BioTechniques
BioTechniques
  • Видео 60
  • Просмотров 280 287
Engineering organoid models for cancer research
Get more from the In Focus on organoid models for cancer research here: www.biotechniques.com/in-focus/sartorius_ocrif_organoids-for-cancer-research/
Advanced cell-based approaches, such as 3D cell culture and 2D stem-cell models, are increasingly used to create models of human diseases, such as cancer, allowing researchers to study disease development, progression and pathogenesis in a controlled environment.
This video, part of our In Focus on organoids for cancer research, sponsored by Sartorius, introduces the two main types of organoids used in cancer research and the processes deployed to engineer them from different cell sources.
Animation by Kristian Baycroft-Willmott.
Просмотров: 136

Видео

Introducing next-generation antibodies
Просмотров 1,9 тыс.5 месяцев назад
Get more from the In Focus here: bit.ly/3vAb9A6 Including an infographic on next-generation antibodies for therapeutic applications: bit.ly/41Yqk2c And a podcast detailing the latest developments in antibody technologies: bit.ly/4aVo7sr Leading our In Focus on next-generation antibody therapeutics, this video details the three key categories of this next generation: bi-specific antibodies, anti...
Pathogen-agnostic surveillance with nanopore sequencing
Просмотров 1846 месяцев назад
Get more from the In Focus here: bit.ly/47eNxOu Including an infographic on influenza surveillance: bit.ly/3GUkdSQ And a podcast on wastewater surveillance: bit.ly/3RUoFr8 Many approaches for identifying pathogens, such as PCR, typically rely on looking for a specific region by assaying small, highly conserved genomic regions. However, metagenomic approaches sequence all genetic material in a s...
Characterizing 3D cell culture models
Просмотров 3417 месяцев назад
Get more from the In Focus here: bit.ly/46zz93i Including an infographic on how to characterize organoids: bit.ly/3sKLCmC And an interview with top tips to optimize your 3D cell culture workflows: bit.ly/46qN77p Despite the potential for 3D cell cultures to advance basic, translational and clinical research, there are barriers that prevent their optimization. This video explores the challenges ...
Single-cell analysis with nanopore sequencing
Просмотров 6447 месяцев назад
Get more from the In Focus here: bit.ly/3MwGJnP Including an infographic on the use of single-cell analysis to investigate cancer: bit.ly/47jAvQn And a podcast on investigating leukemia: bit.ly/3QvINh0 The tumor microenvironment is complex and continuously evolving as cancer cells grow and divide in an uncontrolled manner. Characterizing the transcriptome enables a deeper understanding of the p...
An introduction to surface plasmon resonance
Просмотров 8 тыс.7 месяцев назад
Get more from the In Focus here: bit.ly/47qhVGp Including an infographic on how to measure molecular interactions: bit.ly/47o0Tsu And a podcast on surface plasmon resonance: bit.ly/462s5vF Surface plasmon resonance (SPR) is a real-time, label-free optical technique used to detect and quantify molecular interactions. SPR has important applications in drug discovery and development and has many a...
The dangers of mycoplasma contamination
Просмотров 7909 месяцев назад
Get more from the In Focus here: bit.ly/3ZxU7O5 Including an infographic on how to prevent mycoplasma contamination: bit.ly/3PBUVwD And an interview on how to detect mycoplasmas in the lab: bit.ly/3PtPGPq Cell cultures are utilized for various purposes including studies exploring cell proliferation and the production of biologically active substances. They play a vital role in application devel...
Introducing iPSCs for cell and gene therapy
Просмотров 90310 месяцев назад
Get more from the In Focus here: bit.ly/3QAufia Including an infographic with tips for success in iPSC-derived cell therapy development: bit.ly/455lCjK And an interview on tips and technologies for the development of iPSC-derived cell therapies: bit.ly/3qorrdd Introducing our In Focus on iPSCs for cell and gene therapies, this video explores the history of iPSCs, their adaptability and the work...
Reproducibility of 3D cell cultures
Просмотров 2,6 тыс.11 месяцев назад
Discover more from the In Focus here: bit.ly/3Q3Byyp Including an infographic with tips and tricks for pipetting 3D cell cultures: bit.ly/3pLBHfm And a podcast on preparing 3D cell cultures: bit.ly/3K44FOr Although the use of 3D cell cultures is growing, reproducibility remains an issue in the field. One reason for this is that preparing 3D cell cultures can be technically challenging, so the c...
An introduction to CAR-T and CAR-NK cell therapy development
Просмотров 5 тыс.11 месяцев назад
Discover more from the In Focus here: bit.ly/3DksJst Including an infographic on CAR-T versus CAR-NK: bit.ly/3OjxtDZ And a podcast on CAR-T and CAR-NK therapies: bit.ly/3O2D1Cq Cell therapy is an emerging and exciting field within biotherapeutics, offering potential treatments for cancers and autoimmune diseases. In this short animated video, we introduce you to two chimeric antigen receptor (C...
What is organ-on-a-chip technology?
Просмотров 14 тыс.Год назад
Discover more from the In Focus here: bit.ly/3CGC79A Including an infographic with top tips for integrating organ-on-a-chip technology into your workflow: bit.ly/3pjA4VS And a podcast on organ-on-a-chip technologies: bit.ly/3NJZh5f How do human cells form organ and tissue replicas in vitro that can be interconnected to facilitate organ crosstalk? How does the organ-on-a-chip (OOC) technology de...
Multiplex analysis of the tumor microenvironment
Просмотров 2,5 тыс.Год назад
Discover more from the In Focus here: bit.ly/46mjp4q Including an infographic on multiplex immunofluorescence technologies: bit.ly/3CQ502V And a podcast on discovering new insights with spatial technologies: bit.ly/43bupPH Introducing our In Focus: Multiplex immunofluorescence for cancer research, this video provides an introduction to the tumor microenvironment, the complex interplay of the ce...
An introduction to gene expression analysis
Просмотров 5 тыс.Год назад
Discover more from the In Focus here: bit.ly/3NcixrD Including an infographic on endogenous control selection in gene expression studies: bit.ly/43lhV91 And a podcast on gene expression analysis: bit.ly/3NcizQh Gene expression analysis plays a critical role in candidate preclinical safety and toxicity screenings as well as in monitoring therapeutic efficacy and off-target effects to ensure biol...
Introducing long-read sequencing for metagenomics
Просмотров 5 тыс.Год назад
Discover more from the In Focus here: bit.ly/43C1G7a Including a podcast on long-read sequencing, metagenomics and the microbiome: bit.ly/3WLkvlT Discover how long-read sequencing is changing the game in metagenomic studies designed to interrogate both host and environmental microbiomes. This video provides an introduction to this topic, covered in further depth in our In Focus, supported by Zy...
An introduction to lab automation
Просмотров 5 тыс.Год назад
Discover more from the In Focus here: bit.ly/3YpSOiB Including a podcast on automation tips and challenges: bit.ly/3lBFetS Introducing our In Focus on lab automation, this video explores automation using PCR as an example. We look at the benefits of automation, the differences between a manual and automated PCR workflow, and if you should consider integrating automation into your lab. Animation...
Sequencing for conservation
Просмотров 3,8 тыс.Год назад
Sequencing for conservation
An introduction to cell-line development
Просмотров 12 тыс.Год назад
An introduction to cell-line development
An introduction to Droplet Digital PCR
Просмотров 14 тыс.Год назад
An introduction to Droplet Digital PCR
Profiling the microbiome
Просмотров 3 тыс.Год назад
Profiling the microbiome
An introduction to organoids
Просмотров 6 тыс.Год назад
An introduction to organoids
Introduction to single domain antibodies
Просмотров 8 тыс.Год назад
Introduction to single domain antibodies
Comprehensive genomic profiling for cancer
Просмотров 3,1 тыс.Год назад
Comprehensive genomic profiling for cancer
3D cell cultures: improving drug candidate testing
Просмотров 12 тыс.Год назад
3D cell cultures: improving drug candidate testing
Viral infections, epigenetics and cancer
Просмотров 9 тыс.Год назад
Viral infections, epigenetics and cancer
Introducing bioinformatics workflow management
Просмотров 7 тыс.2 года назад
Introducing bioinformatics workflow management
Introducing cell-free nucleic acids
Просмотров 8 тыс.2 года назад
Introducing cell-free nucleic acids
Modeling fatty liver disease in vitro
Просмотров 18 тыс.2 года назад
Modeling fatty liver disease in vitro
Standardizing Microbiome Data
Просмотров 16 тыс.2 года назад
Standardizing Microbiome Data
Epigenetics and aging
Просмотров 11 тыс.2 года назад
Epigenetics and aging
Single-cell sequencing
Просмотров 17 тыс.2 года назад
Single-cell sequencing

Комментарии

  • @guitarsenpai420
    @guitarsenpai420 36 минут назад

    Horrors beyond our comprehension

  • @priyabhowmick3372
    @priyabhowmick3372 13 дней назад

    Very good

  • @kosheeka
    @kosheeka Месяц назад

    It is also the reason why researchers are turning to stem cell and primary cells to use alternative testing systems to see the drug effects on humans. It is much better than testing it on animals and produce consistent reproducible results in human tests as well.

  • @zilanayhan7864
    @zilanayhan7864 Месяц назад

    Nice explanation!

  • @Ahin_2001
    @Ahin_2001 Месяц назад

    Nice simulation, it's gives a clear picture of SPR and now I can imagine how it occurs😊

  • @deltapos-phanmemquanlybanhang
    @deltapos-phanmemquanlybanhang Месяц назад

    when we can purchase CAR-NK cells in Vietnam?

  • @irisattas284
    @irisattas284 2 месяца назад

    Great explanation. Thank you

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  • @WeirdBeardJay
    @WeirdBeardJay 3 месяца назад

    This will NOT end well.

  • @Duriel1000
    @Duriel1000 6 месяцев назад

    Why arent cell lines just referred to as "cancer"?

    • @rawdonwaller
      @rawdonwaller 3 месяца назад

      Because cell lines undergo apoptosis whereas cancerous cells are able to avoid apoptosis.

  • @rachelwilson8734
    @rachelwilson8734 6 месяцев назад

    Simulate a body on a chip? Sounds like a black mirror episode. No thanks.

    • @rob3433
      @rob3433 2 месяца назад

      Chips like this can potentially reduce the need for drugs trials in humans/animals or allow drugs to be more safely developed. If you’re worried about these organs undergoing pain, it could be possible to make ‘em without nerves that send pain signals.

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    🥵

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