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Can irreversible inhibitors side effects be permanent?

tghis pill gave a a boner that lasted 48 hours. Thank god i was in thailand

Even though this is 2 years old, it's very interesting, and should be a "special topic" in a molecular biology class (IMO). Good job explaining the science, as well as potential risks.

Simple and Short and actually what you titled in the Video! THANK YOU

Thank you for this valuable work 😊

Thank you! good illustrations

I liked the explanation very much it's great

Thank u

Can you please share the reference for the last picture shown in the video? (30% ...),

Is it possible to tell me what the difference between a pharmaceutical chemistry and medicinal chemistry?

Excellent

Where does formulation chemist fall?

1:45 compound/inhibitor= TS-ANALOG

0:50 smh modern beauty standards

Can you recommend me a book which covers this topic in detail

Thank you for posting this! Something I'm a little confused about: you stated around 1:04 that a peptide bond is formed via "a dehydrogenation or condensation reaction". Isn't dehydrogenation the removal of JUST hydrogen? So, it wouldn't actually be a dehydrogenation reaction in the case of a peptide bond forming?

The video is great. But speak louder..you voice comes out as a muffle

This is soo helpful, thank you soo much Daniel for going into the details without overcomplicating things. Keep up the excellent work

Why they are called beta

By the way generally only pharmacist do medicinal chemistry

Early day scientifics sometimes consisted of 1 person. A team is best, but its possible with less people. Thanks for this information.

I am currently in pharmacy school and I hope to continue in the field of medicinal chemistry,But in Iraq we only have a pharmaceutical chemistry program. The question is whether pharmaceutical chemistry and medicinal chemistry have the same focus in work and research.

Hello! Thank you for great video! I am 4th year undergraduate student, and i am choosing between bioinformatics and experimental biology now. Could you please answer do computational biologists/chemists in addition to data analysis, plan experiments and make hypotheses? That is, how much biology/chemistry are there in bioinformatics? Can computational scientist, for example, suggest some new experimental technology?

Thanks you sir your videos are helping me to get some knowledge about medicinal chemistry... 🎉❤

I need that drug

My Doctor forgot to give me this drug period AMEN.

Thank you for such clear informative videos.

This was extremely helpful! Thank you, good sir.

D stands for distribution. 🙂

my husband recovered within 3 days of beginning paxlovid but immediately began experiencing high blood pressure and despite high blood pressure meds within one month suffered a stroke. if I had know this I would have insisted he take one baby aspirin a day.

Perfect 👌🏻 ❤

id say both are likely and are not mutually exclusive, in fact id say that it is absurd to assume that selection can occur without the degree of variation (of one at least) still being capable of performing the necessary catalyses. Id also say that over time selection would move towards a lock and key level of fit. But ive been wrong before :) 10/10

how is this video so small this is such a good video man seriously

Hello, I am an Organic Chemistry post-graduate student, and even at this point understanding the drug discovery process can be chaotic. Even though I like Organic Chemistry I am very curious about other disciplines and I would like to get involved in other fields in the future. Your video provides great insights, thank you!

Thank you!

This made me break out on a neck rash. And it made me feel like I was in the fight of my life. After 3 days I had to discontinue.

This was really helpful :) I'm a new PhD student starting a project about targeting GPCR-mediated extracellular acid sensing by tumor cells and I'm just starting to learn why GPCRs are such common targets of drugs. In the future, maybe the exact GPCRs responsible for binding protons can be identified and targeting them can limit tumor cells from positively responding to the low acidity conditions they generate!

Great stuff man, currently doing my VCE Yr12 biology and I've watched many videos however this one explains everything very clearly others try to keep it simple or too complicated.

This video is so helpful for me, thank you so much.

Thank you for the information.

Last virus I was in ICU and step-down for 7 days. Recently got Covid...J and J primary and Moderna.booster....got Paxlovid ...was only sick for 3 days...minor temp of 99.1..... the metallic taste was terrible....tired with a slight headache......better than full blown Covid I say!

This is a miracle dose of pills. Started feeling better after first dose of 3 pills after suffering from fever for 2 days straight. Took 3 pills the evening I got the prescription, and I was finally able to sleep that night. Fever came down considerably. I didn't care about the after taste, I just needed relief from the pain and fever.

Pos

Sir I am doing bachelor degree in chemistry and want to be in pharmaceutical industry in future. I planed to go for masters in drug discovery but I am confused that in which field in the drug discovery I should go for?medicinal chemist , analytical chemist, computational chemist. Please guide me sir about it?

Decently explained🥰 sir please share your email address I have some queries which I want to discuss with you?

where would chemical biologists fall under or are they the same as medicinal chemists ?

I am an Analytical chemists and have always liked the computation in the pharmaceutical industry. we go we go.