Sara Elena Ramírez Vargas is an American actor. Born in Mazatlán, Sinaloa, Ramírez moved from Mexico to the United States at eight years old, eventually graduating with a fine arts degree from the Juilliard School.
Ramírez began acting in Broadway productions, making their debut in Paul Simon's The Capeman, and later ventured into film and television roles. Ramírez's breakthrough came with their portrayal of the original Lady of the Lake in the 2005 Broadway musical Spamalot, winning the Tony Award for Best Featured Actress in a Musical. On Grey's Anatomy, they portrayed Dr. Callie Torres, one of the longest-running LGBT characters in US television history, appearing in 11 seasons and 239 episodes. Ramírez's volunteered addition of the character's bisexuality marked one of the earliest series regular queer roles on primetime television. After departing from the series, Ramírez came out as bisexual and later non-binary, using they/them pronouns. They later portrayed the bisexual and non-binary roles of Kat Sandoval on Madam Secretary and Che Díaz on And Just Like That..., respectively.