Osteosarcoma: MIB Agents Osteosarcoma Alliance
Osteosarcoma: MIB Agents Osteosarcoma Alliance
  • Видео 333
  • Просмотров 318 506
Live-cell whole-tissue models to study dynamic tumor-microenvironment signaling cross-talk
Osteosarcoma Webinar Series: Alexander Davies, DVM, PhD joins us on OsteoBites to discuss his work which is focused on dynamic tumor-microenvironment signaling cross-talk, signal integration, and the development of 3D organotypic and tissue models to study these interactions using live-cell microscopy techniques.
Results from studies in the Davies Lab demonstrate the utility of a novel dynamic live-cell tissue model, the lungSITE model, to quantitatively measure and understand tumor signaling dynamics and behaviors within the context of the lung metastatic niche. Data obtained from this model provided new insights into how spatial position and temporal response influence signaling dynamics...
Просмотров: 86

Видео

osTEAo: Cancer Fatigue How to Escape the Cancerverse
Просмотров 6621 день назад
Join hosts Mia and Sammy on the latest episode of osTEAo, where they dive deep into the challenges of navigating life with cancer fatigue. In "Cancer Fatigue: How to Escape the Cancerverse," they are joined by OsteoWarriors Sloane and Matthew to explore the emotional and physical toll of living in the "Cancerverse" and to share personal stories of how they find moments of normalcy amidst the ch...
COG Blueprint for Research on Bone Tumors
Просмотров 8521 день назад
Dr. Damon Reed joins us on OsteoBites to discuss the vision for research on bone tumors from the Children's Oncology Group (COG) Bone Tumor Committee. Damon Reed, MD is the inaugural Head of the Division of Pediatric Solid Tumors and Chief of the Pediatric Sarcoma Service at Memorial Sloan Kettering Cancer Center. Dr. Reed founded the Sunshine Project, the Pediatric Cancer Foundation’s pediatri...
Penelope, Sammy & Kara
Просмотров 60Месяц назад
These three Junior Advisory Board members share a conversation. What it is about, you will have to click for. Most of all, Penelope - we will always remember you with love. You used your life for good; you Made It Better.
A Message from Kara
Просмотров 74Месяц назад
Kara shares her osteosarcoma story of hope and the one word she uses to describe MIB Agents.
OsteoWarrior Sammy
Просмотров 125Месяц назад
Sammy shares her osteosarcoma story of hope and shares what you can do to help MIB Agents.
Understanding Tumor Evolution in Osteosarcoma
Просмотров 145Месяц назад
Osteosarcoma Webinar Series: Chelsey Burke, MD, a physician-scientist from Memorial Sloan Kettering Cancer Center and an OutSmarting Osteosarcoma Young Investigator 2024 grant recipient, shares findings from her work studying the evolution of osteosarcoma tumors. At present, we have a limited understanding of how osteosarcoma tumors change with conventional treatment and go on to develop drug r...
Macrophage engineered vesicles to treat pediatric Osteosarcoma.
Просмотров 83Месяц назад
One of our MIB Agents OutSmarting Osteosarcoma 2024 grant recipients, Dr. Chris Richards, an Associate Professor from the University of Kentucky provides an overview of his funded work on macrophage engineered vesicles to treat pediatric osteosarcoma. This presentation focuses on the development of nanoscale vesicles derived from immune cells that can be utilized as immunomodulatory and therape...
Penelope
Просмотров 2792 месяца назад
This Giving Tuesday, we are grieving the loss of Penelope. We need your support to keep MIB Agents' Programs, Education, and Research going, #BecauseOfPenelope.
osTEAo: Hospital Holidays
Просмотров 762 месяца назад
An osteosarcoma diagnosis translates to lots of time in the hospital and an unpredictable schedule that is driven by treatment plans and unexpected complications. Spending holidays and important days in the hospital can be particularly rough. OsteoWarriors Sammy, MacKenzie, and Matthew share their hospital holiday experiences, bad and good, from nausea ruining a pumpkin pie to breaking out of t...
Repurposing Virus Specific T cells as Immune Therapy for Osteosarcoma
Просмотров 1222 месяца назад
One of our MIB Agents OutSmarting Osteosarcoma Young Investigator 2024 grant recipients, Arianexys Aquino-López, MD, PhD, a physician-scientist from Texas Children's Hospital/Baylor College of Medicine provides an overview of her funded work on Repurposing Virus Specific T cells as Immune Therapy for Osteosarcoma. In this presentation, she discusses repurposing virus-specific T cells so that th...
Repurposing Drugs for Osteosarcoma
Просмотров 2083 месяца назад
Osteosarcoma Webinar Series: Osteosarcoma Webinar Series: One of our MIB Agents OutSmarting Osteosarcoma 2024 grant recipients, Dr. Shahana Mahajan, a Professor and Principal Investigator from Hunter College of the City University of New York will provide an overview of her funded work on repurposing drugs for metastatic osteosarcoma. Dr. Mahajan will share the recent findings from her lab on t...
The ablative and immunomodulatory effects of histotripsy treatment in osteosarcoma
Просмотров 1363 месяца назад
Joanne Tuohy, DVM, PhD from Virginia Tech and the Virgina-Maryland College of Veterinary Medicine will be sharing information about canine trials studying histotripsy as a novel tumor ablation modality for treating osteosarcoma. Histotripsy is a focused ultrasound tumor ablation technique that is non-invasive, non-ionizing and non-thermal, and it also has potential to induce immunomodulatory ef...
osTEAo: Spooky Sarcoma Stories
Просмотров 8473 месяца назад
Get in the Halloween spirit with OsteoWarriors Mia, Sammy, Gillian, MacKenzie, and Matthew who share spooky stories from their osteosarcoma treatment experiences. Find out why being diagnosed with osteosarcoma is like entering the Twilight Zone where things may seem normal, but weird and random things lurk. Hallucinations, disorientation, and delirium can be common side effects from pain and su...
Molecular and cellular deconstruction of metastatic osteosarcoma
Просмотров 1374 месяца назад
Dr. Troy McEachron joined us on OsteoBites to discuss the molecular and cellular deconstruction of metastatic osteosarcoma. Immunotherapy holds great promise for a subset of patients whose tumors respond to this innovative and remarkable approach. The therapeutic benefit for patients with osteosarcoma has been largely underwhelming, prompting clinical, translational, and basic scientists to ask...
osTEAo: Back to School: Cancer + Curriculum
Просмотров 3,4 тыс.4 месяца назад
osTEAo: Back to School: Cancer Curriculum
Penelope - Bows
Просмотров 444 месяца назад
Penelope - Bows
OutSmarting Osteosarcoma 2025 Overview
Просмотров 755 месяцев назад
OutSmarting Osteosarcoma 2025 Overview
Fit for Filing Academic Clinical Trials: An Industry Perspective
Просмотров 985 месяцев назад
Fit for Filing Academic Clinical Trials: An Industry Perspective
High Intensity Focused Ultrasound (HIFU) For Palliation of Canine Appendicular Osteosarcoma
Просмотров 2915 месяцев назад
High Intensity Focused Ultrasound (HIFU) For Palliation of Canine Appendicular Osteosarcoma
osTEAo - Clear Scans…So Now What?
Просмотров 4445 месяцев назад
osTEAo - Clear Scans…So Now What?
Clinical Utility of Functional Precision Medicine to Guide Treatments for Osteosarcoma Patients
Просмотров 1325 месяцев назад
Clinical Utility of Functional Precision Medicine to Guide Treatments for Osteosarcoma Patients
FACTOR 2024 Highlights
Просмотров 1875 месяцев назад
FACTOR 2024 Highlights
Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy
Просмотров 1876 месяцев назад
Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy
A Multi-Institution Study in Combination with Relapsed or Refractory Pediatric Bone and Soft Tissue
Просмотров 1866 месяцев назад
A Multi-Institution Study in Combination with Relapsed or Refractory Pediatric Bone and Soft Tissue
osTEAo: The Sibling Situation
Просмотров 2,9 тыс.6 месяцев назад
osTEAo: The Sibling Situation
Genomes, Avatars and AI: The Future of Personalized Medicine
Просмотров 1226 месяцев назад
Genomes, Avatars and AI: The Future of Personalized Medicine
Exploring Novel Immunotherapies for Canine Osteosarcoma
Просмотров 4838 месяцев назад
Exploring Novel Immunotherapies for Canine Osteosarcoma
Learn more about MIB Agents
Просмотров 1088 месяцев назад
Learn more about MIB Agents
A Guide to the FACTOR 2024 Scientific Panels with Matteo Trucco, MD
Просмотров 3138 месяцев назад
A Guide to the FACTOR 2024 Scientific Panels with Matteo Trucco, MD

Комментарии

  • @eeroala5132
    @eeroala5132 20 дней назад

    Thank you for posting these!

    • @osteosarcomaMIB
      @osteosarcomaMIB 19 дней назад

      @@eeroala5132 thank you for watching and subscribing.

  • @jaimintadvi1530
    @jaimintadvi1530 25 дней назад

    I am going to second lung surgery second time relapse in lung

    • @osteosarcomaMIB
      @osteosarcomaMIB 25 дней назад

      @Jaimintadvi, sad to read this, and we are with you.

  • @UghVICTOR
    @UghVICTOR Месяц назад

    So powerful 💕💕 love what Sammy and everyone at MIB have done Love moms

    • @osteosarcomaMIB
      @osteosarcomaMIB Месяц назад

      Thank you for being an Agent and Making it Better @UghVICTOR :)

  • @lindakennington5267
    @lindakennington5267 2 месяца назад

    Penelope was sweet, feisty and independent. Grateful for the time I was able to spend with her. I will always remember her.

    • @osteosarcomaMIB
      @osteosarcomaMIB 2 месяца назад

      @@lindakennington5267 that she was! How sorry we are for the loss of her from your life. Our sympathy 🫶.

  • @Caydoen
    @Caydoen 2 месяца назад

    Je moeder is lekker zonder haar en heel erg zappig

  • @Caydoen
    @Caydoen 2 месяца назад

    L gepakt je moeder

  • @inesalnesa4438
    @inesalnesa4438 3 месяца назад

    Christina hello. My son has been sick with osteosarcoma since 2018 . Multiple metastases in the lungs and soft tissues of the thigh. Can I ask the doctor a question? Can my son take riluzole?

  • @kitkatcrackalac
    @kitkatcrackalac 3 месяца назад

    So proud of y’all! Thank you for sharing this!

    • @osteosarcomaMIB
      @osteosarcomaMIB 3 месяца назад

      Thank you @Kitkatcrackalac! We appreciate you right back :)!

  • @assmabahalddin5694
    @assmabahalddin5694 5 месяцев назад

    Can we use bevacizumab with atezolizumab instead of cabozantinib?

    • @osteosarcomaMIB
      @osteosarcomaMIB 5 месяцев назад

      As we do not have scientific expertise, we suggest you inquire with the clinical trial principal investigator, Andy Livingston, MD at MD Anderson Cancer Center. His contact info can be found on the clinical trial page. Best wishes: www.cancer.gov/research/participate/clinical-trials-search/v?id=NCI-2021-06970

  • @carriganmnelson
    @carriganmnelson 6 месяцев назад

    😍😍😍

  • @jmedina7877
    @jmedina7877 6 месяцев назад

    This so beautiful 🫶🏼🎗️🌻

  • @eeroala5132
    @eeroala5132 6 месяцев назад

    Good question about collecting T cells preemptively to get better quality.

  • @mark6173
    @mark6173 6 месяцев назад

    Lost my 14-year-old son to bone cancer it's just not fare 💔😭😭

    • @osteosarcomaMIB
      @osteosarcomaMIB 6 месяцев назад

      How sorry we are to read this. We have to do better, because of your son and too many kids and young adults who lost their lives to cancer. We have a bereaved parent community and programs with and by people who truly understand. If we can be helpful, please let us know.

  • @ericklawun7768
    @ericklawun7768 6 месяцев назад

    Thx for sharing. Just got my atk leg and this helps

  • @samgregory762
    @samgregory762 6 месяцев назад

    Hey Mia! I know someone name Mia she’s also pretty cool!

  • @danielatapia7243
    @danielatapia7243 6 месяцев назад

    May there be a treatment soon! enough amputations! I have been surviving osteosarcoma. I am a fighter 💛

  • @MorganJunglin
    @MorganJunglin 6 месяцев назад

    Because of me

  • @eeroala5132
    @eeroala5132 7 месяцев назад

    Thank you for making these videos. I was wondering why Mirfamurtide was not approved in the United States, thank you for explaining the reason.

    • @osteosarcomaMIB
      @osteosarcomaMIB 7 месяцев назад

      As of August 2007, the U.S. Food and Drug Administration (FDA) has not approved mifamurtide, also known as L-MTP-PE or Mepact, for the treatment of non-metastatic osteosarcoma in children and adolescents. The FDA cited concerns about the study design and analysis as the reason for the rejection. However, mifamurtide is available for clinical use in other countries, including Europe, Mexico, South Korea, Switzerland, and Israel.

  • @eeroala5132
    @eeroala5132 7 месяцев назад

    Great presentation. I am looking forward to the results from this trial and if it can leverage the abscopal effect of cryoablation.

  • @Amore595
    @Amore595 7 месяцев назад

    Thank you. You help me so much 🌞

  • @eeroala5132
    @eeroala5132 8 месяцев назад

    Cryoablation seems to have significant benifit that were not initially apparent. It may be a key to controlling metastasize in the lungs.

  • @TheAccidentalGangster
    @TheAccidentalGangster 8 месяцев назад

    I love to interview you on my show Stories with Ori

  • @TheAccidentalGangster
    @TheAccidentalGangster 8 месяцев назад

    You’re an amazing strong young lady. Keep it moving

  • @beccanance7454
    @beccanance7454 8 месяцев назад

    Yall are so amazing - thank you for sharing your experiences!! And thank you MIB Agents for supporting this incredible cause <3

    • @osteosarcomaMIB
      @osteosarcomaMIB 8 месяцев назад

      Hi @BeccaNance, thank you for your very kind words. Your appreciation and encouragement are so important to us :).

  • @shickman1561
    @shickman1561 8 месяцев назад

    Why do no organizations help kids after treatment?

    • @osteosarcomaMIB
      @osteosarcomaMIB 8 месяцев назад

      We do indeed help after treatment 💛. Is there someway we can help you?

  • @eeroala5132
    @eeroala5132 8 месяцев назад

    Cryoablation for lung mets is very intriguing.

  • @donreinke5863
    @donreinke5863 8 месяцев назад

    Although I am long past the age that I would develop this type of cancer, I cant imagine what it would be like to be young knowing that despite the fact you had a limb amputated to stop it, its likely to return with a vengeance,

  • @eeroala5132
    @eeroala5132 9 месяцев назад

    Did the cryoablation cause any reduction in lung function? Or any perceived reduction in lung function?

    • @osteosarcomaMIB
      @osteosarcomaMIB 9 месяцев назад

      Hi! My interventional radiologist preserves as much healthy tissue as possible, and I feel like I have full lung function. I’ve had over 30 lung ablations and my only noticeable long-term effects are more frequent hiccups and some ab cramping from minimal nerve damage from repeated local anesthesia. - Mia

  • @brianbrooks3908
    @brianbrooks3908 9 месяцев назад

    This is awesome! I’m a 39 year survivor. I longed for connections like this back in the day when I was a patient. I’m so proud of all you😎

    • @osteosarcomaMIB
      @osteosarcomaMIB 9 месяцев назад

      We wish you did too! Congratulations on being a long-term survivor! You give us all hope!

  • @osteosarcomaMIB
    @osteosarcomaMIB 9 месяцев назад

    Please donate HERE: give-usa.keela.co/2024-mib-agents-day-of-giving and SHARE! We need YOUR help to Make It Better!

  • @glennquagmire34
    @glennquagmire34 9 месяцев назад

    RIP collin.

  • @mark6173
    @mark6173 10 месяцев назад

    Will we ever find a cure for this disease? My son has been gone 5 years now also need a cure for a broken heart 💔

    • @osteosarcomaMIB
      @osteosarcomaMIB 10 месяцев назад

      How sorry we are for the loss of your son to this disease. We are working on it with everything we have. We would be honored to have his name on our list of OsteoAngels that we honor and remember regularly and especially on the first Sunday of each month. We also have Healing Hearts for bereaved OsteoParents. You are most welcome.

    • @mark6173
      @mark6173 10 месяцев назад

      Thank you his name is Zack 🧡

    • @osteosarcomaMIB
      @osteosarcomaMIB 10 месяцев назад

      @@mark6173 To add Kyle, would you add him to the link below. We are honored to have him to the list of those OsteoWarriors and Angels whose names are spoken, prayed for, and honored regularly. www.mibagents.org/agents/prayer-agents

    • @mark6173
      @mark6173 10 месяцев назад

      @osteosarcomaMIB Sorry, his name is Zack not Kyle

  • @venomvandal5443
    @venomvandal5443 10 месяцев назад

    I love you guys.

  • @countmein8448
    @countmein8448 10 месяцев назад

    Thank you! 💛

  • @Bibijanstar
    @Bibijanstar 11 месяцев назад

    no problem ALLAH has given you cuteness and beauti

  • @solarsage252
    @solarsage252 Год назад

    I am 29 chapters into my novel, I don't expect to be famous or have it sell ridiculously or anything like that. But if it did that would be nice, point is all of the money I make from it will be donated to you. 15 years, one month and 21 days of absolute hopelessness and despair. All that time wishing it was me and not her, you people are severely underrated and need more support. It kills more than children, it killed my soul. I wish I could have helped her, it won't bring her back but maybe if i can contribute somehow in the future..... Maybe someone else won't have to live in a nightmare.

  • @mayafinjadinig7895
    @mayafinjadinig7895 Год назад

    thank you so much!

  • @internalbattle
    @internalbattle Год назад

    Sending hugs. Devestating disease 💛

  • @alvarocastrocid2186
    @alvarocastrocid2186 Год назад

    Thank you so much for putting this great information out!

    • @osteosarcomaMIB
      @osteosarcomaMIB Год назад

      Thank you for listening. Be sure and check out the 100+ addition OsteoBites episodes as well as our Young Adult podcast, osTEAo.

  • @JahoSelamaj
    @JahoSelamaj Год назад

    God bless her

  • @jaimintadvi1530
    @jaimintadvi1530 Год назад

    Is immunotherapy working in osteosarcoma??

  • @regularguysmokingfood
    @regularguysmokingfood Год назад

    Thanks for sharing your story Carey. You are a real inspiration especially for those of us who struggle with a chronic illness or any serious illness for that matter. God bless and take care

  • @jaimintadvi1530
    @jaimintadvi1530 Год назад

    Is i take immunotherapy for osteosarcoma metastatic??

  • @jaimintadvi1530
    @jaimintadvi1530 Год назад

    Second time i have detected osteosarcoma in lungs should i survive??

    • @osteosarcomaMIB
      @osteosarcomaMIB Год назад

      Hello - How sorry we are that you have this news. Yes, there is hope, always. Please see our website (MIBagents.org) and look for the page "Stories of Hope." There are many who have faced a relapse and are alive and well. Wishing you all the best.

    • @gordanazakula5669
      @gordanazakula5669 9 месяцев назад

      Beautiful girl!!! I would NEVER consent to amputation and chemo. For me, no quality of life!!! Please reply to me.​@osteosarcomaMIB

  • @rodvb1
    @rodvb1 Год назад

    Id love if you can fin different perspectives on the decission process, and the different things you have to face with each different decission. I've heard of cases when they choose amputation rather than limb salvage but they dont explain all the things they took into account to make that decission. I had LSS 13 years ago and despite the first year was very rough i had very good results and a very functional leg. Except ive had pain crisis from time to time. Now my prosthesis is becoming quite loosen and i may have to face revision surgery in the near future anf the thought of dealing with all of that again makes me wanna rethink my options. And despite ive had so many good years the fact that these are not permanent surgeries and that ill have to pay to go through all of that once again is really scary. Idont know id just like to listen to more perspectives on that subject.

    • @osteosarcomaMIB
      @osteosarcomaMIB Год назад

      This is something near and dear to all of us OsteoWarriors. Great suggestion! Will share with the osTEAo hosts for their consideration and discussion of how best to deal with these decisions.

    • @osteosarcomaMIB
      @osteosarcomaMIB Год назад

      Also, check out OsteoBites where there are several episodes where LSS, Amputation, and Rotationplasty are discussed with both the surgeon and the patient as guest speakers.

  • @kelliaholzworth9815
    @kelliaholzworth9815 Год назад

    Wow, she was really great at explaining the immune response. I love the clone trooper analogy!

  • @jeffreyc.walkeriii8231
    @jeffreyc.walkeriii8231 Год назад

    Thank you Kara. I am picking up my Prosthetic (below the right knee) the day after tomorrow. Wish me LUCK! :-)

    • @osteosarcomaMIB
      @osteosarcomaMIB Год назад

      May good luck be with you - though we suspect you do not need luck, you have already been through what most people believe to be their worst nightmare - and yet, you are smiling, alive, hopeful. Hope all is well with you and your new leg!

  • @patriceg8456
    @patriceg8456 Год назад

    We had the same experience when my 17yo was diagnosed. I am still grappling with some of those relationships and trying not to be resentful

    • @osteosarcomaMIB
      @osteosarcomaMIB Год назад

      @patriceg8456 how sorry we are that you experienced the same pain. Two thoughts for you: 1. Those that "left" were likely not your people to begin with. A painful loss - yes. Are you better off in the long run knowing that they are not meant for you - yes. 2. All above being written - can you remember a time when you did not have the courage, ability, knowledge, empathy, or bandwith, to show up for someone who was suffering that you knew? I know many of us have missed that opportunity to show love when we could have/should have. Give grace, and grace shall be yours. Hoping your 17 yo is well!

  • @elisecroissant
    @elisecroissant Год назад

    This is amazing, thank you guys so much

  • @raghavkumar6074
    @raghavkumar6074 Год назад

    Same here bro thanks for your inspiration.❤