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RojasLab
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Добавлен 24 ноя 2018
🧪 Welcome to RojasLab: Unleashing the Power of Chemistry Education! ✨
RojasLab is your ultimate destination for an immersive and enlightening journey through the fascinating world of chemistry. 🌐🔬 Dr. Rojas received his Ph.D. in chemistry from Massachusetts Institute of Technology (MIT) and is a chemistry professor at Georgia Tech. Years of teaching college students have led to him wanting to help a broader audience using the reach of RUclips.
📚 Tailored for students of all levels, our videos span the entire spectrum of chemistry classes. Whether you're diving into the basics of general chemistry, exploring the intricacies of organic chemistry, or navigating the advanced realms of inorganic chemistry, RojasLab is your dedicated guide. 🚀
🔬 What to Expect:
✅ Comprehensive tutorials for various chemistry courses
✅ Practical demonstrations of key principles
✅ Problem-solving guides and exam tips
✅ Insights into real-world applications of chemistry
RojasLab is your ultimate destination for an immersive and enlightening journey through the fascinating world of chemistry. 🌐🔬 Dr. Rojas received his Ph.D. in chemistry from Massachusetts Institute of Technology (MIT) and is a chemistry professor at Georgia Tech. Years of teaching college students have led to him wanting to help a broader audience using the reach of RUclips.
📚 Tailored for students of all levels, our videos span the entire spectrum of chemistry classes. Whether you're diving into the basics of general chemistry, exploring the intricacies of organic chemistry, or navigating the advanced realms of inorganic chemistry, RojasLab is your dedicated guide. 🚀
🔬 What to Expect:
✅ Comprehensive tutorials for various chemistry courses
✅ Practical demonstrations of key principles
✅ Problem-solving guides and exam tips
✅ Insights into real-world applications of chemistry
Mechanism Monday #6: Master Arrow Pushing!
In the 6th episode of Mechanism Monday, we'll break down complex organic chemistry reactions into easy-to-understand mechanisms. Each week, you'll get a detailed walkthrough of a different chemical transformation, complete with step-by-step guidance and practical tips.
In This Video:
Introduction to the Mechanism Monday series
Explanation of the importance of understanding reaction mechanisms
Detailed breakdown of a key organic chemistry reaction
Tips for mastering electron-pushing arrow notation
Common pitfalls and how to avoid them
Why Watch This Series?
Expert Insights: Learn from experienced chemistry educators.
Simplified Concepts: Complex reactions made easy with clear explanations.
I...
In This Video:
Introduction to the Mechanism Monday series
Explanation of the importance of understanding reaction mechanisms
Detailed breakdown of a key organic chemistry reaction
Tips for mastering electron-pushing arrow notation
Common pitfalls and how to avoid them
Why Watch This Series?
Expert Insights: Learn from experienced chemistry educators.
Simplified Concepts: Complex reactions made easy with clear explanations.
I...
Просмотров: 166
Видео
Symmetry in Chemistry: The Key to Unlocking Molecular Secrets!
Просмотров 15112 часов назад
Dive deep into the fascinating world of symmetry in inorganic chemistry with this detailed lightboard tutorial! In this video, you'll explore essential symmetry concepts that play a crucial role in understanding molecular structure and behavior. Whether you're a student preparing for exams or a chemistry enthusiast, this guide will help you master the key symmetry elements and operations. What ...
Mechanism Monday #5: Can YOU Solve This?
Просмотров 26916 часов назад
In the 5th episode of Mechanism Monday, we'll break down complex organic chemistry reactions into easy-to-understand mechanisms. Each week, you'll get a detailed walkthrough of a different chemical transformation, complete with step-by-step guidance and practical tips. In This Video: Introduction to the Mechanism Monday series Explanation of the importance of understanding reaction mechanisms D...
Nucleophiles and Electrophiles: The Key to Understanding Organic Reactions!
Просмотров 249День назад
Dive deep into the fascinating world of nucleophiles and electrophiles, crucial concepts in organic chemistry. Whether you're a beginner or looking to refine your skills, this video will help you master the fundamentals with ease. What You’ll Learn: ✅ Introduction to Nucleophiles and Electrophiles ✅ Understanding Curved-Arrow Notation for Electron Flow ✅ Common Examples and Characteristics of N...
Mechanism Monday #4: Test Your Organic Chemistry Knowledge!
Просмотров 30614 дней назад
In the 4th episode of Mechanism Monday, we'll break down complex organic chemistry reactions into easy-to-understand mechanisms. Each week, you'll get a detailed walkthrough of a different chemical transformation, complete with step-by-step guidance and practical tips. In This Video: Introduction to the Mechanism Monday series Explanation of the importance of understanding reaction mechanisms D...
Unlock the Secrets of Chair Conformations in Organic Chemistry!
Просмотров 25214 дней назад
🌟 In this chemistry tutorial, we delve into the world of chair conformations in organic chemistry. Whether you're a beginner or looking to refine your skills, this video will help you master the art of drawing chair conformations with ease. What You’ll Learn: ✅ How to Draw Chair Conformations ✅ Understanding Axial and Equatorial Positions ✅ Analyzing Monosubstituted Cyclohexane ✅ Exploring Disu...
Mechanism Monday #3: Simplifying Reaction Mechanisms for You!
Просмотров 51521 день назад
3rd episode of Mechanism Monday, we'll break down complex organic chemistry reactions into easy-to-understand mechanisms. Each week, you'll get a detailed walkthrough of a different chemical transformation, complete with step-by-step guidance and practical tips. In This Video: Introduction to the Mechanism Monday series Explanation of the importance of understanding reaction mechanisms Detailed...
The Ultimate Guide to Newman Projections: Conquer Conformational Analysis!
Просмотров 12221 день назад
🌟 Welcome to [Your Channel Name]! In this video, we delve into the fascinating world of Newman projections and conformational analysis in organic chemistry. Whether you're a student preparing for exams or a chemistry enthusiast, this comprehensive guide will help you master these essential concepts with ease. 🧪🔍 What You’ll Learn: ✅ How to Draw Newman Projections ✅ Conformational Analysis of Et...
Mechanism Monday #2: Step-by-Step Mechanisms Explained!
Просмотров 50828 дней назад
In the 2nd episode of Mechanism Monday, we'll break down complex organic chemistry reactions into easy-to-understand mechanisms. Each week, you'll get a detailed walkthrough of a different chemical transformation, complete with step-by-step guidance and practical tips. In This Video: Introduction to the Mechanism Monday series Explanation of the importance of understanding reaction mechanisms D...
Ligand Field Theory: Understanding Coordination Complex Electronic Structures!
Просмотров 275Месяц назад
🌟 Embark on a journey into the heart of coordination chemistry as we explore the fascinating realm of ligand field theory, a powerful framework for understanding the electronic structures and properties of transition metal complexes. 🧪🔍 💡 In this comprehensive guide, we'll delve deep into the principles of ligand field theory, uncovering how the interactions between transition metal ions and su...
Mechanism Monday #1: Master Organic Chemistry!
Просмотров 963Месяц назад
Welcome to the inaugural episode of Mechanism Monday! In this exciting new series, we'll break down complex organic chemistry reactions into easy-to-understand mechanisms. Each week, you'll get a detailed walkthrough of a different chemical transformation, complete with step-by-step guidance and practical tips. In This Video: Introduction to the Mechanism Monday series Explanation of the import...
Everything You Need to Know About Naming Coordination Complexes!
Просмотров 119Месяц назад
🌟 Dive into the intricacies of coordination chemistry with our educational video! Join us as we unravel the complexities of coordination complex nomenclature, providing you with a comprehensive guide to naming these fascinating chemical entities. 🧪🔍 💡 In this comprehensive tutorial, we'll demystify the rules and conventions governing the naming of coordination complexes, from simple mono- and p...
Resonance Explained: A Must-Know for Organic Chemistry!
Просмотров 283Месяц назад
This video will help you master resonance structures and enhance your understanding of molecular stability and reactivity. 🧪✨What You'll Learn: ✅ Introduction to Resonance ✅ Using Curved Arrows for Drawing Resonance Structures ✅ Formal Charges in Resonance Structures ✅ Drawing Resonance Structures via Pattern Recognition ✅ Assessing the Relative Importance of Resonance Structures ✅ Understandin...
Tips and Tricks for Drawing Organic Molecules Like a Pro!
Просмотров 613Месяц назад
Are you struggling with molecular representations in organic chemistry? 🌟 Look no further! In this comprehensive tutorial, we'll guide you through the essential techniques to master drawing molecules, from basic Lewis structures to advanced three-dimensional bond-line structures. Whether you're a student preparing for exams or a chemistry enthusiast, this video has got you covered! 🧪📘 What You'...
Master Organic Chemistry 2 with Every Reaction You Need to Know!
Просмотров 1,2 тыс.2 месяца назад
Are you ready to master Organic Chemistry 2? 🌟 In this ultimate guide, we cover all the crucial reactions you need to know to excel in your course and ace your exams. From fundamental mechanisms to advanced concepts, we've got you covered. 🧪📘 What You'll Learn: ✅ Diels-Alder Reactions: Dive into the cycloaddition reaction that forms six-membered rings, a cornerstone in organic synthesis. ✅ Keto...
Unlock the Secrets of the 18-Electron Rule: Master Coordination Chemistry Today!
Просмотров 2732 месяца назад
Unlock the Secrets of the 18-Electron Rule: Master Coordination Chemistry Today!
Unlock the Secrets of Multistep Synthesis: Transform Simple Molecules into Complex Compounds!
Просмотров 2,8 тыс.2 месяца назад
Unlock the Secrets of Multistep Synthesis: Transform Simple Molecules into Complex Compounds!
Mastering Organic Synthesis: Multi-Step Reactions & Retrosynthetic Analysis Explained!
Просмотров 1,4 тыс.2 месяца назад
Mastering Organic Synthesis: Multi-Step Reactions & Retrosynthetic Analysis Explained!
Master Claisen Condensations and Conjugate Additions! Alpha Carbon Chemistry Part 2
Просмотров 4672 месяца назад
Master Claisen Condensations and Conjugate Additions! Alpha Carbon Chemistry Part 2
Unlocking the Secrets of Alpha Carbon Chemistry: Master Enols and Enolates NOW!
Просмотров 5923 месяца назад
Unlocking the Secrets of Alpha Carbon Chemistry: Master Enols and Enolates NOW!
Exploring Hard-Soft Acid-Base Theory of Lewis Acids and Bases
Просмотров 1353 месяца назад
Exploring Hard-Soft Acid-Base Theory of Lewis Acids and Bases
ALL the Reactions of Carboxylic Acid Derivatives: Acid Chlorides, Esters, Anhydrides, and more!
Просмотров 1,7 тыс.3 месяца назад
ALL the Reactions of Carboxylic Acid Derivatives: Acid Chlorides, Esters, Anhydrides, and more!
Carboxylic Acid Derivatives: Structures, Names, and Reactivity
Просмотров 3363 месяца назад
Carboxylic Acid Derivatives: Structures, Names, and Reactivity
Carboxylic Acids: Nomenclature, Properties, and Synthesis!
Просмотров 4243 месяца назад
Carboxylic Acids: Nomenclature, Properties, and Synthesis!
Benzylic Reactions, Heteroaromatic Compounds, and Birch Reductions Demystified!
Просмотров 5233 месяца назад
Benzylic Reactions, Heteroaromatic Compounds, and Birch Reductions Demystified!
Electrocyclic Reactions and Sigmatropic Rearrangements: A Deep Dive into Organic Chemistry!
Просмотров 3533 месяца назад
Electrocyclic Reactions and Sigmatropic Rearrangements: A Deep Dive into Organic Chemistry!
Mastering Peptide Synthesis: Coupling Reagents, Protecting Groups, and Solid-Phase Peptide Synthesis
Просмотров 7393 месяца назад
Mastering Peptide Synthesis: Coupling Reagents, Protecting Groups, and Solid-Phase Peptide Synthesis
Reviewing ALL Organic Chemistry 1 Reactions with Practice Problems!
Просмотров 6264 месяца назад
Reviewing ALL Organic Chemistry 1 Reactions with Practice Problems!
Reviewing ALL of Organic Chemistry 1 with Practice Problems!
Просмотров 5334 месяца назад
Reviewing ALL of Organic Chemistry 1 with Practice Problems!
Amino Acids: Everything You Need to Know
Просмотров 2834 месяца назад
Amino Acids: Everything You Need to Know
Nice chemistry sir
Thanks for the kind words!
Thank you!! you’re videos are great for people like me who don’t study chem in college but love it! Keep up the amazing work!!
Thanks so much for saying that! It means a lot to me and I’m glad you’re enjoying them!
Do you make these videos because for the sole purpose of education?
Yeah! Many of them, I use for my own real classes I teach at Georgia Tech, and for the love of chemistry!
@@rojaslab that's fantastic, the work you're doing is necessary, and a public good. Thank you for making it available
How did you do? I'd love to hear your proposals for next week's mechanism so drop them down below! Subscribe for more chemistry content, and hit the notification bell to stay updated! #ScienceCommunity #MechanismMonday #OrganicChemistry
Am not seeing the nomenclature at 14:07. How do we know (from the name) the heptane is not attached to N at C-4? It could still be (R)-N-ethyl-6-methylheptanamine...? Thanks!
Do more about group theory.
Thanks for the suggestion! I’m working on 2 group theory videos right now! Coming soon!
thanks man helped a bunch!
Thanks, Nathan! This was like the first video I ever made so I hope you find other ones even MORE helpful!
Very educative video. Good job
That’s so nice! Thank you!
Hello good sir ❤ please don't stop enlightening us we do really need the way u explain ❤ keep it going 🎉
That’s such a lovely compliment! Thank you so much!
Nice vidio❤.
Ayyyy! Thank you! 💕
If you enjoyed this video, don't forget to give it a thumbs up, subscribe for more educational content, and hit the notification bell to stay updated! Have questions or specific topics you'd like me to cover? Drop them below, and let's keep the chemistry conversation going! #ScienceCommunity #LearningTogether #InorganicChemistry
is 4 carbon ring compound is stable?
Yes! In fact, it’s in one of my favorite cancer drugs! cis-Diamminedichloroplatinum(II) (cisplatin) and cis-diammine-1,1-cyclobutane dicarboxylate (carboplatin) are widely used in chemotherapy, and are particularly effective in the treatment of testicular, ovarian, head, neck and non-small cell lung cancer.
I really enjoy these videos but it’s really disappointing if one can’t get to the right solution because the starting material was drawn incorrectly. The double bond was missing in the first figure. Are the double bonds correct in the product of the new exercise? If I draw the mechanism with a ring opening of the formed [2.2.0]-bicyclohexanone I get the double bonds in different positions
Hi Robin! Like most people, I’ve definitely made mistakes in my past. However, this go around I believe everything is correct and I’d encourage you to check again! Importantly for your double bonds on the 2nd one, it may be possible that your resonance structure is energetically equivalent, even if not identical!
Great video! I've seen multiple of your videos, frankly and respectfully you need to work on your drawings because after a few steps it becomes so crowded and I can't tell what's going on by then.
Thanks for the respectful feedback, Anddie! I’ll work on making things less cluttered in the future!
Yeaaah mechanism monday 🕺
Haha! Love it! 💃🏼
Your clip is pretty interesting. Because of busy schedule, i could not watch fully but i still liked. Hope you successfull
Ayyy I appreciate the engagement for the RUclips algorithm! You’re the best!
First a claisen condensation reaction takes place which forms a bicyclic intermediate and the loss of ethanol. Then the acidic alpha hydrogen, in the middle of the two carbonyls, is deprotonated forming a new alkene that breaks the C-C bridge. The electrons from the broken bond moves towards the carbonyl that was once an ethyl ester. This creates the six membered ring and the alkoxide giving the final product.
Ayyyy you love to see it! Absolutely crushed it!
in the last step when we have the ring with oh group we can do an elimination reaction if we consider it to be done in acidic conditions
Great idea!
thank you for helping me in becoming less of a noob in chemistry :)
Haha. We all started somewhere! Thank YOU for watching!
I have my first chemistry exam in med school tomorrow and this helped a lot! Thank you
Whaaaat! Good luck, future Doctor!
Thank you for the video. Can the alkoxide also react as an electrophile at the carbon which is attached to oxygen?
Not likely since that would kick off an O(-2) ion, which is a very poor leaving group.
That’s an awesome question. And given that an alkyl halide can, by extension one would think yes. However, I can’t think of any immediate examples where it ever does behave as an electrophile. Same for alcohols actually. I THINK it’s because for alkyl halides, the halide can leave afterwards keeping carbon from making 5 bonds. But in the alkoxide, that’s not possible!
I was thinking that once one of the amines was protonated, a sn2 attack of water would happen, and then a proton transfer, then the lone pairs from oxygen would kick off the C-N sigma bond. This would then repeat for the adjacent nitrogen obtaining formaldehyde. But it would make sense that the neighboring nitrogen would kick the ammonium off first since it's intramolecular.
That’s a good point. In truth, without experimental evidence we can’t actually eliminate your proposal either though. In truth, all mechanisms are really just guesses that may be supported or merely theoretical
@@rojaslab I think both are possible, but the mechanism where the lone pair on the nitrogen become delocalized probably provide a kinetic route due to the proximity, intra vs inter.
@@maxwellzimmerman4835 Agreed. Fun to think about all the possibilities though and go down the rabbit hole!
Your teaching is excellent in all videos but this video you draw the wrong urotropin structure this one change
Yes, you are right! I’ll be sure to get it right on the next one!
My favourite serie of videos on youtube! Keep it up !
Ayyyy!!! I appreciate that! If you’ve got any doozies for the community, please let me know!
Hi, cool video, but the structure of Urotropin that you draw in blue is wrong. The lower nitrogen only has two bonds to cabons while it should have three.
Thanks for pointing that out, Stefan! I don't know what's more impressive, your piano skills or the fact that you knew that molecule is called Urotropin!
@@rojaslab No worries. I am a org. chem Prof. myself. Your videos are a wonderful educational resource!
@@TheStefanSchramm Whaaaat! Small world. In truth, I'm an inorganic chemist. My University asked me to teach organic 2 this summer for the first time, which sparked the videos. Thanks for keeping me honest!
How did you do? I'd love to hear your proposals for next week's mechanism so drop them down below! Subscribe for more chemistry content, and hit the notification bell to stay updated! #ScienceCommunity #MechanismMonday #OrganicChemistry
How did you do? I'd love to hear your proposals for next week's mechanism so drop them down below! Subscribe for more chemistry content, and hit the notification bell to stay updated! #ScienceCommunity #MechanismMonday #OrganicChemistry
5:53 why does another EtOH have to deprotonate it? oxygen can only have 2 bonds so i figure it deprotonates itself & could just bubble out as H2.
That's an awesome question! Typically, protonated alcohols are proposed for mechanisms with regularity. Also, remember, that when ethanol is used as a solvent, there are billions and billions of ethanol molecules swimming around the reaction mixture so proton transfers can happen with relative ease.
It is mCPBA
Extra points if you know what all the letters stand for!
@@rojaslab hehe i work with it 😏
@@bigseleba That's cool! I've never done an epoxidation. I have started with epichlorohydrin though with the pre-installed epoxide.
@@rojaslab not exactly pleasant reagent. You never know the exact purity of it without a titration, also not the easiest work-up
That was really cool! Is there a particular name for this specific transformation?
I don’t think this one does classify as a named reaction, but if you stick around I think in the next few weeks of Mechanism Monday, we’ll have a few named reaction examples!
@@rojaslab Ah, thanks for letting me know!
This is great, thanks. Is it *possible* that instead of Michael addition we might get imine formation at the carbonyl carbon with the same result?
This is an excellent question. When you draw it out yourself, you form the imine… then what happens?
Also, how the heck did you BOLD a word on RUclips?! I didn’t even know that was possible!
@@rojaslab OK, I drew a picture. What I have is imine N acquiring transient partial + charge by associating with H on water. This partial + charge allows collapse of imine double bond into C2-C3 (your numbering at 0:38) and pulls C3-C4 e- density toward the N, closing ring. Maybe have to add heat? Maybe it does not work?
@@eastofthegreenline3324 Sounds like you're crushing it!!! That's great insight!
@@rojaslab Thanks for getting back! Very enjoyable series!
Hi Dr. Rojas another fantastic video! Just curious, I might be mistaken, but should there be an extra alkyl carbon in the reductive amination practice problem solution? Thank you so much again!
You're absolutely right!! What a great catch!
Like this, thank you 😄
Ayyy! You da best, Pei! Glad you liked it!
❤
💕
Love this! I'll see you every Monday until I finish my 2nd year in Chemistry.
My hope is that you’ll fall in love with chemistry and stick around forever!
What is it called, is it possible to eat it?
True story, a friend in my lab used to take a small sample of every chemical he made and taste it. Not illegal, but definitely frowned upon!
Great Video! Very informative for the MCAT!
Haha. You da man Vikram!
Good video, well understood,, Do more topics❤.
Thank you so much! I promise to keep going!
Hey broo ur a nice teacher Really loving ur teaching skills ❤
Ah that’s so nice of you! Thank you! If you ever want a special topic, please just let me know and I’m happy to make it for you!
If you enjoyed this video, don't forget to give it a thumbs up, subscribe for more chemistry content, and hit the notification bell to stay updated! Have questions or specific topics you'd like me to cover? Drop them below, and let's keep the chemistry conversation going! #ScienceCommunity #LearningTogether #OrganicChemistry
I like your very clear videos, mechanisms are well explained, thanks !
I’m so glad to hear you found value in the videos! Thank you so much for the kind words!
Michael addition of amine, proton transfer enol tautomerization, intramolecular imine condensation, then an elimination reaction to form the olefin.
Stay tuned for next week to find out! Also, random ? I also learned the term “olefin” but it’s since been replaced by “alkene” and I’m curious where you learned it!
@rojaslab oh that's what my ochem teacher would call alkenes. I guess it kinda stuck around
Hmm next week's vaguely reminds me of a robinson annulation analog- Michael addition, intramolecular ring forming reaction... not sure how I'd go about it to form a nitrogen heterocycle though
Sounds like you’re on the right track! I bet if you tried drawing it out you could figure out the key!
Now do a retrosynthesis of the molecule 😅
🤣 I’ll put it on my students’ next exam and give you credit!
Oh, next week’s looks cool! I see the Michael addition but what comes next?
Great insight! Definitely in the right track!
I'm not a chemist, but I find your lessons very educational, and chemistry is something I've had an interest in for a while. Maybe I'll go to school for it at some point
That's so great to hear! Fun fact, I didn't go back to college until I was 24 and graduate school until I was 28. I had a friend getting his Ph.D. in chemistry that started in his 30s. It's never too late! I'm glad you're here!
How did you do? I'd love to hear your proposals for next week's mechanism so drop them down below! Subscribe for more chemistry content, and hit the notification bell to stay updated! #ScienceCommunity #MechanismMonday #OrganicChemistry
Bro you were close to demonetization with the 1-phenyl-2-aminopropane 😂
Lmao! I’m so glad someone noticed. Gotta spice it up sometimes!
Hey, I loved the video! I do have a few question, though. At around 8:20, wouldn't the but-Li also attack the electrophilic carbon on the Carbonil group? I heard that ButylLithium, unlike an organocuprate (Gilman Reagent), is a hard nucleophile, meaning that it is less likely to attack a soft electrophile like a double bond and more likely to attack a harder electrophile like the electrophilic carbon of the Carbonil group. Also, at any point the nucleophilic intermediate could attack the electrophilic carbon on the Carbonil group, ending the polymerization reaction right there(unless the negatively charged oxygen could act as a nucleophile and attack another double bond or electrophilic carbon, which would lead to the formation of a completely different polymer). For those reasons I thought that a cationic polarization would be better suited for this particular polymer as it didn't encounter such problems. Having said that, the main problem that the cationic polarization would encounter is the fact that the intermediate would not be as stable as the one from the anionic polymerization, as the aldehyde group is an EWG, this would probably slow down the rate at which the reaction proceeds significantly, maybe even making the whole process unviable. Do You think that it could be done with a cationic one as opposed to the one shown in the video? I'd love to hear your thoughts on this as I'm not that knowledgeable about this topic just yet. But either way, thanks for this amazing content!
Excellent questions Felipe! You're absolutely right that butyllithiums typically do 1,2 additions, instead of 1,4 additions. This is excellent insight. I think, ultimately, you're right that many side or competing reactions are possible, which means that you'd likely end up with a variety of products in the solution. This is often the problem with polymerization reactions and why it's such an active area of research!
@@rojaslab I see, thanks for your response!
Hey, this video is really cool. At 9:30 I would have added that the sulfo group is withdrawing electron density in the orto and para positions due to its resonance structures.
Excellent point!