseases. Because I doubt that artificially training grip strength with a specialized machine will make your brain function much better.
First of all, Attias Book is very good and your summary is pretty much on point. Besides that, Steven Gundry is a con. Don't even consider whatever he says. Sinclair is not a con, he is probably a good researcher on his field, but nutrition is NOT his field. His point of view on animal protein is garbage because he is basing this almost entirely on animal studies that simply cannot refer to humans. Mices are omnivores with a very clear and big focus on plant based foods. Humans evolved on meat and became the biggest and by far most skilled hunters on the planet. And humans don't live in a lab with full time care and in a germ- and stress-free environment. There a no mechanistic human studies that show animal protein could be harmful for us. The only human studies he refers to are epidemiological and basically show nothing. However, there are tons of studies that show plant based diets can harm us. Sinclair also said, that "when you eat is far more important than what you eat" - and that's probably the dumbest and worst nutritional advice I've ever heard of.
@12:37 per David Sinclair, it's actually not the AMOUNT of food they ate or that you eat, but the longevity is from eating at one time each day, which means you're not eating for all the rest of the day. actually the longevity effect occurs due to genes turned on after about 8-12 hours of not eating, genes which cause cellular autophagy; a general repairing and clean up mechanism. in theory, you can actually eat 3 meals in 1 if you do it all in 1 hour's timeframe per day and get the same effect, so technically to say "if you eat less" is incorrect
You forgot to mention the top gerontologist in US who has done most of the research on fasting and fmd creator Valter Longo PhD as well as Mark Mattson who ignite the " Intermittent Fasting" thing and did a lot of research on fasting and brain at John Hopkins Medical school, they advise against high protein diet ... you can read more about Valter Longo in his book " The longevity Diet"
Love the video and the animations
Could dial down the music, you've got a nice voice and the music makes it harder to understand
I think what’s confusing about peters fasting recommendation is that he fasts himself. He should signal what he actually does to ensure he meets his nutrients
I agree!
@21972012145525
No, he does not fast - to atophagy - any longer.
He assessed, at some recent point, over a year's time that his periodic fasting sessions (1x/quarter,I believe) promoted an increase in muscle loss, despite his doing everything correctly with his diet and strength training to promote, or at least maintain his muscle mass.
As a result, he no longer fasts. He's changed his educated opinion on fasting, as he has, as well, on some other supposedly beneficial health practices - such as taking Metformin prophylactically - which he was taking for perceived health benefits, as per some - or an initial study.
But with recent study findings on prophylactic use (or off-label usage) of Met. where those initial findings have been reversed, or at least negated, Dr. Attia hss reversed his opinion of taking Metformin prophylactically and no longer takes it.
That's what I respect and admire about Dr. Attia - and why I follow him, trust his educated opinion(s).
He us not one to doggedly stick with his initial findings (educated opinion) on health practices , etc.
As emerging study findings change, so does his opinion on the subject.
Not at all afraid to reverse himself about anything he previously may have endorsed at one time.
. Best way to be assured, in my pov, that the man makes a concerted effort against entertaining a bias that may turn out to be incorrect.
Love ❤️ that about him!
Can you make a video like this but on testosterone?
I’ll definitely consider it. Last week, my dad was telling me about a book called the testosterone advantage that changed his life many years ago, and that that should be the book I review next.
The Blue Zones thing is a bluff. Sardinia is one of them and it is qlso a European region. According to official statistics from Eurostat (the UE statistics agency) it don't even make the top ten among the European Regions in life expectancy indicators
I believe a Mediterranean diet is powerful.
Peter attia criticised that grip improving tool is useless...grip is improved by lifting weights, 💪...other excercises ...
Well doNe
Thank you!
Fasting!
Very interesting book! If this left you wanting more, we’ve got a chapter by chapter recap of the entire book on our page! 📚
Thanks for the summary, it sounds like I can skip this one. As you point out Peter has a number of rather odd views on things, which the more credible sources go against. I would recommend How Not To Die, for fact based nutrition, which is really the core of it.
Sorry, How Not To Die author, Dr, Gregor is a shill for the Peta crowd, a major source of his income. Hence, all the plant-based "science" which is highly cherry-picked and very low credibility.