GARDP
GARDP
  • Видео 160
  • Просмотров 202 382
Progressing an antibacterial drug discovery project - an SME perspective
Speakers:
- Alisa Serio, Executive Director of Microbiology and Nonclinical Development, Paratek Pharmaceuticals (USA)
- Victoria Savage, Chief Scientific Officer, INFEX Therapeutics Ltd (UK)
Moderator: Daniel Ritz, Senior Director - Senior Group Leader Biology Technologies / Lead Discovery, Idorsia Pharmaceuticals Ltd. (Switzerland)
Schedule:
0:00 Webinar opening words
03:50 Presentation 1: Progression criteria and go/no go decisions in antibacterial drug discovery - a perspective from Paratek Pharma (Alisa Serio)
28:12 Presentation 2: Progressing an antibacterial drug discovery program - a perspective from INFEX Therapeutics (Victoria Savage)
50:14 Questions & Answers
GARDP: www.gardp.org/
REVI...
Просмотров: 154

Видео

Efflux inhibitors: A strategy to tackle multidrug resistance
Просмотров 3482 месяца назад
Speakers: - Helen Zgurskaya, George Lynn Cross Professor, University of Oklahoma (USA) - Ruben Hartkoorn, Director of Research, Institut Pasteur de Lille (France) - Timothy Opperman, Senior Research Scientist, Microbiotix (USA) Moderator: Laura Piddock, Scientific Director, GARDP (Switzerland) Schedule: 0:00 Webinar opening words 03:29 Presentation 1: Deciphering antibiotic resistance: Efflux p...
Progressing a discovery project - Criteria and challenges
Просмотров 2553 месяца назад
REVIVE webinar, broadcast on 09 February 2024. Speakers: - Kenneth (Ken) Bradley, Global Head, Infectious Disease Discovery, Roche (Switzerland) - Diarmaid Hughes, Professor of Medical Molecular Bacteriology, Uppsala University (Sweden) Moderator: Karen Bush, Professor of Practice in Biotechnology, Emerita, Indiana University (USA) Schedule: 0:00 Webinar opening words 03:12 Presentation 1: Prog...
Difficult-to-treat resistance (DTR)
Просмотров 1203 месяца назад
Difficult-to-treat resistance (DTR) Gavin Barlow, Hull York Medical School (UK) Read the definitions on the REVIVE Antimicrobial Encyclopaedia here: revive.gardp.org/resource/difficult-to-treat-resistance-dtr/?cf=encyclopaedia
What does the future look like if pull incentives to support antibiotic R&D are insufficient?
Просмотров 1234 месяца назад
AMR Discussion webinar, broadcast on 27 February 2024: This webinar discusses potential solutions, including support for non-profit R&D organizations, to get new treatments to patients in the scenario of inadequate investment in industry R&D i.e., few or no additional ‘pull’ investments, or ‘pull incentives’ that do not meet industry expectations as to the size of the reward. It examines the be...
SECURE: Improving access to antibiotics through new economic models
Просмотров 1675 месяцев назад
GARDP Webinar co-hosted with WHO, broadcast on 14 February 2024 Speakers: - Kim Faure, Project Lead for SECURE - Alexandra Cameron, Senior Expert in the WHO’s AMR Division - Yewande Alimi, AMR and One Health Unit Lead at the Africa CDC - Joël Denis, Director General of Canada’s Antimicrobial Resistance Task Force at the Public Health Agency of Canada. Moderation by Javier Guzman, Director of Gl...
What do the various non-commercial actors in the antibiotic R&D ecosystem do?
Просмотров 1915 месяцев назад
REVIVE webinar, broadcast on 22 January 2024. Speakers: - Laura Marin, Head, Joint Programming Initiative on Antimicrobial Resistance - JPIAMR (Sweden) - Erin Duffy, Chief of R&D, Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator - CARB-X (USA) - Peter Beyer, Deputy Executive Director, Global Antibiotic Research & Development Partnership - GARDP (Switzerland) Moderator: - He...
Putting public health needs at the centre of antibiotic drug development
Просмотров 2516 месяцев назад
GARDP develops new antibiotic treatments for drug-resistant bacterial infections that pose the greatest threat to human health, and makes them accessible to the people who need them. By focusing on both immediate and long-term solutions to AMR, we aim to create a new global antibiotic pipeline, an ecosystem for antibiotic R&D and access, that is driven by public health needs. #Antibiotics #AMR ...
Endpoints for antibacterial trials: microbiologic
Просмотров 1066 месяцев назад
Endpoints for antibacterial trials: microbiologic Dianna Taylor, GARDP (Switzerland) Read the definitions on the REVIVE Antimicrobial Encyclopaedia here: revive.gardp.org/resource/endpoints-for-antibacterial-trials-microbiologic/?cf=encyclopaedia
Endpoints for antibacterial trials: timing of assessments
Просмотров 846 месяцев назад
Endpoints for antibacterial trials: timing of assessments Dianna Taylor, GARDP (Switzerland) Read the definitions on the REVIVE Antimicrobial Encyclopaedia here: revive.gardp.org/resource/endpoints-for-antibacterial-trials-timing-of-assessments/?cf=encyclopaedia
GARDP: An innovative public health approach to counter AMR
Просмотров 3667 месяцев назад
GARDP webinar, broadcast on 7 December 2023. Speakers: - Manica Balasegaram, Executive Director, GARDP - Angela Dramowski, Professor of Paediatric Infectious Diseases at Tygerberg Hospital/Stellenbosch University, and Principal Investigator of the neonatal sepsis observational study - Ramanan Laxminarayan, One Health Trust Founder and Director and GARDP Board Chair - Veronika Von Messling, Dire...
GARDP - Celebrating 5 years
Просмотров 1107 месяцев назад
Over the past five years, through our partnership model, GARDP has successfully developed a comprehensive portfolio of antibiotic treatments and we are well on our way of reaching our goal of delivering five treatments by 2025 (with four treatments in our current portfolio). We are also pioneering new access models with our innovator, manufacturing and distribution partners. Watch GARDP's work ...
Exploring opportunities to improve the treatment of gonorrhoea in Thailand
Просмотров 1747 месяцев назад
Gonorrhoea is the most common bacterial sexually transmitted infection in Thailand, affecting both men and women, particularly between 15 and 24 years old. In Thailand and globally the infection rate of gonorrhoea is increasing, with 87 million new cases estimated each year worldwide. Gonorrhoea is caused by the bacterium Neisseria gonorrhoeae, which has progressively developed resistance to gl...
Staying one step ahead of the bug
Просмотров 1677 месяцев назад
In 2020, an estimated 374 million new cases of curable STIs (gonorrhoea, chlamydia, syphilis and trichomoniasis) occurred among 15-49 year-olds worldwide, including 82 million cases of gonorrhoea. GARDP is partnering with Entasis Therapeutics on a new gonorrhoea treatment called zoliflodacin. A phase 3 trial is underway in four countries, including the Netherlands. Read more about our work on s...
The fight against drug resistant gonorrhoea
Просмотров 1837 месяцев назад
Gonorrhoea has progressively developed resistance to globally recommended treatments and has been identified by the World Health Organization as a priority infection urgently requiring new antibiotics. To address the lack of effective drugs, the Global Antibiotic Research and Development Partnership (GARDP) is developing a new treatment for gonorrhoea and is working to ensure it is available to...
Lead optimization
Просмотров 2108 месяцев назад
Lead optimization
Market interventions to improve access to antibiotics for resistant infections
Просмотров 2349 месяцев назад
Market interventions to improve access to antibiotics for resistant infections
Research brings hope for better antibiotic treatment for babies
Просмотров 2899 месяцев назад
Research brings hope for better antibiotic treatment for babies
Antibiotic shortages causes, consequences, and solutions
Просмотров 3539 месяцев назад
Antibiotic shortages causes, consequences, and solutions
Clinical trial platforms for new and neglected antimicrobials
Просмотров 2319 месяцев назад
Clinical trial platforms for new and neglected antimicrobials
Starting an antibacterial drug discovery screening programme
Просмотров 4589 месяцев назад
Starting an antibacterial drug discovery screening programme
Antimicrobial drug discovery: SAR optimization and QSAR
Просмотров 53010 месяцев назад
Antimicrobial drug discovery: SAR optimization and QSAR
Lifesaving treatment for neonatal sepsis in Uganda
Просмотров 14 тыс.Год назад
Lifesaving treatment for neonatal sepsis in Uganda
Adverse event / Serious Adverse event
Просмотров 435Год назад
Adverse event / Serious Adverse event
Project management in antimicrobial drug R&D
Просмотров 560Год назад
Project management in antimicrobial drug R&D
Confronting the growing threat of antibiotic resistance - 76th World Health Assembly
Просмотров 414Год назад
Confronting the growing threat of antibiotic resistance - 76th World Health Assembly
Life is on the line #PowerOfAntibiotics
Просмотров 1,2 тыс.Год назад
Life is on the line #PowerOfAntibiotics
How can non profit drug developers counter AMR?
Просмотров 162Год назад
How can non profit drug developers counter AMR?
Promise of artificial intelligence to antibacterial drug discovery
Просмотров 701Год назад
Promise of artificial intelligence to antibacterial drug discovery
Susceptibility testing in antibacterial drug R&D
Просмотров 489Год назад
Susceptibility testing in antibacterial drug R&D

Комментарии

  • @m.d.p.3844
    @m.d.p.3844 20 часов назад

    how does the body fight off these infections and break the biofilm when healthy? i can't imagine its a rare occurrence

  • @Chhhottaaadonn
    @Chhhottaaadonn Месяц назад

    When this medicine will come to india please tell me i have one of the most resistant strain

  • @Intwodeep902
    @Intwodeep902 Месяц назад

    any tips or thought on this article? What type of blood test would figure this out? www.ncbi.nlm.nih.gov/pmc/articles/PMC7558470/

  • @empwron9069
    @empwron9069 Месяц назад

    Thank you

  • @nitinsingh7197
    @nitinsingh7197 5 месяцев назад

    Thankyou so much sir..i am doing research on amr and was struggling with the definitions of these 3

  • @Abc-rx6tj
    @Abc-rx6tj 5 месяцев назад

    Worst "scientists" ever no concept or knowledge

  • @asian2700
    @asian2700 6 месяцев назад

    do you have any videos or articles on Fractional inhibitory concentration (FIC)?

    • @GARDP
      @GARDP 6 месяцев назад

      Here is our encyclopaedia page on Fractional inhibitory concentration (FIC): revive.gardp.org/resource/fractional-inhibitory-concentration-fic-index/?cf=encyclopaedia We will also take into account your suggestion for future video definition development - thank you for your comment !

  • @paulsomething8
    @paulsomething8 7 месяцев назад

    Even though it has always had serious side effects and complications, it is still seen as such a "quick fix infection" that no one takes seriously. I applaud the work you are trying to do.

  • @user-cc5qv9wr6v
    @user-cc5qv9wr6v 8 месяцев назад

    Vidyo sek

  • @alexojideagu
    @alexojideagu 8 месяцев назад

    Something amazing happened in my kitchen. I created a glass trap for fruit flies to drown using fermented liquid. I also put in some grapes to ferment and help attract fruit flies. It worked great for 1 month, until amazingly a thick slimy Biofilm formed floating on the surface, partially thanks to the grapes decomposing. Amazingly, not only did this now prevent the flies drowning anymore, but helped them started BREEDING maggots on top of the Biofilm! Bacteria and insects worked together to defeat my trap and start breeding together in symbiosis. Amazing.

  • @hayfordodoi7178
    @hayfordodoi7178 10 месяцев назад

    Very informative and helpful guys. Bless you

  • @joanitamukyala1512
    @joanitamukyala1512 10 месяцев назад

    Hi Doctor Flavia. This is Auntie Liam. Auntie to baby of Kyozira Evelyn. I would like to extend my sincere gratitude to you and the team of Mulago Women's Hospital NICU. Today Liam is alive because of your dedication to our little ones. May the Almighty continue to use you and bless you immensely.

  • @afzaldanish5266
    @afzaldanish5266 10 месяцев назад

  • @samuelmanu-boateng7984
    @samuelmanu-boateng7984 Год назад

    Great

  • @sweetgirl-mv5dt
    @sweetgirl-mv5dt Год назад

    Thanks

  • @mishalshafiq6186
    @mishalshafiq6186 Год назад

    What is R and D

  • @dustinlambert1255
    @dustinlambert1255 Год назад

    😁 *promosm*

  • @lozarkderccy3254
    @lozarkderccy3254 Год назад

    Thank you thank you! This was so helpful!

  • @danash5460
    @danash5460 Год назад

    Thank you 🙏 soooooo much

  • @acalp
    @acalp Год назад

    It absolutely amazing. So much information in a single video

  • @phanankosi2009
    @phanankosi2009 Год назад

    "The nurturing power of nature!" Great talks, great work!

  • @kentharry1
    @kentharry1 Год назад

    Very informative!

  • @jameswilliams3443
    @jameswilliams3443 Год назад

    Good news Good new💃💃 to all HIV patient *Dr Alued on RUclips* have prouder the herbal remedy that have been curing people from HIV I was cured search him on RUclips

  • @danielkelly3013
    @danielkelly3013 Год назад

    God bless herbalist doc Odion for curing me completely with the use of herbs after years of being a Chlamydia patient with no solution from the medical doctor. ruclips.net/channel/UCLJPudFNpftjjnmFkkPGt7g Doc Odion's has the best herbal cure for all kinds of diseases and I've seen a lot of great testimonies about his herbal treatment.

  • @gdp2102
    @gdp2102 2 года назад

    Very good definition, i wish it should have been given in description. Bit fast here.

  • @matthewp506
    @matthewp506 2 года назад

    i am intersted in anti-aging trails

  • @matthewp506
    @matthewp506 2 года назад

    i have been searching for this type of technology all my life ever since i was able to understand things i am interested in joining a trail

  • @matthewp506
    @matthewp506 2 года назад

    please contact me about the trail i am interested in joining

  • @ragavenragav2576
    @ragavenragav2576 2 года назад

    Hbv chronic cure possible? Medicine when expect?

  • @ragavenragav2576
    @ragavenragav2576 2 года назад

    Hbv patients marriage possible?

  • @calcaneus2000
    @calcaneus2000 2 года назад

    Aren't we trying to solve the problem at the wrong end of the equation? A diabetic wound or lung infection is the business end of a long road of problems that have not been stopped for many years in a patient's life. Is this monetarily feasible in the real world to continue to allow people to drain healthcare finances with psychosocial problems that they elect to ignore for a long period of time?

  • @sukmydikgoogle5666
    @sukmydikgoogle5666 2 года назад

    It's been years now and still no hope when is this zoliflodacin wonder F ing drug coming out!

    • @sukmydikgoogle5666
      @sukmydikgoogle5666 2 года назад

      @Aleksa yes I have chronic prostatitis cause by gonorrhea infection.

    • @sukmydikgoogle5666
      @sukmydikgoogle5666 2 года назад

      @Aleksa you will have to excuse me since my Russian isn't really good at all but are you asking me for my Instagram?

    • @Chhhottaaadonn
      @Chhhottaaadonn 25 дней назад

      Is your gonorrhoea ceftriaxone resistant

  • @ragavenragav2576
    @ragavenragav2576 2 года назад

    Sir any some one cure chronic hbv?

  • @hannahsangil4501
    @hannahsangil4501 2 года назад

    *People always say there will never be another great Herbalist like the old, that i disagree with because I found a herbalist on RUclips called **#DrMadida** that is special and genuine, this herbalist cured i and my husband of our herpes virus.*

  • @dejaluc3579
    @dejaluc3579 2 года назад

    Words of appreciation to #DrBalogun who cured my herpes completely with his natural herbs ruclips.net/channel/UCTLVdF3iPu91GLSUJhqtQLA

  • @manishaent6872
    @manishaent6872 2 года назад

    Very well explained !

  • @judith2182
    @judith2182 2 года назад

    All thanks to (Dr Obulor) herbal protocol on RUclips we're I found what helped with my herpes and HSV2 along with a vegan diet .

  • @judith2182
    @judith2182 2 года назад

    Wow! I am so excited I just got rid of Herpes permanently within 9 days. I’m so filled with joy right now all thanks to Dr Obulor on RUclips ✅

  • @ryujenshogun
    @ryujenshogun 2 года назад

    Bacteriophage therapy seems to be a vialable alternative if ever a bacteriophage is discovered for mycobacterium tuberculosis, is it possible to treat pulmonary tuberculosis if administered systemically (IV). Or will the pathophysiology of TB like macrophages covering up for TB prove to be a difficult obstacle for bacteriophage therapy if ever this is discovered/possible. Thank you

  • @umarisah669
    @umarisah669 2 года назад

    Your service toward humanity is indeed a great one Dr Ogoh, I'm permanently free from Genital herpes after taking his medication. Thanks to Dr Ogoh on RUclips 🌿

  • @colehawkins3037
    @colehawkins3037 2 года назад

    Getting a permanent medicine to cure any type of disease 🦠 such as herpes or any other diseases is the best thing for anyone living with such disease 🦠 get yourself a cure Dr Oseghale Sunday herbal home’s medicine !

  • @cherishchannel452
    @cherishchannel452 2 года назад

    Great experience doc, you are a godsent Dr Ebhariagbe on RUclips, keep up the good work, I am completely free from HSV2 ..,

  • @jennykristen8733
    @jennykristen8733 2 года назад

    At first i thought it was the end of the world for me but today i found the solution for the genital herpes virus that almost ruined my marriage due to multiples of outbreaks Thank so much Dr. kwaloe on you tube, You are indeed a genius

  • @godspowergodbless4884
    @godspowergodbless4884 2 года назад

    My first reaction of HSV2 was very bad and it had me worrying all time everything changed after I meant with Dr Oseghale Sunday Herbal Home that gave a permanent solution for curing HSV2 and now I can say that I’m free from HSV2 no reactions anymore no hives or itching for a long while now thank you doctor !

  • @kellybaldwin9205
    @kellybaldwin9205 2 года назад

    Glory be to God almighty after many years, finally i have found joy with the help of DR JADU OINDIN on RUclips, the great herbal doctor help me cure my HSV 2, with the herbal medicine product I ordered. I will forever be greatful to DR JADU OINDIN on RUclips thanks 🙏 herpes gone finally ….❤️

  • @berrybanky2284
    @berrybanky2284 2 года назад

    I want to appreciate dr osaba on RUclips, I was cured from herpes virus the herpes of his herbal medicine

  • @carolynboyanton7679
    @carolynboyanton7679 2 года назад

    Really appreciate you DR JADU OINDIN on RUclips for bringing back happiness, for giving me a permanent cure to my HSV2. Thank you so much, friends join me to thank him for what he has actually done for me and I pray to you all for a good life and good health, and most especially to you DR JADU OINDIN

  • @sunday6371
    @sunday6371 2 года назад

    All thanks to Dr Abiola on RUclips for curing me permanently from HSV-1 and HSV2 virus 💕💗 #drabiola

  • @sunday6371
    @sunday6371 2 года назад

    All thanks to Dr Abiola on RUclips for curing me permanently from HSV-1 and HSV2 virus 💕💗 #drabiola

  • @sunday6371
    @sunday6371 2 года назад

    All thanks to Dr Abiola on RUclips for curing me permanently from HSV-1 and HSV2 virus 💕💗 #drabiola