- Видео 28
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Biomarkers of Aging Consortium
Германия
Добавлен 19 дек 2023
Establishing Reliable Biomarkers of Aging for Longevity Interventions.
Mahdi Moqri @ 2024 Biomarkers of Aging Conference
Executive Co-Director of the Consortium, Dr. Mahdi Moqri, provided a recap of the discussions from Day 1, which was intentionally not recorded. To foster open dialogue and the sharing of unpublished research, we ensured a confidential and collaborative environment by prohibiting recordings, promoting a more secure space for scientific exchange.
Timestamps:
[00:00:54] History of the Biomarkers of Aging Symposium and Conferences
[00:01:48] Day 1 Overview: Omics & Multi-Omics Biomarkers of Aging
[00:03:30] Day 1 Overview: Molecular, Digital & Physiological Biomarkers of Aging
[00:04:14] Day 1 Overview: Systems Aging
[00:05:30] Day 1 Overview: Longitudinal & Clinical Biomarkers
Dr. Mahdi Moqri is a...
Timestamps:
[00:00:54] History of the Biomarkers of Aging Symposium and Conferences
[00:01:48] Day 1 Overview: Omics & Multi-Omics Biomarkers of Aging
[00:03:30] Day 1 Overview: Molecular, Digital & Physiological Biomarkers of Aging
[00:04:14] Day 1 Overview: Systems Aging
[00:05:30] Day 1 Overview: Longitudinal & Clinical Biomarkers
Dr. Mahdi Moqri is a...
Просмотров: 29
Видео
Andrew Brack @ 2024 Biomarkers of Aging Conference
Просмотров 326 дней назад
Dr. Brack explains how ARPA-H, a U.S. research funding agency that supports transformative biomedical and health breakthroughs - ranging from the molecular to the societal - aims to deliver health solutions for all. He highlights programs such as the Biomarkers of Aging Consortium as key examples of this mission. Timestamps: [00:02:29] Intro ARPA-H and mission focus areas [00:05:58] Program and...
Lynne Cox @ 2024 Biomarkers of Aging Conference
Просмотров 126 дней назад
Lynne Cox introduces how Wellcome Leap builds bold, unconventional programs and funds them at scale. These programs aim to achieve breakthroughs in human health within 5-10 years, delivering seemingly impossible results on seemingly impossible timelines. She highlights Wellcome Leap's support for the clinical translation of biomarkers of aging - specifically biomarkers of resilience - through t...
John Earls @ 2024 Biomarkers of Aging Consortium
Просмотров 296 дней назад
Dr. John Earls explains how his research at the Buck Institute investigates the mechanisms of biological aging and the impact of healthy behaviors, using various biomarkers of aging as key indicators. Timestamps [00:00:07] Intro into John's path into aging R&D and the development of a biological age product and publication [00:01:07] Main findings of biological age estimate paper [00:03:48] How...
Eric Morgen @ 2024 Biomarkers of Aging Conference
Просмотров 46 дней назад
Eric Morgen presents how BioAge Labs is addressing metabolic diseases driven by the aging process by leveraging biomarkers of aging. He also shares updates on their leading clinical assets. Timestamps: [00:00:08] Biomarkers in aging clinical trials introduction [00:01:08] How BioAge Labs tackles metabolic diseases [00:03:15] Developing a pipeline of broad therapies, including Azelaprag harnessi...
Gordan Lauc @ 2024 Biomarkers of Aging Conference
Просмотров 556 дней назад
Gordan Lauc discusses the potential power of the human glycome to better understand and treat aging-related diseases and how IgG glycans are predictive biomarkers and modifiable functional effectors of age-related diseases. Timestamps [00:00:19] Glycans and their role in biology [00:02:12] Genos' role in glycan R&D and its application in aging biology [00:02:51] IgG gylcome composition is a bio...
David Furman @ 2024 Biomarkers of Aging Conference
Просмотров 606 дней назад
David Furman explains immunological biomarkers of aging and how inflammaging-the intersection of inflammation and aging-contributes to chronic disease. He highlights recent research progress and provides insights into how inflammaging influences disease development. Timestamps: [00:00:45] Immunological biomarkers of aging intro [00:01:03] How aging affects immune responses and cell phenotypes [...
Christin Glorioso @ 2024 Biomarkers of Aging Conference
Просмотров 246 дней назад
Christin Glorioso presents her work at NeuroAge Therapeutics, where she and her team address brain aging through a multi-modal, multi-omic approach powered by AI. Timestamps [00:00:42] Brain aging is a program that leads to neurodegenerative diseases that we can reprogram using drugs and lifestyle interventions [00:01:18] Epidemiology and biology of age-related neurodegenerative conditions [00:...
Gavin Zhou of Regenerative Bio @ 2024 Biomarkers of Aging Conference
Просмотров 66 дней назад
Gavin Zhou explores the Methylation-based Organ-Level Aging (MOLE) clock and its role in advancing organ-specific anti-aging therapies. Timestamps [00:01:27] Translation of biomarkers of aging: value and challenges [00:02:32] Regenerative Bio: building a closed research-industry loop for translational longevity [00:04:13] Regenerative Bio: two core platforms and three operational models [00:06:...
Xiao-Jun Ma @ 2024 Biomarkers of Aging Conference
Просмотров 56 дней назад
Xiao-Jun Ma highlights the innovative NULISA technology developed by Alamar Biosciences and its applications in key partnerships, including collaboration with the Biomarkers of Aging Consortium. Timestamps [00:00:40] NULISA: NUcleic acid-Linked Immuno-Sandwhich Assay: highly sensitive immunoassays for multiplexed protein detection [00:03:27] NULISAseq: Inflammation Panel 250: the most complete ...
Chiara Herzog @ 2024 Biomarkers of Aging Conference
Просмотров 96 дней назад
Chiara Herzog discusses clinical translation of biomarkers of aging, touching on her work in Austria and the work of the Biomarkers of Aging Consortium's Longevity Study, partnered with Harvard Medical School. Timestamps [00:00:47] Cardiovascular disease as a useful model for surrogate endpoint development for aging [00:01:25] Outstanding barriers for biomarkers of aging [00:03:06] Human interv...
Andrea Maier @ 2024 Biomarkers of Aging Conference
Просмотров 76 дней назад
Andrea Maier outlines a roadmap for precision geromedicine, offering insights into the community's current progress, future goals, and the steps needed to achieve them. Timestamps [00:00:29] Bringing precision gerotherapeutics to the clinic [00:01:10] Roadmap towards precision geromedicine [00:04:19] Health and lifespan and interest in healthy longevity medicine clinics [00:05:06] HELO (HEalthy...
Tina Woods @ 2024 Biomarkers of Aging Conference
Просмотров 56 дней назад
Tina Woods explores the human exposome, going beyond the biology of aging to promote extended healthspan, resilience, and flourishing. She also highlights the initiatives of the International Institute of Longevity. Timestamps [00:01:06] The Human Exposome Project: Vision and Mission [00:01:57] From Human Genome to Human Exposome Project [00:03:43] Exposome factors driving 80% of health outcome...
Flash Talks @ 2024 Biomarkers of Aging Conference
Просмотров 96 дней назад
Day 2 Flash Talks provided by the brilliant participating scientists from some of the world's best labs and companies. Timestamps in progress!
Jamie Justice @ 2024 Biomarkers of Aging Conference
Просмотров 56 дней назад
In this Day 2 mini-symposium, sponsored by our friends and partners at XPRIZE Healthspan, Jamie Justice explains how XPRIZE Healthspan is advancing the development of frameworks and biomarkers of aging for clinical trials. Thank you XPRIZE Healthspan for your support during this session! Timestamps: [00:00:44] Frameworks and Biomarkers of Aging for Clinical Trials: Session Intro [00:01:37] XPRI...