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@@Cycle-Tourer Hi, thanks for your question. This is quite specific, and I can only provide general advice. First, there are no known drug interactions between Diamox (acetazolamide) and Eliquis (apixaban), so that shouldn’t be an issue. However, DVT is a complex condition influenced by factors such as hypobaric hypoxia and endothelial dysfunction, both of which can increase the risk of thrombosis at high altitudes-even if your last thrombosis was 8 years ago. I would recommend continuing to take Eliquis as usual during high-altitude stays. However, I’m not aware of any recent studies on this topic. keep on pedaling.

​@@2bushes Thanks a lot. So that means, Generally, It possible to take Diamox (acetazolamide) to prevent AMS while taking an Eliquis (apixaban)? Or again: Not enough knowledge about this issue??? So basically as I understand you: Tendency to excessive clotting (that I have for sure, like my mother), with the high location - can increase the risk of second DVT, or even PE....

@@Cycle-Tourer Yes, I personally would take Eliquis and Diamox at the same time to reduce the symptoms of AMS if a slower altitude gain is not possible. Of course, a slow ascent is always better. Yes, the risk of blood clotting at high altitude is a bit higher. But there are many factors to consider, like dehydration, fatigue, or maybe a recent long-distance flight.

@@2bushes THANKS. You helped me a lot.

Es gibt mehrere Busse aus Kathmandu. Sie starten in Sorhakhutte, das einem Busbahnhof ähnelt - eine Straße bzw. ein Stadtteil, in dem einfach viele Busse parken. Man muss einfach direkt dorthin gehen und ein Ticket bei einem beliebten Unternehmen am Vortag kaufen. Ich habe mir notiert, dass es 900 NPR pro Person kosten soll. Was wir letztendlich bezahlt haben, kann ich mich leider nicht mehr erinnern. Die Busse heißen alle "Deluxe Tourist Bus" oder ähnlich und versprechen Klimaanlage und bequeme Sitze - da sollte man skeptisch sein und einfach einen Bus erwarten, der einen nach Pokhara bringt. Die Reise ist lang, bis zu 9 Stunden, teilweise weil die Straßen so schlecht sind. Unser Bus hat auch einmal für eine Mittagspause bei einer Art Kantine angehalten - es ist gut zu wissen, dass das stattfinden wird, weil wir das irgendwie nicht gecheckt haben, zu spät dran waren und uns dann ultra-beeilen mussten. Das war aber vor fast 3 Jahren - es mag sein, dass sich einiges geändert hat.

Thanks! Do you plan visiting Armenia yourself?

Oh yeah, we wish to and miss Jimmy too. The whole Atlantic Ocean is in-between us :(

I believe we only had 2 bottles each on our bikes. Water is not a big concert on the circuit, first of all because you eat at the tea houses, second of all because there are little shops every now and then selling drinks (especially in the lower parts of the circuit) and thirdly because there is plenty of waterfalls and rivers. We just drank from them when we needed and had our charcoal filtering system with us in case but i think we did not use it. We felt ok afterward but please check twice if drinking this water is safe - we assumed it is. I recommend drinking sweet drinks (like cola) in the upper parts. you really do need this sugar boost 😉

Thank you, you are too kind 😊

Hello Kevin, we were talking about you lateöy and apparently brought you with our thoughts! We need to catch up on whats new with you! <3

Hi, honestly, we didn't know about the permits and restrictions until a guide told us at the end of our stay. We came to Nepal the first possibility after the coronavirus pandemic - there were almost no tourists and locals (also guides!) didn't seem to bother at all. For now, I would recommend trying to organise a licence through a travel agency - I doubt the Nepali paperwork is doable for foreigners.

ok thank you very much @@2bushes

Hey, that's a tough one! 1. Definitely take shoes with a good profile, there are sections that require a good grip 2. You'll be crossing rivers and going through a lot of muddy sections - the more waterproof the better 3. Depending on where you start, "proper" walking boots might be too warm - around Pokhara you'll have 25 degrees Celsius and easy terrain 4. Jakob had waterproof click shoes from Shimano with a GOA system for cross-country and I took my above-the-ankle Merells with lightweight (soft) soles. Both worked great. I do not think there is much "advantage" in taking click shoes or above-the-ankle shoes - I would simply take the ones that are most comfortable :) Our friend Jimmy walked in sandals! I hope this helps!

:D Die scheinen auch echt erfolgreich zu sein!

good luck!!!

We keep our fingers crossed for your friend! <3

We went there in November, generally speaking, late Autumn or spring are the best seasons to visit Annapurna Circuit, because of less risk of a landslide. I recommend you to join one of the many Nepali travel groups and ask for the current weather conditions :)

It really is!😮

Thank you! Nice to hear it from a Nepali <3

well i guess we’ll have to start now 😂

@@2bushes lol glad he got his way

Haha, good point! Well in the USA the bear boxes are placed everywhere where bears are, even at free campsites (this video was made in one). You can also store your food in a bear container (impractical for a bike) or hang it on a tree (which we did sometimes, but it is quite hard and we are not pros in this technique so we did not include it)

Oh, I know 😩 I eat in McDonalds often now, and I find their food not as calorie-rich as I need. Who would have though, huh? But during the long winter I hope to put on some weight again.

These two are elite athletes. Riding bike 80 miles (off road) with +5-6k feet of Elevation gain Daily! It’s Impossible to consume enough calories, you’ll almost aways be in a calorie deficit. It happens to everyone that pushes their body to the extreme.

That’s true! Calorie intake can be a challenge. Especially over such a long cross country ride.

We consider your comment a great compliment! No, all our gear was on our bikes that we rode, pushed and eventually carried up and the bikes weight somewhere between 20 and 25kg. But there is bunch more people who did that, we are not the first! ;)

@@2bushes In which case, quite an achievement. I was basing my comment on a couple of observations: you appeared not to be alone (pics from the air?) and your loads looked very small - no panniers. I can't imagine doing the trek with less than a 30-litre pack even without bike tools, spare tubes, etc., which seems more than you were carrying. I did the Everest trek back in '86 and have thought about what would be possible on a bike. Apart from the daunting logistics of ascending stone steps and avoiding precipices, I suspect going by bike creates a kind of mental barrier between a rider and those one encounters along the way, especially locals who are always on foot. On a bike, you're not, in my view, travelling in the spirit of those to whom these pathways truly belong. But neither is peak-bagging, which doesn't seem to be in conflict with local cultures.

@@briandriscoll1480 oh well, my husband is quite good in flying the drone - he can ride the bike and fly in the same time, which is quite awesome. And yes, we travel very light - currently on the road since 2,5 Months in the USA with similiar volume. As you know after compleating the EBC - you do not have to carry much - the food and lodging are provided, so there is no neet to carry a tent or a stove. Our friend hiked the Annapurna Circuit without a sleeping bag! Anyway, if you decide to bike the EBC, let us know! You might be the first one to do that!

@@2bushes At age 67, I don't think I'll be doing that one, unless I can do it with an eMTB. I'm actually quite curious about how little one need pack on major treks like Annapurna circuit. No tent, of course, but it can be dicey to be caught out in freezing temps or monsoon rains without adequate gear. And a medical kit is mandatory. Do you have an idea how many litres/cubic inches and kilos/pounds you were each toting?

@@briandriscoll1480 I assume 10kg each excluding water and snacks. The winter gear is surprisingly light. We both had an ultralight sleeping bag for 0 Celcius, a liner, a down jacket (bought in Kathmandu), 3 merino shirts, 2 bike jackets (for different temperatures and the second one waterproof), hiking shoes and 2 pairs of cycling pants. My husband is a doctor, so of course, we had a first aid kit and emergency high altitude meds as well. 2 spare tubes each + tools and some cosmetic products + filming gear (mini drone, go pro, 2 x iphone, spare battery and a mic). That's it :) Charging eMTB might be tricky but I keep my fingers crossed!!!

thanks, we are glad you enjoyed it! AMS and it's prevention is fascinating!

Better now, than later! The treck is not filled with tourists due to covid as it normally would be. If you need help with planing let us know! 😌

@@2bushes How many kilometers did you do per day? I am thinking to do all nepal trails :| on my touring mtb, also how expensive are the hotels and stuff.

@@egonzalez4294 Wow, we keep our fingers crossed! :) The first four days we did roughly 50km/day, then an acclimatisation day in Manang and after that: Manang-Yak Kharka, Yak-Kharka-High Camp, High Camp - Thorung La - Muktinath. We didn't do many km per day for two reasons: the road is quite challenging (lots of hike-a-bikes and steep climbs) and we were sticking to the rule of max. 500am above 3k. I must admit I don't remember what the hotels cost, I believe it was around 2000-3000 rupees per person per dinner(as we explained the accommodation was free if you paid for your meals) and around 900 for breakfast.

we are very happy that our video evoked these nice memories! <3

Hello again! :D Do you also wish to come back to Nepal as much as we do?

<3