Marburg Virus Disease: The Dark Side of Ebola's Cousin | MVD | Viral Zoonotic Disease | Bats

Marburg Virus Disease (MVD) is a severe and often fatal illness caused by the Marburg virus, a member of the Filoviridae family, similar to the Ebola virus. It was first identified during an outbreak in Marburg, Germany, in 1967, and subsequent outbreaks have occurred in African countries.
The disease is primarily transmitted to humans through contact with infected animals, such as bats and non-human primates, and can then spread through direct contact with the blood, secretions, organs, or other bodily fluids of infected individuals.
The history of Marburg Virus Disease (MVD) dates back to 1967 when the first known outbreak occurred in the city of Marburg, Germany. The Marburg virus is a member of the Filoviridae family, and like other viruses in this family, it has a unique and distinctive structure.
The infectious form of the Marburg virus is called the virion. It is an elongated, filamentous, and pleomorphic (variable in shape) virus particle. The virion is approximately 800 nm in length and 80 nm in diameter.
The Marburg virus is considered a zoonotic virus. The natural reservoir of the virus is suspected to be bats, and human infections can occur through direct contact with infected bats or their excreta (e.g., saliva, urine, feces).
The initial symptoms of MVD are nonspecific and flu-like, making it challenging to diagnose in the early stages. Common symptoms include sudden onset of high fever, severe headache, muscle aches, weakness, fatigue, and general malaise.
MVD is often classified as a viral hemorrhagic fever due to its ability to cause bleeding and clotting abnormalities. As the disease progresses, patients may experience bleeding from various sites, both internal (e.g., gastrointestinal tract, lungs) and external (e.g., gums, nose).
MVD is believed to be transmitted to humans from infected animals, primarily bats and non-human primates. To prevent exposure, avoid direct contact with bats and their excreta, as well as wild animals that may be potential carriers of the virus.
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