Nature is lazy. That's both its greatest weakness and its greatest strength. God: *makes unimaginably big, complex Universe* Also God: *makes Universe a mostly empty void with like 5% of it made of actual stuff and like 90% of the stuff is hydrogen, AKA a single proton because 'Fuck it, that's good enough to make stars and shit.'* It's not a bug - it's a feature!
I feel like I dont understand anything, yet i feel like I understand everything at the same time. I feel so confused and its amazing. Chem is just magic I swear
I undertook high school chemistry so many of the terms used like “reagents” and “reduced” I understand what these mean, but I possess none of the skill in being able to apply it. Think of him as a handyman looking at a problem and deciding what tools to use. It’s a very similar thing except he’s thinking of which reagents and equipment he might use to get the result that he wants. This is some serious skill on display here.
Literally. The only things I know are the separator funnel, distillation and some elements. Why are they being used? What is their purpose? I have no idea
@@justanautisticnerd8969 Thats a sign you can understand because that means the knowledge is GRASPABLE, NOW GRWASP IT Before I started to do anything cool I felt the same way and just felt passionate
@@Hannah_The_Heretic it's probably because the shorts are easier to make. His videos tend to take a really long time; as he said for this hot sauce experiment, this one took months
It took me sooo long to realise this vid was over an hour long, I painted my gel nails, cooked and ate my dinner all to the soundtrack of Nile doing chemistry magic. Very nice, 10/10 would recommend.
didn't realize it was an hour long until i was halfway through because i was sewing but then by the half hour mark i got so invested that i made it fullscreen and started watching more intently
dang now i have a huge respect for hot sause companies, they must buy millions of gloves a year to make hot sauce, then they have to follow this guys instructions for hours on end just to make a few bottles, mad respect to them
Ingredients 2 roast peppers 1/4 onion 1 garlic clove 1 teaspoon of salt 1 gram of nordihydrocapsaicin If your having trouble with that last ingredient here is a simple guide
if there is anything i've learned from this man, it's that chemistry is a lot of haphazardly mixing things, then using fancy instruments to carefully seperate it into different things, over and over and over. it's great
for sure, i did one year of chemistry in college but i'm not that patient so lab days where such a dread that i just quit and studied mechanical engineering.
For centuries, alchemists had been trying to turn lead into gold. Little did they know, it wasn't lead that could be turned into gold, it was plastic gloves.
@@skussy69 I mean Alchemy was really just Very early misguided chemistry There are definitely possible things now that would get called alchemy in the old days It just happens turning things into gold Is really inefficient
Just a cautious FYI for anyone making their own hot sauce: I didn't see Nile add any vinegar at the end (although there was some in the peppers). Botulonium toxin grows in anerobic environments greater than 4.7pH, and is commonly detected when people improperly preserving things like chopped garlic in oil. I don't imagine this sauce would be particularly safe to consume after a couple of weeks unless refrigerated. Also, be sure to sterilise whatever bottle you use!
I don't think most viewers have the time, money, equipment or patience to use this video as a tutorial to make their own hot sauce. Still, this is good advice.
This content is what so many chemistry classes lack. A contextual goal. Not just molar weight and atomic information, but a context with which you can illustrate the relationships of chemicals, with visual examples of the molecular structure, and you can work backwards from there to the specific details! It makes soo much more sense this way, at least for me.
I don't think it's remotely possible to feature advanced organic chemistry like that without all the boring stuff you have to learn by heart. He took care of all the boring parts and left the fun ones for obvious reasons but you'd go crazy if he showed all the theoretic part.
@@Cookiedible This. Because there is no way you'd wholly enjoy Organic synthesis without understanding the mechanisms first. It's quite fun now that I've learned basic Orgo, I even jinxed it when he said he was gonna use the Permanganate as an oxidant
I think its just intro chem classes that feel impractical, because they are. Stoichiometry and equilibrium constants can be important I guess, but taking ochem feels much more practical. The knowledge of reactions is easily applied in a lab. Even if you never work in a organic chemistry lab, you see so many examples of what you're learning in student labs. Once you have enough reaction knowledge, its fun to know that you could make literally anything with several different synthetic pathways. I might be a little biased as an organic chemist, but these videos show the appeal of the subject. Nile is just an organic chemist who can do whatever sounds cool because he's a youtuber.
@@chancellorpalpatine7486 yeah but even organic chemistry has lots of very theoretical knowledge you need to learn in a vacuum. For example to reach a level where you understand why the right OH reacted from the starting molecule I think it's mandatory in any topic to have to go through boring theoretical stuff before you can hope to reach something you enjoy, and the further you specialize the more the pattern will reproduce
As a synthetic chemist, I have to say: the work done here is just so freaking elegant and methodologically sound, that I couldn't stop smiling every time he did the exact thing that I would have done, over and over again :) Have been following this channel for years, and will not stop anytime soon) P. S. I envy that you got to play around with one of those benchtop NMR machines, they look amazing on paper)
Yup, when pharmaceutical companies make new drugs they need someone to just go and make the molecules to test - and it is basically a job that's unsuitable for robots)
Every NileRed video sounds like something I would just skip to the end to see the results, but somehow watching chemistry at work in the hands of Nigel becomes VERY entertaining.
facts like i understand chemistry but it doesnt interest me really at this point in my life but after skipping 6 mins in i found myself an hour later writing this comment after not skipping another second.. i think it goes to show that the presentation of this video is just stellar
Simply due to lack of free time, I started in the middle. I was compelled to NOT skip forward at all. At some point I went back to the beginning so I could see how the gloves played into it. Then I went right to the point near the end where I had left off. I loved the entire thing. I have pronounced ADHD. Watching it in this manner didn’t bother me at all.
I will never again complain about moon logic recipes in video games when plastic gloves + vanilla = essence of spiciness is a real thing. nile, as ever, you're a man of focus, commitment, and sheer fucking will.
Or how the MineChem mod decided “hey, you know netherwart? Yeah, it’s actually cocaine hydrochloride.” (The HCl/hydrochloride (salts?) of drugs are to make them more soluble in the polar solvent of water, and thus also stomach acid.)
I just want to say that it's really impressive witnessing the lengths Nigel goes to for content. This video for example, has been in the making for 2 years?! That's quality, passion and commitment and I appreciate it as a viewer.
well he laid off the idea of making it for... what, a year and six months? assuming it took 4 months to put together. but yeah he's got passion for this
42:43 “it was a bunch of nice and white powder, and I was really hoping it was the right thing. The only way to confirm this though, was to run some tests on it.” *gets out credit card and straw*
@Doomgath - You win the RUclips comments award for this my friend. I rarely lol, but, like davie504, do so once in a great while. I looked at your comment again, so now 2x... Please provide your mailing address and bank account so I can send it as I am an exiled prince of a West African country living in a new country I created in the Maldives, so you can trust me. @Don't look at the last comment
"I'm sweating, I'm covered in sauce, my mouth hurts... and... I- I think this was exactly how it was supposed to end." is a line that makes me laugh more than some phrases that are even *intended* to be jokes
It’s hard to even fathom the amount of steps, time, and effort you had to put into this video. So much respect to you for making chemistry intriguing and entertaining for those of us who have never really had the chance to be exposed it.
what blows my mind even more, is this whole process took him weeks, and months of calculation, and yet plants have tiny machines inside their cells which make the molecule every day. Cells are amazing. They do the most insanely complicated things, without the organism even being aware of it. Imagine if you had to think your cells through the process of making an enzyme or digesting a food and putting it through the extremely chemically complex ATP pathway to create energy. With all our knowledge we don't have the intelligence to do that. How did it happen? It can't be mere chance.
@@SimonWoodburyForget I dunno, man, based on the molecular clock, we haven't had enough time for the successful mutation of all these biomolecules and systems. The rate of successful mutation is so prohibitively slow, that without some kind of agency directing it, it just wouldn't be possible to get where we are today in the time we have. It would require a universe that was orders of magnitude older than the science tells us it is. We throw the term 'millions of years' at the question as if it fixes everything, but when it's put under testable conditions, biochemistry is discovering currently just how implausible that is. We know the average rate of mutation based on studies on mutation in sperm cells in humans and primates and a bunch of other species. None of them produce beneficial mutations fast enough to cause this kind of machinery in the time we have. Most changes that will affect a biological system's function require a minimum of two convergent mutations in separate influential genes. And that's the minimum. Getting one mutation by chance isn't that hard, but getting two mutations in exactly the right genes to create the necessary change becomes exponentially more unlikely, just like guessing somebody's password gets exponentially more difficult the more characters in length it is. It does happen, but for example in mutations within bacteria it takes hundreds of millions of generations to produce a single change that involves two cooperating genes. When you extend that to multicellular organisms it becomes even harder, especially as those changes need to be made before the gametes of the animal have developed leaving an even smaller pocket of time. In human females for example that would require any mutation to take place while the infant was still in the womb, because after that the genetic data in the gametes are locked and any mutation in the original human will not be passed on. All this adds up to billions of years being nowhere near long enough. Heck, we think that humans evolved over just the most recent 6 million years. The new math of evolutionary biochemistry posits a really heavy question of how that could even be possible without something directing the changes? I'm not saying that we should expect to believe xyz or anything, I'm just saying we have a big conundrum right now that science has yet to fully comprehend or posit a reasonable answer for. We're only just learning about it now.
@@SimonWoodburyForget I'm not sure why you think I'm arguing for creationism... After all, creationism believes in even LESS time than we currently have in our models, and the entire issue is that we do not have _enough_ time. I am not sure you understood what I was getting at at all. The molecular clock is hardly a 'questionable idea about taxonomy' it's mainstream science. It's a well known and well understood metric. I honestly don't know why you would consider that questionable. Or are you referring to the fact that a human female's reproductive ova are genetically set before she's even out of the womb? That's biological fact as well. It's not 'questionable' it's in every biology textbook. Or the fact that most biological features are polygenic? That's basic science too. If you somehow have alternative information than what I stated, then go ahead and present it. You will find me highly receptive, so long as you don't stray into the realm of fiction and stick to the science. I also think it's ironic that you're making statements about finding reasons to believe in the supernatural to fill in whatever unknown there is, when you are doing the same thing you appear to be accusing me of, but using 'time' as your magic bullet. To fill in the gaps in your knowledge. It's just as much a cop out, because we don't know a way to make it solve the problems we have and whenever we look for solutions we find them ineffectual. I trained in Evolutionary Anthropology, that was my major. I know very well the complexities of the internal debate, and I was only talking about issues that are arising _within_ the scientific community. There is really no need to look any further than that. That is the only question that I was offering up for discussion. I specifically said that I was not offering any answers, nor any alternative 'belief' but that there is a problem that science has yet to answer. That is just factual. Try to deal with what people are saying rather than jumping to conclusions. Anyway, I'm not here to begin yet another debate, I was merely thinking aloud and expressing wonder. If that's too much for you to handle, maybe get off the internet for a while.
@@aserta without procedures, you’re spontaneous. Sometimes helps, sometimes doesn’t. Never makes u a nobody though, esp not this guy. He’s more successful than you could ever be. More than I could ever be as well, probably.
@The Confessor I think if he had said "Without procedures, you're nowhere.", it would have conveyed the message better. There is also the possibility he was being negative but benefit of the doubt.
@The Confessor Hey, don't dunk on min. wage workers. They're not lazy and are trying to support their family the best they can. Not everyone needs to be a doctor or a lawyer to not be a "failure". Real shitty of you. Dunk on those who purposely stay at home and do nothing. Then I would've found your comment more appealing, even though you don't get what @aserta meant.
33:45 while the reaction may have failed, I find this part very satisfying, the little particles being deposited tickled my brain in just the right way
I'm not a professional chemist, but I know that trying to make one chemical out of another just because they look sort of similar is something only a crazy person, or at least someone with way too much time on their hands, would do. Thank you, Nigel, for being the only mad scientist bold enough to do reactions like this and recording it for all of us to see.
But... that's how you make most chemicals both in lab and industrially. You look for a cheap, available precursor that looks chemically similar to the target molecule, then change a few functional groups and voila.
This video proves that chemistry is amazing, and why it's one of my favorite school subjects. You can theoretically turnny ordinary items into something like hpt sauce or grape soda!
I love the way he talks. At any point you have no idea if the sentence is gonna lead into ‘it didnt work at all” or “it worked flawlessly.” Idk how you manage to make chemistry tense.
@@Kooczsiit doesn’t at all. It’s the reason these videos are so captivating. He’s doing a damn good job to keep people watching hour long chemistry videos.
@@dan110024 its my personal opinion the reason i cant watch his videos for too long is because my mind starts to predict which tone of voice hes gonna use next, which in turn makes it annoying/boring for me
Im a Chemist doing my PhD in germany ans i absolutely love what you are doing, its like what chemistry should Look like. A perfect mixture of school chemistry for beginners and actual Research.
Its strayed too much out of practical stuff and too much into theory i'd say , seeing many exams becoming routine without any substatial critical thinkin behind them here in Iran , do you suffer from the same stuff over there too ?
@@akiamini4006 Imagine watching a guy turn gloves and some vanilla into a hot sauce and then complaining that "there's too much theory". So go replicate it. Put it on video.
@@WNActivist88 bruh aint no way ! Are you taking weed from your ass ?! I said in academical levels we deal with too much theories and seeing content like this is a nice change of pace ,
Nilered: refers to chemicals as their proper chemical names and/or common names, for instance, "Isononanoic acid" and "Jones Reagent" Also Nilered: Spicy molecule.
Served at NileRed's party: * chicken wings with plastic gloves hot sauce * toilet paper moonshine * grape soda also made from plastic gloves * diamonds infused soda water * cotton candy made from cotton balls * french fries fried in soap oil
I mean...... could be worse lol I like all of those things 🤷♂️ not sure I'd want to know I was drinking shitpaper shine until after the first couple glugs though lol
He got new NMR machine, but at the end of the video he says he wanted to "take a break from doing so much O-chem". I hope his next projects still involve mystery organic compounds, so his NMR is not wasted lol
2 года назад+47
It already saved this project. Without it he would likely just have assumed that things went wrong again.
This has been a wonderful hour spent relaxing to the multitude of distillations and interesting chemistry. I honestly kept watching and thinking to myself. Is it safe to taste it now? All through out the video.
The video presentations of glassware and operations are so beautiful I can't help thinking of them as some sort of conceptual works of art. Eg. 2:05 2:12 4:00 4:24 5:22 6:07 20:04 etc.
There will a point of time in the future where NileRed will post a whole 2+ hour Docu-series of just pure Chemistry and I'm ready to binge watch it no matter what.
bro, for real. I dont know anything about chemistry or half the things he is saying. But god help me if I dont sit through an hour of this just to see how indeed you can turn a glove in to hot sauce. i mean, come on.
As a commercial hot sauce manufacturer and fan of your channel, I’d say well done. Fascinating process for sure. Happy to send you some samples of our sauces and our capsaicin extraction from the spiciest peppers in the world. No gloves in our products however.
@@TheKoekiemonster1234 I could be wrong, but it sounds like they just wanted to send him some free stuff. If they said they wanted him to mention the product on camera, that would be different.
"I transferred it to a smaller beaker....then when all the methanol has evaporated, I transferred it to an even smaller one." The most normal sentence in this channel 😂😂
59:44 this is nilered’s Oppenheimer moment. He realised it was possible to make spice artificially, but it was only when he finally tasted it that he realised what hell he had unleashed upon his palette
I was peacefully listening to this video while doing other things. I had just sat down at my computer to keep watching it when I accidentally hit 0 on my numpad and the video started over again. That's when I realized it was an hour long and I am never gonna find where I left off at. Thank you Nigel excellent content as always.
I really love how Nigel changed through the years. He went from being quite shy and monotone to acting like someone you would love to be friends with, an absolute madlad of an entertainer
Man ate hot sauce he made with 1 of the 2 main ingredients was pure spice, which he made from gloves and vanilla. He then talked through the pain and explained what it felt like. God speed, Nile.
@@lucasmather4837Once you start adding contaminants, it will never be as spicy. Pure is on an entirely different level from anything you can buy commercially. It's so spicy that it can literally make it into your urine stream.
I've been wondering where you've been... now I see. You've been distilling and putting the results into various separatory funnels! Thanks for all you do, mate. This is a masterpiece.
“I’m usually bad at cooking, but I thought that this is so incredibly simple it can’t possibly be bad.” - NileRed, a Chemist, who works with mixing potentially dangerous chemicals in very specific sensitive amounts for a living.
aye, but how often do you hear him say "there was a bunch of unwanted junk floating around, and I'm not really sure what it is but I think its from impurities" and how often do you want your cook to be saying the same thing
Deeply hilarious to me that the guy who can basically manipulate the building blocks of matter using obscure instructions that would go over most people’s heads- says that he can’t cook 😂
If you convert the acid to methyl ester first, the amine group will easily form amide with a very small amount of NaOH catalysis. Additionally, only methyl alcohol is released as a byproduct.
As someone who studies chemistry, massive hats off to NileRed for doing this and pulling through. Organic chemistry can be a nightmare but he made it! Congratulations!!
RUclips supports Dangerous Stuff, even Hatepreachers. Greg Locke is still online, after all. But We CAN do somehting about it. If you dont wanna be not-updated, then try the newest video of 'Belief It Or Not' and the 2 GOP-Videos of 'Some More News'. They are really, really informtive. Not directly Science-related at all, i guess, but the 'Spirit' of Science (for the lack of a better word) is right-here. This is It.
At first, he was unsure whether to taste it. Then, he just casually shoots in methanol and then eats the sauce. That's what I call character development
i just sat here for an hour and six minutes and watched a man make hot sauce from gloves and vanilla and not once did I get bored, keep up the good work nile.
and by "with gloves" we mean by turning gloves into hot sauce like some sort of alchemist, not as in he was wearing them while making the sauce (though he was wearing some, safety first)
This is very similar to the experiment I saw in high school. It is the closest I have found. The one I saw collected the gasses separately and tested with flame and glowing splint. Then the experiment was performed again to rejoin the gasses with electricity. The only dissapointment I had was that the pipette tip was put under water, so it isn't clear that water did not get forced back up from the petri dish.
I now have the utmost respect for firms who produce spicy sauce since they must purchase millions of gloves each year and spend hours following this guy's directions simply to produce a few bottles.
Actually a very common misconception, big companies don’t actually use plastic gloves. That was just for this experiment. They are too expensive, instead they use plastic cups to make the spice.
What's absolutely hilarious to me is the actual amount of switching stuff from one container to another and stirring that chemistry actually is. We had it right as kids
These are so packed with juicy information they aren't even skimmable. As soon as I find myself in front of a NileRed video I'm like well, looks like I'll be spending another hour on RUclips.
@@familyguy1996iscool Know Sci Man Dan, Sci Show, Tier Zoo, Bluejay, Prophet of Zod and Hbomberguy? Those are some of my favorite 'smart' channel so i thought i share.
Nile Red 5 years from now; "I was looking at a lizard, and it occurred to me that since most creatures are just mostly made of water and carbon, I could design my own sentient species"
"It has been stated that, broken down to its barest components, the average adult human body is comprised of Water (35 L), Carbon (20 kg), Ammonia (4 L), Lime (1.5 kg), Phosphorous (800 g), Salt (250 g), saltpeter (100 g), Sulfur (80 g), Fluorine (7.5 g), Iron (5 g), Silicon (3 g) and fifteen traces of other elements." -FMA wiki
Chemisty is just pure magic to me... Just wizards Every time i hear him talk about bubbling it through something for insane amounts of time, i just have to think "who found this out?" Like you sat down and went "yeah, let's bubble this through [thing] for 12 hours" and your chemist mate next to you goes "don't do that with [other thing], i waisted 12 hours of my life testing that last week" Or how did they find out?!
And how do they find out which chemical they got for the first time? Like, Nile puts it into a machine that gives out a reading... but how did the reference reading was created in the first place?
interestingly, I have noticed a similarity with the vanillin being added. Some time ago I read about how certain spiders use venom containing vanillotoxins to activate the same receptors as we have for spicy pepper. I remember thinking at the time, "that's a strange name for a spicy neurotoxin..." but now it all makes sense!
You know you're doing something right when you make a video like this and a person like me (who was a C-student in Chemistry 25 years ago) can follow along without feeling like an idiot.
He should synthesize this again specifically for the last dab. If he made a large enough batch, I think Sean might be willing to sell a few of the bottles as limited releases, so Nigel could get some extra funding outside of Patreon!
I think it's worth noting that First We Feast has less than three times as many subscribers as NileRed. I think NileRed deserves huge credit for building up such a huge following without having big name guests like Gordon Ramsey and Salma Hayek. People come here for the chemistry, but stay for the Nigel.
@@acartwright10 well, did you hear what he said in the video? this was an extremely long and arduous process that took him several months (and years to actually get to it) just for enough of the chemical for 2 bottles of hot sauce. i don't he can just "whip up some more"
To be honest, I have studied a lot of these reduction, hydrogenation and all these crazy organic reactions with amines, carbonyls and alcohols, and while writing the reactions in paper, it felt really easy but looking at what you had to do, it is really tough man. Maintaining the temperature to purifying it wow, you are amazing. Congratulations on this project.
These videos always manage to fit somewhere between pure comedy, wizardry, and extremely educational and I love it. Thanks for the laughs and knowledge Nigel!
Things you normally don't hear Nile say: "this was pretty much the amount I expected" "occasionally just catch fire which we don't want". Grats on finally getting that reaction right
Tbf, that's tend to come up alot, especially in older vid (usually it's something abt the yelding is bad due to wasteful step). The wilding out tend to be on short ot nileblue. NileRed with his long and detail oriented videos is alway a respectable chemist/scientist imo.
@@asdasd1111ish just good-natured ribbing. I'm used to NileRed shorts by now, where he literally made a fireball and played with it. I am genuinely happy and proud that this went well for him compared to old videos, shows he's improving. And I love that we got another longer video even if I can barely understand it with my smol brain
What's even better is that the store probably started stocking up on it thinking "man, I'm not sure why people are buying so many of these but we need to make sure we have them in stock" only for them to just start piling up when he finished his video.
@@dukeofthedance8062 I can just see the stocking manager getting fired over this then coming across those two videos years later and being like "holy shit, this man cost me my job" then he goes back to his boss and shows him and he's just like "yea, sure, you probably had your friend make these"
It's super easy to make vanilla sugar for baking though. Just get some regular granulated sugar and some vanilla beans. Open the vanilla beans (use the insides for something else if you want, they don't have to go into the sugar, you can still get the flavor from the empty husk!) and put the beans in with the sugar. Shake periodically. It just takes time for the vanilla to infuse with the sugar.
Thats why only clowns believe in big bang and nothing creating everything and that you came from fish ... come on man anything is more belivable then that xD
@@slavplaysgames not really, and it’s called “The Big Bang Theory” for a reason man, it’s just a theory that hasn’t been 100% proven, but it has the most evidence, and I could say that everyone that believes in gods creating things because they were bored are clowns because anything is more believable then that.
@@tjailinht9412 Yeah I respect people who believes in creationism but those who call others clowns for believing a more believable theory are the true clowns.
I love how chemistry is a nice mix of "this has to be exactly perfect or it won't work" and "just eyeball it dude it'll be fine"
"trust me bro this will work"
That concept can be applied to psychedelics too!
You are so right!
@@sophiacristina and alcohol
Nature is lazy. That's both its greatest weakness and its greatest strength.
God: *makes unimaginably big, complex Universe*
Also God: *makes Universe a mostly empty void with like 5% of it made of actual stuff and like 90% of the stuff is hydrogen, AKA a single proton because 'Fuck it, that's good enough to make stars and shit.'*
It's not a bug - it's a feature!
I find it fascinating that I can watch an 1 hour video without understanding anything and not be bored
I feel like I dont understand anything, yet i feel like I understand everything at the same time.
I feel so confused and its amazing.
Chem is just magic I swear
I undertook high school chemistry so many of the terms used like “reagents” and “reduced” I understand what these mean, but I possess none of the skill in being able to apply it. Think of him as a handyman looking at a problem and deciding what tools to use. It’s a very similar thing except he’s thinking of which reagents and equipment he might use to get the result that he wants. This is some serious skill on display here.
Literally. The only things I know are the separator funnel, distillation and some elements. Why are they being used? What is their purpose? I have no idea
ME TOO
@@justanautisticnerd8969 Thats a sign you can understand because that means the knowledge is GRASPABLE, NOW GRWASP IT
Before I started to do anything cool I felt the same way and just felt passionate
My favorite thing an this channel is that every episode feels like it’s going to be clickbait but he delivers *every. single. time.*
And he makes it enthralling somehow
"Gloves into hot sauce? HAH. Yeah right. That's not even possible idio-"
i think my favorite part of watching him is just *spinny pill go brrrrrrr*
I'm just glad he's posting videos and not just stupid shorts, I genuinely thought this channel was dead.
@@Hannah_The_Heretic it's probably because the shorts are easier to make. His videos tend to take a really long time; as he said for this hot sauce experiment, this one took months
24:17 “I wasn’t exactly sure how many to get, but I figured 18 was a descent amount.” Classic Nile
It took me sooo long to realise this vid was over an hour long, I painted my gel nails, cooked and ate my dinner all to the soundtrack of Nile doing chemistry magic. Very nice, 10/10 would recommend.
Nile red is great background noise for daily life^ even tho I've seen all his videos atleast 10 times each I just like hearing him explain things
didn't realize it was an hour long until i was halfway through because i was sewing but then by the half hour mark i got so invested that i made it fullscreen and started watching more intently
I thought this was 10 minutes lol
I cooked my nails and painted my dinner
@@Kwisatz_HaderachXIII I too do that
dang now i have a huge respect for hot sause companies, they must buy millions of gloves a year to make hot sauce, then they have to follow this guys instructions for hours on end just to make a few bottles, mad respect to them
absolutely crazy, cant even imagine how many gloves it would take to make the world's spiciest sauce 😞
@@shrekfrog no wonder 1 chip challenge costs so much for one chip, imagine how many gloves 🤯🤯🤯
if they followed his instructions, hot sauce wouldn’t exist before this video
@@oscarthagrouch You're right, it didn't
@@oscarthagrouch r/wooooosh
Ingredients
2 roast peppers
1/4 onion
1 garlic clove
1 teaspoon of salt
1 gram of nordihydrocapsaicin
If your having trouble with that last ingredient here is a simple guide
Instructions unclear.
I made pure uranium-238.
@@garlicxihow much for 100 grams?
instructions unclear some how it became hydrochloric acid
Instructions unclear. Blew up the neighbors house
You forgot the 3 page preface about the history of your great grandma's farm and how she loved glove sauce.
"...for what felt like the billionth distillation..." meanwhile I'm expecting him to put it all into a separatory funnel again.
Well yea but those ones are my favorite :)
Well.. separating and washing can be tedious but it is relatively fast. Multiple distillations on the other hand .. hours and hours and hours..
Imagine Nigel being interviewed at Hot Ones and bringing his own hot sauce from gloves and vanilla.
Replace Da Bomb with “NileRed’s Spicy Molecule”
Bro I said that too 😅
BROOO i wanna see that happen lmao
MAKE THIS HAPPEN!!!
nilered's red hot hot sauce sauce
if there is anything i've learned from this man, it's that chemistry is a lot of haphazardly mixing things, then using fancy instruments to carefully seperate it into different things, over and over and over. it's great
And chemical engineers spend their time learning and optimizing the mixing and the separating
only its not "haphazardly"
@@Waldo-Manfred NileBlue would like a word... ;)
Biochemistry is the same, but smaller
That's pretty much correct (I'm a professional synthetic chemist)
NileRed was so enthralled by the question of whether he _could,_ he never stopped to think if he _should..._
That's the difference between the common man and a RUclipsr : for the latter the second question isn't even a question.
I just rewatched Jurassic Park today!
He has, its never stopped him
Nigel is probably making some kind of stinky spicy hot sauce concoction.
But any way
After just two videos, I am thoroughly convinced that chemists are the most patient people in the world.
for sure, i did one year of chemistry in college but i'm not that patient so lab days where such a dread that i just quit and studied mechanical engineering.
No doubt!
For centuries, alchemists had been trying to turn lead into gold. Little did they know, it wasn't lead that could be turned into gold, it was plastic gloves.
I was just thinking that this is probably as close to real life "alchemy" as you're gonna get
Make sure he didn't hide any Philosopher's Stone and human sacrifices backstage.
@@skussy69 I mean if you had a billion years with the particle accelerator
@@skussy69 I mean
Alchemy was really just
Very early misguided chemistry
There are definitely possible things now that would get called alchemy in the old days
It just happens turning things into gold
Is really inefficient
Well obviously. Man I can’t believe they couldn’t figure that out
Just a cautious FYI for anyone making their own hot sauce: I didn't see Nile add any vinegar at the end (although there was some in the peppers). Botulonium toxin grows in anerobic environments greater than 4.7pH, and is commonly detected when people improperly preserving things like chopped garlic in oil. I don't imagine this sauce would be particularly safe to consume after a couple of weeks unless refrigerated. Also, be sure to sterilise whatever bottle you use!
I don't think most viewers have the time, money, equipment or patience to use this video as a tutorial to make their own hot sauce.
Still, this is good advice.
@@ridinkulous I think this is just a tip for hot sauce production in general
@@quantum.codex42 sounds as for any fermenting.
@@vladimirpoutine4140 I love your username lmao
@@quantum.codex42 I read it "Vladimir Pootin"
This content is what so many chemistry classes lack.
A contextual goal. Not just molar weight and atomic information, but a context with which you can illustrate the relationships of chemicals, with visual examples of the molecular structure, and you can work backwards from there to the specific details!
It makes soo much more sense this way, at least for me.
I don't think it's remotely possible to feature advanced organic chemistry like that without all the boring stuff you have to learn by heart. He took care of all the boring parts and left the fun ones for obvious reasons but you'd go crazy if he showed all the theoretic part.
@@Cookiedible This. Because there is no way you'd wholly enjoy Organic synthesis without understanding the mechanisms first. It's quite fun now that I've learned basic Orgo, I even jinxed it when he said he was gonna use the Permanganate as an oxidant
I think its just intro chem classes that feel impractical, because they are. Stoichiometry and equilibrium constants can be important I guess, but taking ochem feels much more practical. The knowledge of reactions is easily applied in a lab. Even if you never work in a organic chemistry lab, you see so many examples of what you're learning in student labs. Once you have enough reaction knowledge, its fun to know that you could make literally anything with several different synthetic pathways. I might be a little biased as an organic chemist, but these videos show the appeal of the subject. Nile is just an organic chemist who can do whatever sounds cool because he's a youtuber.
@@chancellorpalpatine7486 yeah but even organic chemistry has lots of very theoretical knowledge you need to learn in a vacuum. For example to reach a level where you understand why the right OH reacted from the starting molecule
I think it's mandatory in any topic to have to go through boring theoretical stuff before you can hope to reach something you enjoy, and the further you specialize the more the pattern will reproduce
Excellent point. (And that general idea holds true for many other subjects as well!)
NileRed Patch Fixes:
-Added hexanes.
-Added hexanes
-Added hexanes.
As a synthetic chemist, I have to say: the work done here is just so freaking elegant and methodologically sound, that I couldn't stop smiling every time he did the exact thing that I would have done, over and over again :)
Have been following this channel for years, and will not stop anytime soon)
P. S. I envy that you got to play around with one of those benchtop NMR machines, they look amazing on paper)
wait, you're telling me there a job just for making stuff like this??
@@Coolcanny there's a job for almost anything.
do you have an RV in the middle of the New Mexico Desert?
Yup, when pharmaceutical companies make new drugs they need someone to just go and make the molecules to test - and it is basically a job that's unsuitable for robots)
I do love the chemistry in that show, it's delightfully accurate :)
hated chemistry in high school, yet have been waiting for this notification for months
A duck of culture I see
Same lol
Hmmm August and chemistry this seems dangerous
Quack
Didnt expect to see you here
Every NileRed video sounds like something I would just skip to the end to see the results, but somehow watching chemistry at work in the hands of Nigel becomes VERY entertaining.
facts like i understand chemistry but it doesnt interest me really at this point in my life but after skipping 6 mins in i found myself an hour later writing this comment after not skipping another second.. i think it goes to show that the presentation of this video is just stellar
@@tristanconn11 I just realized that I watched the entire video without skipping forward at all.
@@gregwessendorf same lol
It's cool, I skipped to the end for you.
Simply due to lack of free time, I started in the middle. I was compelled to NOT skip forward at all. At some point I went back to the beginning so I could see how the gloves played into it. Then I went right to the point near the end where I had left off.
I loved the entire thing.
I have pronounced ADHD. Watching it in this manner didn’t bother me at all.
The smartest thing NileRed has ever done is assume that his viewers have barely any understanding of what he’s talking about.
for all i know he could be greatly simplifying it and it I still won't understand lol
Chemistry majors have somewhat of an understanding
I saw nilered once in a restaurant bathroom. He wanted to play swords and I quickly scurried away 😯
@@scottpitner4298wtf bro
I will never again complain about moon logic recipes in video games when plastic gloves + vanilla = essence of spiciness is a real thing. nile, as ever, you're a man of focus, commitment, and sheer fucking will.
Any sufficiently advanced science is indistinguishable from magic.
Great technique. PhD chemist
Or how the MineChem mod decided “hey, you know netherwart? Yeah, it’s actually cocaine hydrochloride.”
(The HCl/hydrochloride (salts?) of drugs are to make them more soluble in the polar solvent of water, and thus also stomach acid.)
@@vigilantcosmicpenguin8721
Pretty much. Magic is just science you don't understand
He is an irl john wick
I love how Nile only talks in past tense hypothetical so you never know if an experiment worked until the very end.
I love that!
Makes it tense.
I mean look at the shit he does for a living.
He has transcended us
@@krotchlickmeugh627 y e s
thats how lab reports are traditionally written, which i always thought he did on purpose
That's how it worked for me when in college. No one ever knew.
I just want to say that it's really impressive witnessing the lengths Nigel goes to for content. This video for example, has been in the making for 2 years?! That's quality, passion and commitment and I appreciate it as a viewer.
well he laid off the idea of making it for... what, a year and six months? assuming it took 4 months to put together. but yeah he's got passion for this
Exactly!
42:43 “it was a bunch of nice and white powder, and I was really hoping it was the right thing. The only way to confirm this though, was to run some tests on it.” *gets out credit card and straw*
NilesRed: “I’m feeling kinda hungry”
*eyes box of PPE menacingly*
468 likes, but no replies
some comments have 0 likes, but they have replies.
@@shiloranxxer sh shhhhh let it be :)
*PPE* 😳
@@Sumtinggs a whole box
@Doomgath - You win the RUclips comments award for this my friend. I rarely lol, but, like davie504, do so once in a great while. I looked at your comment again, so now 2x...
Please provide your mailing address and bank account so I can send it as I am an exiled prince of a West African country living in a new country I created in the Maldives, so you can trust me. @Don't look at the last comment
I love how Nigel has fully embraced his inner alchemist at this point.
"I'm sweating, I'm covered in sauce, my mouth hurts... and... I- I think this was exactly how it was supposed to end."
is a line that makes me laugh more than some phrases that are even *intended* to be jokes
i mean... 19:05
@@kyrbdere So, how did your date go last night man?
NileRed: 19:05
bless these men
@@nloc1929 bruh
What about that pun at 1:05:31
My favorite thing about this channel is that, despite the fact that every episode seems like clickbait, he consistently delivers.
It’s hard to even fathom the amount of steps, time, and effort you had to put into this video. So much respect to you for making chemistry intriguing and entertaining for those of us who have never really had the chance to be exposed it.
what blows my mind even more, is this whole process took him weeks, and months of calculation, and yet plants have tiny machines inside their cells which make the molecule every day. Cells are amazing. They do the most insanely complicated things, without the organism even being aware of it. Imagine if you had to think your cells through the process of making an enzyme or digesting a food and putting it through the extremely chemically complex ATP pathway to create energy. With all our knowledge we don't have the intelligence to do that. How did it happen? It can't be mere chance.
@@SimonWoodburyForget I dunno, man, based on the molecular clock, we haven't had enough time for the successful mutation of all these biomolecules and systems. The rate of successful mutation is so prohibitively slow, that without some kind of agency directing it, it just wouldn't be possible to get where we are today in the time we have. It would require a universe that was orders of magnitude older than the science tells us it is. We throw the term 'millions of years' at the question as if it fixes everything, but when it's put under testable conditions, biochemistry is discovering currently just how implausible that is. We know the average rate of mutation based on studies on mutation in sperm cells in humans and primates and a bunch of other species. None of them produce beneficial mutations fast enough to cause this kind of machinery in the time we have.
Most changes that will affect a biological system's function require a minimum of two convergent mutations in separate influential genes. And that's the minimum. Getting one mutation by chance isn't that hard, but getting two mutations in exactly the right genes to create the necessary change becomes exponentially more unlikely, just like guessing somebody's password gets exponentially more difficult the more characters in length it is. It does happen, but for example in mutations within bacteria it takes hundreds of millions of generations to produce a single change that involves two cooperating genes. When you extend that to multicellular organisms it becomes even harder, especially as those changes need to be made before the gametes of the animal have developed leaving an even smaller pocket of time. In human females for example that would require any mutation to take place while the infant was still in the womb, because after that the genetic data in the gametes are locked and any mutation in the original human will not be passed on. All this adds up to billions of years being nowhere near long enough. Heck, we think that humans evolved over just the most recent 6 million years. The new math of evolutionary biochemistry posits a really heavy question of how that could even be possible without something directing the changes? I'm not saying that we should expect to believe xyz or anything, I'm just saying we have a big conundrum right now that science has yet to fully comprehend or posit a reasonable answer for. We're only just learning about it now.
@@SimonWoodburyForget I'm not sure why you think I'm arguing for creationism... After all, creationism believes in even LESS time than we currently have in our models, and the entire issue is that we do not have _enough_ time. I am not sure you understood what I was getting at at all. The molecular clock is hardly a 'questionable idea about taxonomy' it's mainstream science. It's a well known and well understood metric. I honestly don't know why you would consider that questionable. Or are you referring to the fact that a human female's reproductive ova are genetically set before she's even out of the womb? That's biological fact as well. It's not 'questionable' it's in every biology textbook. Or the fact that most biological features are polygenic? That's basic science too. If you somehow have alternative information than what I stated, then go ahead and present it. You will find me highly receptive, so long as you don't stray into the realm of fiction and stick to the science.
I also think it's ironic that you're making statements about finding reasons to believe in the supernatural to fill in whatever unknown there is, when you are doing the same thing you appear to be accusing me of, but using 'time' as your magic bullet. To fill in the gaps in your knowledge. It's just as much a cop out, because we don't know a way to make it solve the problems we have and whenever we look for solutions we find them ineffectual. I trained in Evolutionary Anthropology, that was my major. I know very well the complexities of the internal debate, and I was only talking about issues that are arising _within_ the scientific community. There is really no need to look any further than that. That is the only question that I was offering up for discussion. I specifically said that I was not offering any answers, nor any alternative 'belief' but that there is a problem that science has yet to answer. That is just factual. Try to deal with what people are saying rather than jumping to conclusions.
Anyway, I'm not here to begin yet another debate, I was merely thinking aloud and expressing wonder. If that's too much for you to handle, maybe get off the internet for a while.
Nilered needs to start a cooking channel and keep the format exactly the same
"Turning plastic gloves into a chicken sandwich." Lmao
NileStove
Nilegreen
@@yungccsonar nilegreen already exists
@@SaphiraThePhantom can we do nilepurple
I love how this guy doesn't know what he's doing but also knows exactly what he's doing
It's not that he doesn't know what he's doing. It's that he doesn't have the procedures. Without procedures, you're nothing.
@@aserta without procedures, you’re spontaneous. Sometimes helps, sometimes doesn’t. Never makes u a nobody though, esp not this guy. He’s more successful than you could ever be. More than I could ever be as well, probably.
@The Confessor I think if he had said "Without procedures, you're nowhere.", it would have conveyed the message better. There is also the possibility he was being negative but benefit of the doubt.
@Aloura @The Confessor you're both completely misinterpreting the intent of his statement.
@The Confessor Hey, don't dunk on min. wage workers. They're not lazy and are trying to support their family the best they can. Not everyone needs to be a doctor or a lawyer to not be a "failure". Real shitty of you. Dunk on those who purposely stay at home and do nothing. Then I would've found your comment more appealing, even though you don't get what @aserta meant.
33:45 while the reaction may have failed, I find this part very satisfying, the little particles being deposited tickled my brain in just the right way
This man spent 2 years trying to make a single bottle of hot sauce out of gloves and vanilla. His dedication is incredible.
i love how he can spend years on the spicy but then for the actual sauce he buys already grilled peppers in a jar LMAO
I'm checking comments again after 2 months and see this
@@julia4740 it’s grilled bell peppers.
@@aaronnguyen2795 i know i mean its fun how he has a lot of patient for chemistry but cooking he doesnt even want to start the oven hahaha
he's got experience. The artificial grape flavoring was just as intresting.
I'm not a professional chemist, but I know that trying to make one chemical out of another just because they look sort of similar is something only a crazy person, or at least someone with way too much time on their hands, would do. Thank you, Nigel, for being the only mad scientist bold enough to do reactions like this and recording it for all of us to see.
Essentially alchemy, but less safe
@@marcosdarcy2221 essentially alchemy but real
But... that's how you make most chemicals both in lab and industrially. You look for a cheap, available precursor that looks chemically similar to the target molecule, then change a few functional groups and voila.
Lab safety rules: "always use gloves when conducting experiments."
Nile: "Oh, ok."
these are safty rules NOT safety rules so do not try at any houze
@@shroovey huh
Hhahahahhaa
@@jacksonohno you spelled saftey wrong, i think that's the joke Torzay was making
You usually shouldn't eat stuff made in a lab, but in this case it was made from safy gloves, so its safe because it followed lab safy rules.
This video proves that chemistry is amazing, and why it's one of my favorite school subjects. You can theoretically turnny ordinary items into something like hpt sauce or grape soda!
I love the way he talks. At any point you have no idea if the sentence is gonna lead into ‘it didnt work at all” or “it worked flawlessly.” Idk how you manage to make chemistry tense.
I feel like it gets kinda annoying over time
@@Kooczsinope
@@soup_fetcher_boi 😭😭
@@Kooczsiit doesn’t at all. It’s the reason these videos are so captivating. He’s doing a damn good job to keep people watching hour long chemistry videos.
@@dan110024 its my personal opinion
the reason i cant watch his videos for too long is because my mind starts to predict which tone of voice hes gonna use next, which in turn makes it annoying/boring for me
Im a Chemist doing my PhD in germany ans i absolutely love what you are doing, its like what chemistry should Look like. A perfect mixture of school chemistry for beginners and actual Research.
Its strayed too much out of practical stuff and too much into theory i'd say , seeing many exams becoming routine without any substatial critical thinkin behind them here in Iran , do you suffer from the same stuff over there too ?
@@akiamini4006based on how the schnitzel said it, i would say its also too much theory.
@@akiamini4006 Imagine watching a guy turn gloves and some vanilla into a hot sauce and then complaining that "there's too much theory".
So go replicate it. Put it on video.
@@WNActivist88 bruh aint no way ! Are you taking weed from your ass ?! I said in academical levels we deal with too much theories and seeing content like this is a nice change of pace ,
@@WNActivist88 i think he meant chemistry in universities
Nilered: refers to chemicals as their proper chemical names and/or common names, for instance, "Isononanoic acid" and "Jones Reagent"
Also Nilered: Spicy molecule.
@@himarei you're hard to pronounce
"It's right on that threshhold.... of being completely inedible." LMFAO i love it
Served at NileRed's party:
* chicken wings with plastic gloves hot sauce
* toilet paper moonshine
* grape soda also made from plastic gloves
* diamonds infused soda water
* cotton candy made from cotton balls
* french fries fried in soap oil
I mean...... could be worse lol I like all of those things 🤷♂️ not sure I'd want to know I was drinking shitpaper shine until after the first couple glugs though lol
@@tyhumphreys9149 “shitpaper shine” 💀
Full moon shine
@@tyhumphreys9149 you know what, this entire comment section is rather hilarious, but your comment here might just take the cake for me 😂
@@therussianprincess7036 glad I could add something to your day 😂
Cashier: "What are you buying so much vanilla sugar for?"
Nilered: "Hot Sauce."
She Wasn't Gonna Question How Something So Sweet Was Gonna Become Spicy, And Good Thing Because She Would Barely *REACT* To The Explanation.
Hahaha
Im imagining heavy breathing and a decently long pause between those
Cashier: "Oh some sort of vanilla-flavored hot sauce? I've never heard-"
Nigel: "No."
I was liked for the 1000th like
Feel like having a NMR machine is going to be a game changer for this channel.
He got new NMR machine, but at the end of the video he says he wanted to "take a break from doing so much O-chem". I hope his next projects still involve mystery organic compounds, so his NMR is not wasted lol
It already saved this project. Without it he would likely just have assumed that things went wrong again.
The fact that NMR machines exist at that scale is honestly incredible
Doing TLC analysis once in a while would be an even cheaper game changer 😁
Next video he adds a full GC-MS to his setup
this man is single handedly changing chemistry books by creating new weird compound preparation methods😂😂,i 100% recommend
This has been a wonderful hour spent relaxing to the multitude of distillations and interesting chemistry. I honestly kept watching and thinking to myself. Is it safe to taste it now? All through out the video.
Didn’t realise it’s 1h long till seeing you mentioned it. 3 min in, I was like hmm progress bar looks a bit long?
It's extremely relaxing to me too. It's like smart person asmr.
Yeah, of have been licking my fingers all along. This is why I'd be a dead organic chemist.
The video presentations of glassware and operations are so beautiful I can't help thinking of them as some sort of conceptual works of art. Eg. 2:05 2:12 4:00 4:24 5:22 6:07 20:04 etc.
“Damn, this sauce tastes great! How’d you make it?”
Nile, sweating: a chef never reveals his recipe
he just revealed it to 12 million people tho
@@crylune r/woosh
The new “a magician never reveals his secret”.
Though I find chemistry to be pretty magical, so that’s not too far off.
@@madanmatcha7484 literally how, i got the joke. also r/ihavereddit
@@crylune Chill brother, it's just for fun.
There will a point of time in the future where NileRed will post a whole 2+ hour Docu-series of just pure Chemistry and I'm ready to binge watch it no matter what.
bro, for real. I dont know anything about chemistry or half the things he is saying. But god help me if I dont sit through an hour of this just to see how indeed you can turn a glove in to hot sauce. i mean, come on.
My guy here is a straight up modern full metal alchemist.
He's just an alchemist
As a commercial hot sauce manufacturer and fan of your channel, I’d say well done. Fascinating process for sure. Happy to send you some samples of our sauces and our capsaicin extraction from the spiciest peppers in the world. No gloves in our products however.
I think sponsorships cost money though
@@TheKoekiemonster1234 I could be wrong, but it sounds like they just wanted to send him some free stuff. If they said they wanted him to mention the product on camera, that would be different.
As a chili and hot sauce enjoyer, I appreciate
“It’s time for bedtime stories”
*Watches NileRed’s latest video*
no gloves? kinda a deal breaker there bukoo
"If you could bring one food with you on a desert island, what would it be?"
Nilered: "Plastic gloves"
Surviving on hot sausage is kinda scary, but grape soda doesn’t seem all that bad.
One small problem tho…..
D I A B E T E S
@@randaranatunga7259 do you mean sauce instead of sausage?
@@fxri nah
I laughed SO hard at this!
that's a ton of equipment to also take on an island 🤣
I always love how he mentions every single note and observation he has, it’s not just entertainment, it’s a professional experiment
Wait this was supposed to be experiment? It was entertainment 😂
@@M1551NGN0 lol yeah
@@playerjack2566 an educational entertaining experiment i would say
@@The_Jazziest_Coffee very entertaining 😂
That is the difference between just "fuck around and find out" and science.
"I transferred it to a smaller beaker....then when all the methanol has evaporated, I transferred it to an even smaller one."
The most normal sentence in this channel 😂😂
"Plastic Gloves + Vanilla = Hot Sauce" is something that perfectly describes NileRed's entire channel
Omw to add that to minecraft education edition
Hence: Hot Sauce - Vanilla = Plastic Gloves
Woah dude you forgot the hydrochloric acid!
@@cluxter-orghot sauce + vanilla = vsauce, Michael here
cant forget the drain cleaner
59:44 this is nilered’s Oppenheimer moment. He realised it was possible to make spice artificially, but it was only when he finally tasted it that he realised what hell he had unleashed upon his palette
“I have become death, destroyer of taste buds” - Nile
My like turned it to 666 likes. Awesome. Think it fits on a comment about this 😂
I have become sauce, bringer of hot
I mean eating the raw essence of spice probably isn’t very fun lol
if i had a nickel every time nilered made something edible out of gloves, i’d have 2 nickels, which is not a lot but it’s weird it happened twice
Lmao
Thrice! Thrice! Thrice!
I see the reference 👀
Doofenshmirz will sue you
his quote is copyrighted
Doofenshmirtz
schmirts? idfk
I was peacefully listening to this video while doing other things. I had just sat down at my computer to keep watching it when I accidentally hit 0 on my numpad and the video started over again. That's when I realized it was an hour long and I am never gonna find where I left off at. Thank you Nigel excellent content as always.
Now for the final part of the trilogy:
*“Turning grape soda into plastic gloves, then turning them into hot sauce”*
*into KFC
Speaking of hot sauce.... got me some hellfire "fear this" hot sauce I've already consumed half the bottle of since last weekend 🤣🤣
Im waiting 😏
@Don't read profile photo spammer
Nah just "turning grape soda into hot sauce"
I really love how Nigel changed through the years. He went from being quite shy and monotone to acting like someone you would love to be friends with, an absolute madlad of an entertainer
Who you would love to be friends with
@@ChlorinatedPond Every pyromancer and alchimists
@@ChlorinatedPond people who play around with dangerous things but still know what theyre doing and have it under control
@Erinn Saige Matas exactly
Man ate hot sauce he made with 1 of the 2 main ingredients was pure spice, which he made from gloves and vanilla. He then talked through the pain and explained what it felt like. God speed, Nile.
Also when he had the pure Nordihydrocapsaicin, it was 9.9 million scovile units. Which is nearly 5 times hotter than a Carolina Reaper
@@moneysing2026how much than pepper X (it’s made by the same guy who made the reaper and hasn’t been released to my knowledge)
About 6 million scovile units higher than Pepper X@@lucasmather4837
@@lucasmather4837 pepper x is estimated to be around 3.2 million scoville
@@lucasmather4837Once you start adding contaminants, it will never be as spicy. Pure is on an entirely different level from anything you can buy commercially. It's so spicy that it can literally make it into your urine stream.
19:03 PLEASE RETHINK YOUR WORDS
I've been wondering where you've been... now I see. You've been distilling and putting the results into various separatory funnels! Thanks for all you do, mate. This is a masterpiece.
You forgot to distill this comment and put it in a seperatory funnel
You can check his other channels, where he posts more frequently :)
“I’m usually bad at cooking, but I thought that this is so incredibly simple it can’t possibly be bad.”
- NileRed, a Chemist, who works with mixing potentially dangerous chemicals in very specific sensitive amounts for a living.
That he often ingests.
Cooking food is a different beast of chemistry, extremely subjective at that
That means he must be amazing at baking
aye, but how often do you hear him say "there was a bunch of unwanted junk floating around, and I'm not really sure what it is but I think its from impurities" and how often do you want your cook to be saying the same thing
@@Revoku ever tried a pressure cooker? XD
Nigel: Is supposedly bad at cooking
Also Nigel: Can make a full meal from plastic gloves, bars of soap, and toilet paper.
also a bunch of chemicals, but for the sake of the joke let's pretend I've never said it
And cotton balls for desert
This coment deserve a 1m likes... at least
so true
Don't worry. Everyone names Nigel is good at cooking
Deeply hilarious to me that the guy who can basically manipulate the building blocks of matter using obscure instructions that would go over most people’s heads- says that he can’t cook 😂
I love how he goes through 300 steps to make the spicy chemical, but can't be bothered to roast peppers.
Chemistry is easier than cooking I guess
😂😂😂 why is this true?
@@idontknowyet2875 Its a science thing. Its the wow factor. Or its our nerdness. You choose
thats the point of the video and I love it
That’s not science lol
"Do we have hot sauce?"
Nigel: **slowly holds up box of gloves**
and some bunch of vanilla sugar packets
and it took several weeks
don’t forget all the equipment 😂
한국인도 이걸 보는구나
@@leviseo9536 응 미쳤어 ㅋㅋㅋㅋ
this man is the only person who can keep me focused on something i can't even remotely understand for over an hour
So you're either mesmerized and hypnotized, or brain dead.
@@RosyOutlook2 no, he's just a nilered enjoyer
fr
@@aLOIxUhhcould be all four 🤔
real
If you convert the acid to methyl ester first, the amine group will easily form amide with a very small amount of NaOH catalysis. Additionally, only methyl alcohol is released as a byproduct.
“Is this hot sauce organic?”
“It’s handmade.”
What do you mean it hand made? 😐
nice one! 👍🏻
@@StardustSpiritDragon gloves get it gloves are like hands?
NileRed: Just let me take my gloves off.
Guy: W.. why are you putting those gloves in that beaker?
Don't worry I used my gloves its clean 😉
As someone who studies chemistry, massive hats off to NileRed for doing this and pulling through. Organic chemistry can be a nightmare but he made it! Congratulations!!
I think everyone studies chemistry
@@shaboingboing799 I don't study chemistry.
@@shaboingboing799 I never got to study chemistry
RUclips supports Dangerous Stuff,
even Hatepreachers.
Greg Locke is still online, after all.
But We CAN do somehting about it.
If you dont wanna be not-updated, then try the newest video of 'Belief It Or Not' and the 2 GOP-Videos of 'Some More News'. They are really, really informtive.
Not directly Science-related at all, i guess,
but the 'Spirit' of Science (for the lack of a better word) is right-here. This is It.
bruh he has a whole team behind him doing everything, hes just reading of script and doing the lab stuff
"Then I poured it all into a separatory funnel"
That should be on some new merch
Or “then I poured it into my vacuum filter”
I know right… Man did this like two dozen times
Or "I then had to distill the solution"
My new lab was littered with filthy separators funnels stashed in strange places and I said “NileRed’s been here”
HEXANES
At first, he was unsure whether to taste it. Then, he just casually shoots in methanol and then eats the sauce. That's what I call character development
watching him actually make the hot sauce in the same format and visual presentation as advanced chemistry was hilarious
i mean hey this is pretty advanced chemistry
i just sat here for an hour and six minutes and watched a man make hot sauce from gloves and vanilla and not once did I get bored, keep up the good work nile.
Nigel is a man of focus, commitment and sheer will. I once saw him make hot sauce in a lab… with gloves. With fuckin’ gloves.
And vanilla
and by "with gloves" we mean by turning gloves into hot sauce like some sort of alchemist, not as in he was wearing them while making the sauce (though he was wearing some, safety first)
@@youssefwaseem6248 that's literally what I was gonna say...
word for word...
@@Michaelonyoutub reference to the podcast
This is very similar to the experiment I saw in high school. It is the closest I have found. The one I saw collected the gasses separately and tested with flame and glowing splint. Then the experiment was performed again to rejoin the gasses with electricity. The only dissapointment I had was that the pipette tip was put under water, so it isn't clear that water did not get forced back up from the petri dish.
This man makes a single... single wing for an experiment. This is what I call commitment.
yes
Commitment aside that is just insane :D
What is a wing?
@@emmetlorenz4393 a chicken wing
@@PianoWireDasWire , ,, , k , ZZZ z x o,'x
Thanks for spending all this time to show us some cool chemistry.
Why your comment is marked with $10.00
@@Microplay-Interactive dont undestimate The Dollar man
@@Microplay-Interactive I think RUclips has introduced a tipping feature
@@Microplay-Interactive donation
He spent his life savings
I now have the utmost respect for firms who produce spicy sauce since they must purchase millions of gloves each year and spend hours following this guy's directions simply to produce a few bottles.
Actually a very common misconception, big companies don’t actually use plastic gloves. That was just for this experiment. They are too expensive, instead they use plastic cups to make the spice.
i once heard that they use raincoats but idk.
@@Charlie-tc7nq Unless that hot sauce is Da Bomb Beyond Insanity. They make it from used condoms.
Why use gloves when you could use plastic boxes
@@TomGallagherSuperboyBeyond little did we know all hotsauce producers are playboys
What's absolutely hilarious to me is the actual amount of switching stuff from one container to another and stirring that chemistry actually is. We had it right as kids
This man will turn you in to a pop tart if you call him a nerd
Hahaha best comment
Lol.
Worst comment ive ever read
@@capri_sunnn7935 i will unspokenly rizz your uncle
@@bruh_man124 tylko jedno w glowie mam koksu piec gram, odlediec sam
These are so packed with juicy information they aren't even skimmable. As soon as I find myself in front of a NileRed video I'm like well, looks like I'll be spending another hour on RUclips.
I hadn't noticed how long this video was until I read this, now I'm kinda scared
And also like: okay I'm about to learn at least 10 new things
@@familyguy1996iscool Know Sci Man Dan, Sci Show, Tier Zoo, Bluejay,
Prophet of Zod and Hbomberguy?
Those are some of my favorite 'smart' channel so i thought i share.
i have youtube premium so i listen to these while doing assignments in school lol
Nile Red 5 years from now;
"I was looking at a lizard, and it occurred to me that since most creatures are just mostly made of water and carbon, I could design my own sentient species"
John Hammond of Jurassic Park would be proud
"making a dinosaur from coca cola"
"I turned plastic gloves and lizards into hot sauce"
@The Red Sheep Bruh
"It has been stated that, broken down to its barest components, the average adult human body is comprised of Water (35 L), Carbon (20 kg), Ammonia (4 L), Lime (1.5 kg), Phosphorous (800 g), Salt (250 g), saltpeter (100 g), Sulfur (80 g), Fluorine (7.5 g), Iron (5 g), Silicon (3 g) and fifteen traces of other elements." -FMA wiki
Chemisty is just pure magic to me... Just wizards
Every time i hear him talk about bubbling it through something for insane amounts of time, i just have to think "who found this out?"
Like you sat down and went "yeah, let's bubble this through [thing] for 12 hours" and your chemist mate next to you goes "don't do that with [other thing], i waisted 12 hours of my life testing that last week"
Or how did they find out?!
And how do they find out which chemical they got for the first time? Like, Nile puts it into a machine that gives out a reading... but how did the reference reading was created in the first place?
Nile’s thought process for every new creation:
“I also wasn’t exactly sure how to do it, or if it would actually work”
I read this whilst he was saying those exact words
Same
i love how even when making the sauce portion of the hot sauce, he still treats it as he would any other experiment on his channel.
i want a cooking channel in this presentation format
Cooking is in essence just applied chemistry.
Yes hobpoooo o oh oooophooooohphoooooo bbbobbobb off ooo oooh bboo
@@lexicus1275 ChefRed
@@lexicus1275 possibly with some biology mixed in there if you're doing anything with yeast
interestingly, I have noticed a similarity with the vanillin being added. Some time ago I read about how certain spiders use venom containing vanillotoxins to activate the same receptors as we have for spicy pepper. I remember thinking at the time, "that's a strange name for a spicy neurotoxin..." but now it all makes sense!
The more you know....
You ever put vanilla extract in milk? Makes it spicy
@@hunterthompson6808 vanilla extract kindof is spicy honestly
@@_aa546 probably because of the alcohol
We don't have receptors for capsaicin, we just have existing receptors that misfire.
You know you're doing something right when you make a video like this and a person like me (who was a C-student in Chemistry 25 years ago) can follow along without feeling like an idiot.
if nilered ever comes on hot ones, he needs to bring this with him
He should synthesize this again specifically for the last dab. If he made a large enough batch, I think Sean might be willing to sell a few of the bottles as limited releases, so Nigel could get some extra funding outside of Patreon!
And spice it up even more
I think it's worth noting that First We Feast has less than three times as many subscribers as NileRed. I think NileRed deserves huge credit for building up such a huge following without having big name guests like Gordon Ramsey and Salma Hayek. People come here for the chemistry, but stay for the Nigel.
@@acartwright10 well, did you hear what he said in the video? this was an extremely long and arduous process that took him several months (and years to actually get to it) just for enough of the chemical for 2 bottles of hot sauce. i don't he can just "whip up some more"
@@acartwright10 While that would be really cool, selling it poses a mountain of legal obstacles.
To be honest, I have studied a lot of these reduction, hydrogenation and all these crazy organic reactions with amines, carbonyls and alcohols, and while writing the reactions in paper, it felt really easy but looking at what you had to do, it is really tough man. Maintaining the temperature to purifying it wow, you are amazing. Congratulations on this project.
You get used to it Rohan
These videos always manage to fit somewhere between pure comedy, wizardry, and extremely educational and I love it. Thanks for the laughs and knowledge Nigel!
Sleep aid
“That’s a good sauce!”
“What peppers did you put in it?”
Him:
“glove”
Things you normally don't hear Nile say: "this was pretty much the amount I expected" "occasionally just catch fire which we don't want". Grats on finally getting that reaction right
For me the quote that did it is: "it was a dirty brown."
Tbf, that's tend to come up alot, especially in older vid (usually it's something abt the yelding is bad due to wasteful step). The wilding out tend to be on short ot nileblue. NileRed with his long and detail oriented videos is alway a respectable chemist/scientist imo.
@@asdasd1111ish just good-natured ribbing. I'm used to NileRed shorts by now, where he literally made a fireball and played with it. I am genuinely happy and proud that this went well for him compared to old videos, shows he's improving. And I love that we got another longer video even if I can barely understand it with my smol brain
Friend: Damn what’s this sauce made of?
Nile: gloves and vanilla……
Friend: …
gluvsuhvanola whats that" no I said gloves and vanilla" 👁👄 👁 huh
Still a better recipe than Frank’s Red Hot lol
👍
Honestly, it would be believable coming from Nile of all people
friend : ☠
This guy is making chemistry sound more like alchemic transmutation honestly.
You do know how chemistry started right?
Good science is magical, there's such a strange relationship between truth and beauty (and I'm not talking about quarks)!
At least its not mixing charcoal and candles lol
@@Christer2222 at least its not mixing hydrogen with fire :)
@@Christer2222 at least it's not reaction of Polystyrene with gasoline and engine oil
“It’s pretty good! It’s right on the threshold of being completely inedible.”
This is actual fucking alchemy.
Imagine a wizard coming to solve your kingdom's hot sauce shortage in exchange for a million pounds of plastic gloves.
I wouldn't want to live in any fairy-tale kingdom if there wasn't enough hot sauce.
Lol same. Even though I’m barely able to handle chilli
@@daisiesofdoom that's why you call the alchemist
And vanilla, dont forget the vanilla.
Servants: My Liege! We don't have any hot sauces
NileRed: bring me my gloves and vanilla
imagine not being able to get vanilla sugar for your baking project because local chemist needed all of them for hot sauce 💀
“i coulda sworn they were there yesterday”
What's even better is that the store probably started stocking up on it thinking "man, I'm not sure why people are buying so many of these but we need to make sure we have them in stock" only for them to just start piling up when he finished his video.
@@dukeofthedance8062 I can just see the stocking manager getting fired over this then coming across those two videos years later and being like "holy shit, this man cost me my job" then he goes back to his boss and shows him and he's just like "yea, sure, you probably had your friend make these"
he needed the vanilla sugar to turn plastic gloves intro hot sauce. makes it more confusing
It's super easy to make vanilla sugar for baking though. Just get some regular granulated sugar and some vanilla beans. Open the vanilla beans (use the insides for something else if you want, they don't have to go into the sugar, you can still get the flavor from the empty husk!) and put the beans in with the sugar. Shake periodically. It just takes time for the vanilla to infuse with the sugar.
Nature: "Look, I spend millions of years evolving chili peppers!"
Nilered: "Hold my gloves."
Plus the thousands of years of patient hybridization from native American food scientists.
Naw... NileRad: Hold my grape soda... :P
Thats why only clowns believe in big bang and nothing creating everything and that you came from fish ... come on man anything is more belivable then that xD
@@slavplaysgames not really, and it’s called “The Big Bang Theory” for a reason man, it’s just a theory that hasn’t been 100% proven, but it has the most evidence, and I could say that everyone that believes in gods creating things because they were bored are clowns because anything is more believable then that.
@@tjailinht9412 Yeah I respect people who believes in creationism but those who call others clowns for believing a more believable theory are the true clowns.
"Yo bro what peppers did you use to make this"
"You wouldnt believe me"