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REPROCELL
Великобритания
Добавлен 5 сен 2019
REPROCELL provide an integrated workflow with stem cells and discovery technologies for drug development and cutting-edge Regenerative Medicine. As a global technology partner, REPROCELL has the history, expertise and flexibility to accelerate your research.
Established in 2003 by preeminent Japanese university researchers, REPROCELL quickly became the leading stem cell research company in Japan. Soon thereafter, REPROCELL products were employed by Professor Shinya Yamanaka during his pioneering research on induced pluripotent stem cell technologies at Kyoto University. REPROCELL was also the first company to offer iPSC-derived human cardiomyocytes, hepatocytes and neuronal cells for research applications.
Across the entire organization, REPROCELL’s goal is the same; to better translate discoveries into therapies. Our global brands include: Stemgent, Biopta, Alvetex and BioServe.
Established in 2003 by preeminent Japanese university researchers, REPROCELL quickly became the leading stem cell research company in Japan. Soon thereafter, REPROCELL products were employed by Professor Shinya Yamanaka during his pioneering research on induced pluripotent stem cell technologies at Kyoto University. REPROCELL was also the first company to offer iPSC-derived human cardiomyocytes, hepatocytes and neuronal cells for research applications.
Across the entire organization, REPROCELL’s goal is the same; to better translate discoveries into therapies. Our global brands include: Stemgent, Biopta, Alvetex and BioServe.
Webinar: Modeling cardiac pathologies with TrueCardium™ | REPROCELL
Modeling cardiac pathologies with TrueCardium™: Engineered human tissue for drug discovery and cardiotoxicity screening
Generation of synthetic human tissue necessitates mimicry of native tissue cell composition, architecture, and molecular fidelity. Here, we detail the establishment of engineered iPSC-derived self-organized cardiac organoids (TrueCardium™ SCOs) comprising all cell types of native human cardiac tissue with its concordant molecular, metabolic, structural, and physiologic characteristics. SCO growth and maturation can be controlled and developmentally-staged to heart tissue from the linear heart stage to adult maturation. SCOs contain a lumen within the organoid core, envelo...
Generation of synthetic human tissue necessitates mimicry of native tissue cell composition, architecture, and molecular fidelity. Here, we detail the establishment of engineered iPSC-derived self-organized cardiac organoids (TrueCardium™ SCOs) comprising all cell types of native human cardiac tissue with its concordant molecular, metabolic, structural, and physiologic characteristics. SCO growth and maturation can be controlled and developmentally-staged to heart tissue from the linear heart stage to adult maturation. SCOs contain a lumen within the organoid core, envelo...
Просмотров: 209
Видео
Reproducible differentiation of ovarian support cells as a novel infertility treatment | REPROCELL
Просмотров 1612 месяца назад
Reproductive diseases impact at least 10% of the population, but limited research funding has reflected healthcare disparities and stalled innovation. The use of human induced pluripotent stem cells (hiPSCs) shows great promise in generating resourceful solutions for accelerating innovation in reproductive health. Recently, we demonstrated a novel approach for fast and efficient differentiation...
Biology Controlled: High quality iPSC-derived human cells for drug discovery therapy | REPROCELL
Просмотров 1,8 тыс.3 месяца назад
Pluripotent stem cells (PSC) are a promising source of in vitro-generated specialized cells for disease modeling, drug discovery, and cell therapy. However, large-scale cell differentiation is necessary to achieve this potential. Trailhead Biosystems utilizes the High-Dimensional Design of Experiments (HD-DoE™) platform to revolutionize the scientific discovery process in the field of developme...
Innovative Technology to Bioengineer Human Tissue | REPROCELL
Просмотров 1,1 тыс.5 месяцев назад
Tissues in the body are composed of different cell types that are highly organized in relation to each other. Often cells are arranged in distinct layers that enable signalling and cell-to-cell interactions. Recreation of these types of architecture will significantly evolve 3D cell culture to a new level where real tissue-like structures can be bioengineered in vitro for research and discovery...
Bringing Mesenchymal Stromal Cells into the Clinic| REPROCELL
Просмотров 6226 месяцев назад
Mesenchymal stromal cells (MSCs; also called Mesenchymal Stem Cells) are multipotent adult stem cells that have been defined and studied for several decades for their clinical potential. Indeed, these cells continue to be the source of numerous clinical trials, and interest in their use for therapeutic purposes continues to grow. Allogeneic MSCs are particularly interesting for their favorable ...
Inauguration of Beltsville GMP Facility| REPROCELL
Просмотров 917 месяцев назад
Highlights from the recent inauguration of the REPROCELL GMP Facility in Beltsville, MD. www.reprocell.com/ Follow us on LinkedIn: www.linkedin.com/company/REPROCELL Follow us on Twitter: REPROCELLglobal Browse our product catalog: www.reprocell.com/product-catalog Got a research project you are looking to outsource? Contact our scientists to arrange a free consultation: www.reproce...
Mature Chamber Specific Human Cardiomyocytes for High Throughput Cardiotoxicity Testing | REPROCELL
Просмотров 33411 месяцев назад
www.reprocell.com/ Follow us on LinkedIn: www.linkedin.com/company/REPROCELL Follow us on Twitter: REPROCELLglobal Browse our product catalog: www.reprocell.com/product-catalog Got a research project you are looking to outsource? Contact our scientists to arrange a free consultation: www.reprocell.com/contact
Production of Mesenchymal Stem Cells (MSCs) for Clinical and Research Projects
Просмотров 2,4 тыс.Год назад
The demand for Mesenchymal Stem Cells (MSCs) has risen significantly over the past two decades due to their established immunomodulatory and tissue regenerative activities. They show therapeutic potential in treating inflammatory diseases and stimulating tissue repair after injury, as well as a starting source for cell therapy and as a drug delivery vehicle. REPROCELL has developed a new collec...
Pharmacology-AI: Machine learning for precision medicine, made easy | REPROCELL
Просмотров 2,8 тыс.Год назад
Are you interested in harnessing the power of Precision Medicine for targeted treatment plans? Look no further! Introducing REPROCELL's groundbreaking technology, Pharmacology-AI. Precision Medicine is transforming healthcare by tailoring treatments to individual patients based on their unique genetic and clinical characteristics. However, analyzing large and complex patient data sets can be a ...
What is wire myography? | REPROCELL
Просмотров 675Год назад
www.reprocell.com/ Follow us on LinkedIn: www.linkedin.com/company/REPROCELL Follow us on Twitter: REPROCELLglobal Browse our product catalog: www.reprocell.com/product-catalog Got a research project you are looking to outsource? Contact our scientists to arrange a free consultation: www.reprocell.com/contact
Things to consider when searching for a supplier of cGMP iPSCs | REPROCELL
Просмотров 198Год назад
www.reprocell.com/ Follow us on LinkedIn: www.linkedin.com/company/REPROCELL Follow us on Twitter: REPROCELLglobal Browse our product catalog: www.reprocell.com/product-catalog Got a research project you are looking to outsource? Contact our scientists to arrange a free consultation: www.reprocell.com/contact
Customized Central Laboratory Services for Support of Global Clinical Trials: PBMC Processing
Просмотров 1 тыс.2 года назад
For more information visit our website: www.reprocell.com/ Central laboratory service (CLS) providers offer a range of operational capabilities to accelerate drug development programs and support global clinical trial needs. From routine peripheral blood mononuclear cell (PBMC) processing to more complex genomic, proteomic, and cellular analyses, CLS providers deliver consistent quality-control...
Bioreactor Culture of iPSC's with ABLE Biott | REPROCELL
Просмотров 1,3 тыс.2 года назад
Want to find out more about using ABLE Biott bioreactors for stem cell culture? www.reprocell.com/blog/how-to-mass-culture-induced-pluripotent-stem-cells-ipscs In 2006 Japanese researcher Shinya Yamanaka discovered 4 genes (now known as Yamanaka factors) that can revert somatic cells back into their pluripotent state. These induced pluripotent stem cells hold the potential to revolutionise the ...
Working with Mature, Chamber-Specific Cardiomyocytes | REPROCELL|
Просмотров 2602 года назад
www.reprocell.com/blog/ultimate-guide-stem-cell-services In this REPROCELL webinar Dr. Travis Block, joined by Dr. Andre Monteiro da Rocha present a new innovation in cardiomyocyte cell culture. Chamber-specific cardiomyocytes that can be matured on CELLvo™ Matrix Plus to achieve a new level of specificity and nuance in in vitro assays. Chamber specific cardiomyocytes faithfully recreate, in vi...
Tips for using Stemgent's hESC Cloning and Recovery Supplement | REPROCELL
Просмотров 802 года назад
Discover REPROCELL's Stemgent products www.reprocell.com/ This protocol video goes through the various steps involved in using Stemgent's hES cell cloning and recovery supplement and provides some useful tips for the process. Follow us on LinkedIn: www.linkedin.com/company/REPROCELL Follow us on Twitter: REPROCELLglobal Browse our product catalog: www.reprocell.com/product-catalog G...
Reconstituting Valproic Acid (VPA) for Reprogramming | REPROCELL
Просмотров 2962 года назад
Reconstituting Valproic Acid (VPA) for Reprogramming | REPROCELL
Passaging Human iPS Cells | REPROCELL
Просмотров 1,1 тыс.2 года назад
Passaging Human iPS Cells | REPROCELL
Using Small Molecules For Stem Cell Research | REPROCELL
Просмотров 1422 года назад
Using Small Molecules For Stem Cell Research | REPROCELL
Clinically compatible advances in blood-derived EPC isolation and reprogramming | REPROCELL Webinar
Просмотров 2403 года назад
Clinically compatible advances in blood-derived EPC isolation and reprogramming | REPROCELL Webinar
Enabling translational research through access to high quality biospecimens | REPROCELL
Просмотров 813 года назад
Enabling translational research through access to high quality biospecimens | REPROCELL
How to culture iPSCs in suspension without agitation | REPROCELL
Просмотров 2113 года назад
How to culture iPSCs in suspension without agitation | REPROCELL
What is Human Tissue Testing? | What in the Life-Sciences Podcast
Просмотров 8803 года назад
What is Human Tissue Testing? | What in the Life-Sciences Podcast
GMP Master Cell Bank Service | REPROCELL
Просмотров 1,6 тыс.3 года назад
GMP Master Cell Bank Service | REPROCELL
Novel Uses for PCR of iPSCs in Drug Discovery and Cell Biology | REPROCELL
Просмотров 4323 года назад
Novel Uses for PCR of iPSCs in Drug Discovery and Cell Biology | REPROCELL
REPROCELL clinical-grade stem cells | Consistency, safety, quality
Просмотров 1,1 тыс.3 года назад
REPROCELL clinical-grade stem cells | Consistency, safety, quality
BioEngineered Human Tissues for Skin, Cancer and Drug Metabolism | REPROCELL webinar series
Просмотров 2473 года назад
BioEngineered Human Tissues for Skin, Cancer and Drug Metabolism | REPROCELL webinar series
Providing testing solutions for the development of SARS-CoV-2 therapeutics | REPROCELL Webinars
Просмотров 513 года назад
Providing testing solutions for the development of SARS-CoV-2 therapeutics | REPROCELL Webinars
Review of Animal Derived Ancillary Materials for Research | REPROCELL
Просмотров 723 года назад
Review of Animal Derived Ancillary Materials for Research | REPROCELL
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This is very cool!
I have nerve damage
No commentary????
Can this platform be used to culture for 3 months? How long does the scaffold take to degrade?
何言ってるかわからん？字幕希望！
日本語か字幕お願いします
Read our protocol for culturing iPSCs using the ABLE Biott Bioreactor system on the REPROCELL website: www.reprocell.com/blog/how-to-mass-culture-induced-pluripotent-stem-cells-ipscs
Looking to isolate PBMCs from whole blood samples? Read our example protocol on the REPROCELL website: www.reprocell.com/blog/biopta/what-is-pbmc
Hi. I cultured the cells for one week following all instructions, however, when evaluated using SEM, I could not observe any cells, instead, I could see only the porous nature of the scaffold.
We're sorry to hear that. If you submit this message to the inquiry form on our website one of our technical team will be able to help. www.reprocell.com/contact You can also email info-emea@reprocell.com
Hi, does the ethanol have to be sterile/autoclaved before use?
According to Association for Professionals in Infection Control and Epidemiology (APIC), ethyl alcohol and isopropyl alcohol are not effective in sterilizing instruments because they lack sporicidal activity and can’t penetrate protein-rich materials. Isopropyl alcohol also lacks the ability to kill hydrophilic viruses. For these reasons, alcohol is classified as an intermediate level disinfectant. That is why we use autoclaves, gas sterilizers, hot beads, flames, chemicals or boiling water to properly sterilize the equipment. We use 70% and not higher percentages of ethanol, since 70% ethanol is better for disinfecting. It has more water, which helps it to dissolve more slowly, penetrate cells, and kill bacteria. Alcohol makes some bacteria and virus inactive because it lowers the water activity. Higher % Ethanol evaporates too quickly and is not effective when alcohol is lower than 70% is considered as 'too wet'. In cell culture we usually combine 70% ethanol and ultraviolet germicidal irradiation (UVGI) to sterilise surfaces, disposables, and microbiological safety cabinets.
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Interested work with reprocell
If you are interested in working with us, please use the contact form on our website: www.reprocell.com/contact
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Want to find out more about human tissue testing and it's uses? Find out more in our blog post "What is human tissue testing?": www.reprocell.com/blog/biopta/what-is-human-tissue-testing
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Let us know what you think of this amazing video!
Has the Alvetex scaffold benefited your research?
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Hey there! I would like to ask, for REPROCELL’s cell manufacturing service, are the MSCs grown in a closed or open system? Is there a page where I can look into how these cells are manufactured while establishing the cell bank? I’ve come across the Stemchymal AD-MSCs in my own research and am wondering how the cells were cultured for both the Taiwan and Japan clinical trials. A paper that I’ve come across in 2017 (Treatment of Spinocerebellar Ataxia with MSCs: A phase I/IIa Clinical Study) did not indicate the nature of how these cells were grown, whether if it was in a strict GMP suite and if the system was open or closed.
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What impact do animal derived products have on you?
Very helphul and informative! Thank you!
You're very welcome Fuyinh Shih! 🔬✨
何言ってるか全くわかりません。
Apologies cuouc - we are working on getting Japanese subtitles added to our videos. Please stay tuned over the upcoming months!