Ania Jastreboff: The Transformative Obesity Drugs

Howie and Harlan are joined by Ania Jastreboff, a Yale endocrinologist and an expert on obesity medication, to talk about the remarkable range of diseases treated by drugs like Ozempic, Mounjaro, and Wegovy. Harlan discusses new Apple devices with the ability to detect sleep apnea and aid in hearing; Howie reports on outbreaks of polio in Pakistan, Afghanistan, and Gaza.
Links:
Apple and Health
“FDA clears Apple’s sleep apnea detection feature for use. Here’s how it works” (www.cnbc.com/2...)
FDA: “FDA Authorizes First Over-the-Counter Hearing Aid Software” (www.fda.gov/ne...)
“FDA approves some Apple AirPods to be used as hearing aids” (www.npr.org/20...)
National Council on Aging: Reasons for Low Hearing Loss Treatment (www.ncoa.org/a...)
Obesity Drugs
“Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity” (jamanetwork.co...)
“An Obesity Drug Prevents Covid Deaths, Study Suggests” (www.nytimes.co...)
“Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes” (www.nejm.org/d...)
“The New Anti-Obesity Drugs: What You Should Know” (health.clevela...)
Video: Oprah Winfrey and Ania Jastreboff, “What Exactly Is Obesity? A Yale Doctor Explains” ( • What Exactly IS Obesit... )
“Obesogenic environments and obesity: a comment on ‘Are environmental area characteristics at birth associated with overweight and obesity in school-aged children? Findings from the SLOPE (Studying Lifecourse Obesity PrEdictors) population-based cohort in the south of England’” (www.ncbi.nlm.n...)
“Oprah Takes on Weight Stigma in the Ozempic Era” (www.nytimes.co...)
“Once-Weekly Semaglutide in Adults with Overweight or Obesity” (www.nejm.org/d...)
Ania Jastreboff: “Tirzepatide Once Weekly for the Treatment of Obesity” (www.nejm.org/d...)
Ania Jastreboff: “Triple-Hormone-Receptor Agonist Retatrutide for Obesity-A Phase 2 Trial” (www.nejm.org/d...)
“Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity” (www.nejm.org/d...)
“Obesity drug black market thrives online in S. Korea” (www.chosun.com...)
“Novo Nordisk’s Wegovy Weight-Loss Drug Gets Approval in China” (www.wsj.com/he...)
“A Popular Weight Loss Drug Is Getting a Price Cut” (www.nytimes.co...)
Polio
Poliovirus outbreak in New York State, August 2022: qualitative assessment of immediate public health responses and priorities for improving vaccine coverage (www.ncbi.nlm.n...)
CDC: Vaccine-Derived Poliovirus (www.cdc.gov/va...)
WHO: “Humanitarian pauses vital for critical polio vaccination campaign in the Gaza Strip” (www.who.int/ne...)
Howard Forman Discusses Polio in Gaza on TikTok (www.tiktok.com...)
CDC: Progress Toward Poliomyelitis Eradication-Pakistan, January 2023-June 2024 (www.cdc.gov/mm...)
“Afghanistan risks polio outbreak as Taliban restricts women from delivering vaccines” (www.theguardia...)
“Polio eradication: the CIA and their unintended victims” (www.thelancet....)
Learn more about the MBA for Executives program at Yale SOM (som.yale.edu/p...) .
Email Howie and Harlan comments or questions. (mailto:[e-mail])