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ECETOC
Добавлен 5 янв 2012
ECETOC is the centre for chemical risk assessment. We are a platform for scientists from industry, academia and regulatory bodies who collaborate towards safer chemicals policies with science at their core.
Exploring best practices in building qAOPs
AOPs are scientific ‘roadmaps’ that connect the dots between an initial molecular exposure to a substance or a stressor and any eventual harm that may occur to living organisms or ecosystems.
Quantitative AOPs (qAOPs) allow scientists to use numbers and models to make predictions about how a living system will respond to different amounts of a chemical - and so predict how likely, or how severe any adverse outcomes may be.
Toxicologists, biologists, and computational modellers gathered at a workshop organised by ECETOC to discuss how to develop and integrate quantitative Adverse Outcome Pathways (AOP) into EU chemical safety assessments. The workshop focused on three questions on the huma...
Quantitative AOPs (qAOPs) allow scientists to use numbers and models to make predictions about how a living system will respond to different amounts of a chemical - and so predict how likely, or how severe any adverse outcomes may be.
Toxicologists, biologists, and computational modellers gathered at a workshop organised by ECETOC to discuss how to develop and integrate quantitative Adverse Outcome Pathways (AOP) into EU chemical safety assessments. The workshop focused on three questions on the huma...
Просмотров: 212
Видео
Maternal thyroid hormone (T4) imbalance and neurodevelopmental effects in the progeny
Просмотров 2888 месяцев назад
An ECETOC Task Force has studied potential links between endocrine disrupting effects chemicals of chemicals on the thyroid during pregnancy and breastfeeding - and what consequences these could have on the neurodevelopment of the baby. The work resulted in peer-reviewed manuscripts, published in Critical Reviews in Toxicology between 2020 and 2023, and in a tiered testing and assessment scheme...
Three-tiered approach for standard information requirements for polymers requiring registration
Просмотров 3669 месяцев назад
An ECETOC Task Force has proposed a three-tier approach to information requirements for risk assessment of polymers. The proposal ensures that animal testing is only used as ‘a last resort’, while still ensuring the quality of data for the risk assessment. Polymers cover a broad spectrum of generally very large molecules, including e.g. cellulose, waxes, and resins. They are also constituents o...
TRA Worker Tool v3.2
Просмотров 3229 месяцев назад
The latest version of the TRA Worker Tool is available now! Click on www.ecetoc.org/tools/tra-main/tra-download/ to download it - both in the updated Integrated Module or in a new standalone version. Users Guides for the TRA tools, as well as a revised FAQ, are also available for download at at www.ecetoc.org/tools/tra-main/tra-faq/. As mentioned in the video, updates concern the following PROC...
Health concerns for low tonnage chemicals and opportunities for NAMs
Просмотров 4810 месяцев назад
Currently, information requirements for chemicals according to the EU REACH regulation are based on the annual tonnage of production/import of a specific chemical into the EU. This approach, though pragmatic, does not take into account the potential levels of exposure for humans of that chemical substance. Exposure depends on how the chemical is used, and it could be high and/or prolonged regar...
What is persistence?
Просмотров 484Год назад
What does it mean when we say that a chemical is persistent? And why does it matter if it is? To get some answers, watch this short video developed in collaboration with ECETOC's "Moving persistence in the 21st Century" platform and FuelsEurope. For more information, visit www.ecetoc.org and tinyurl.com/bde2wx46.
Including georeferenced data to improve ecological relevance of chemical risk assessment
Просмотров 152Год назад
What could be the potential benefits of using georeferenced data in chemical risk assessment? What are the current limitations? Read ECETOC's report doi.org/10.1016/j.ecoenv.2022.114143 to find out how - Understanding of when and where chemical exposure and species co-occur improves risk assessments and makes mitigation more efficient. - Use of geo-referenced data enables the influences of envi...
Putting the CF4Polymers into practice: Cationic polymers
Просмотров 642 года назад
How does ECETOC CF4Polymers work in practice? Let's look at a case study on cationic polymers, presented at the 2022 SETAC Europe Conference
Considerations & Examples for Grouping of Polymers
Просмотров 752 года назад
ECETOC Conceptual Framework for Polymer Risk Assessment (CF4Polymers) explained at the 2022 SETAC Europe Conference. For more information visit: www.ecetoc.org
Assessing the safety of polymers: Examples of grouping approach
Просмотров 7172 года назад
Polymers are currently being reconsidered in the context of regulatory programmes. To help with this process, an ECETOC Task Force has looked at existing approaches with the aim of developing a framework for polymer risk assessment, i.e. the CF4Polymers (more info available at www.ecetoc.org/taskforce/assessing-human-health-environmental-safety-polymers/). One of the key steps identified in thi...
Developing a new paradigm to assess degradation potential of chemicals
Просмотров 643 года назад
A presentation at the 2020 SETAC online conference from the ECETOC Task Force "Moving persistence (P) into the 21st century'
Increasing ecological relevance of chemical risk assessment using geospatial approaches
Просмотров 743 года назад
An ECETOC Geospatial Approaches Task Force presentation for the 2021 SETAC EU Conference.
heatDB
Просмотров 4063 года назад
Check out the most comprehensive database on human exposure data and tools and submit new resources today.
What does it mean for you to be a woman in science?
Просмотров 1014 года назад
#ScienceChats with Amelie Ott : Kicking off a science career This video represents the speaker current view of the state of science and does not necessary reflects the policy of ECETOC Amelie Ott (Researcher in Environmental Engineering, Newcastle University)
What is your advice to aspiring young scientists ?
Просмотров 964 года назад
#ScienceChats with Amelie Ott : Kicking off a science career This video represents the speaker current view of the state of science and does not necessary reflects the policy of ECETOC Amelie Ott (Researcher in Environmental Engineering, Newcastle University)
How can we communicate about science today?
Просмотров 1015 лет назад
How can we communicate about science today?
What role does chemistry have to play in building a better future?
Просмотров 1245 лет назад
What role does chemistry have to play in building a better future?
What is the value in looking to nature when seeking to solve human problems?
Просмотров 585 лет назад
What is the value in looking to nature when seeking to solve human problems?
Mark Pemberton and Jim Bridges on Quantitative Weight of Evidence at ECETOC 'Omics Workshop
Просмотров 1867 лет назад
Mark Pemberton and Jim Bridges on Quantitative Weight of Evidence at ECETOC 'Omics Workshop