Видео 108
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32:26

ESMO 2024 - Day 3

22:46

124. Metastatic HER2- Positive Breast Cancer

31:24

90. On the Road with Dr. Harold J Burstein

58:12

ESMO 2024 - Plenary Special

We have finally come to the end of ESMO 2024, and as is now tradition, Michael and Josh conclude their epic journey with a special episode highlighting their absolute favourite practice-changing selections from the Plenary Sessions. As always, ESMO brought a selection of wonderful studies that truly deserve the title "practice changing." As always, a huge thanks to everyone who joined us on this amazing journey.
Stay tuned to Oncology for the Inquisitive Mind in the coming weeks as we will be starting our ESMO 2024: Retrospective miniseries, where we speak to experts in the areas of breast, lung, GI, GU and skin cancers and get their opinions on the goings on in Barcelona.
PEACE-3
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Видео

32:26

ESMO 2024 - Day 4

Просмотров 521 день назад

The end of the road approaches, and ESMO 2024 will soon be in the rearview mirror. However, each new day brings new, incredible advances in the treatment of cancer. Today, Josh and Michael dive into biomarker analyses, overall survival updates and new antibody-drug conjugates galore. Listen on for our penultimate summary of ESMO. Studies discussed in this episode: Biomarker analysis of PEACE-1 ...

22:46

ESMO 2024 - Day 3

Просмотров 821 день назад

Day three of the European Society of Medical Oncology Congress had many exciting and potentially practice-changing trials in the genitourinary space. Gone are the days of urothelial cancer having a single treatment and prostate cancer only having androgen deprivation therapy. They look at biomarkers for ADC response in bladder cancer, the use of lutetium upfront for metastatic hormone-sensitive...

30:07

ESMO 2024 - Day 2

Просмотров 2521 день назад

Josh and Michael's Spanish Sojourn continues with their review of Day 2 of the European Society of Medical Oncology. Your hosts have been on their feet rushing from lecture theatre to lecture theatre, attending as many incredible presentations and soaking in as much practice-changing information as their brains could manage. In this episode, Michael and Josh report presented data ranging from s...

24:07

ESMO 2024 - Day 1

Просмотров 3028 дней назад

The European Society of Medical Oncology Congress has begun, and Michael and Josh are on the ground, bringing you breaking studies and heartbreaks along with some important updates in the science and art of medical oncology. Michael and Josh cover a range of tumour types on day one, a slight deviation from our regular coverage. They look at hepatocellular carcinoma, renal cancers, and breast ca...

124. Metastatic HER2- Positive Breast Cancer

31:24

124. Metastatic HER2- Positive Breast Cancer

Просмотров 242 месяца назад

Metastatic HER2-positive breast cancer continues to dominate headlines, and new therapeutic options continue to be found for those afflicted with the disease. Before trastuzumab (anti-HER2 therapy), the overall survival for this cohort of patients was less than two years. As technology and treatments changed, it can boast an extended survival well beyond five years in numerous studies, with man...

90. On the Road with Dr. Harold J Burstein

58:12

90. On the Road with Dr. Harold J Burstein

Просмотров 227 месяцев назад

In this episode, Josh interviews Dr Harold Burstein. A graduate of Harvard University and Harvard Medical School, Dr Burstein’s initial PhD was in cellular immunology. After receiving his oncology fellowship at the Dana Farber Cancer Institute, he joined the staff in 1999. Hal has a particular interest in breast cancer and has participated in national and international clinical trials while als...

89. Spotlight - Biotech: Interview with Dr Jeff Jones from Cullinan Oncology

31:56

89. Spotlight - Biotech: Interview with Dr Jeff Jones from Cullinan Oncology

Просмотров 487 месяцев назад

Today, on this mid-week special, Oncology for the Inquisitive Mind is delighted to welcome Dr. Jeff Jones, a haematologist, oncologist and the Chief Medical Officer of Cullinan Oncology. Biotech companies are at the forefront of novel drug development, and it is fascinating to take a look behind the curtain and glimpse a small part of how targets are chosen and developed. This includes areas of...

88. On the Road with Dr. Geoffrey Shapiro

29:19

88. On the Road with Dr. Geoffrey Shapiro

Просмотров 298 месяцев назад

We return to the Dana Farber Cancer Institute this week as part of our "On the Road" series and interview the multitalented Dr. Geoffrey Shapiro. Dr Shapiro completed his medical training at Cornell University and received his PhD in 1987. His passions lie in early-phase drug development and clinical trials, with a specific flair for cell cycle and DNA repair inhibitor therapeutics. Dr. Shapiro...

32:21

87. On the Road with Dr. Eric Winer

Просмотров 458 месяцев назад

Today, we interview Dr. Eric Winer, our second guest in our mini-series "On the Road". Dr Winer is no ordinary Oncologist; he is a prolific clinician and researcher, despite being born with haemophilia and living with the consequences of early treatment for this, including HIV. In this episode, OFTIM explores his formative years, challenges and triumphs as he provides unique insights as both a ...

45:07

86. On the Road with Dr. Erica Mayer

Просмотров 278 месяцев назад

Today, we interview Dr. Erica Mayer as our first guest in the "On the Road" mini-series. Dr. Mayer is a renowned breast cancer oncologist at the Dana Farber Cancer Institute. Each week for the next seven weeks, Michael and Josh will introduce a new guest to share their wealth of experience, expertise and wisdom, covering all the essential topics from career development, mentorship and necessary...

29:39

85. Spotlight: Year in Retrospect: 2023

Просмотров 278 месяцев назад

Oncology for the Inquisitive Mind is back, and we have a blockbuster year ahead! Before we get there, we have our year in review 2023. Michael and Josh have poured over the treasure trove of pivotal trials from 2023 to bring you the best studies (in our opinion) from the last 365 days! We used various complex metrics involving no science or maths at all. When you thought you were free from onco...

82. Metastatic triple-negative breast cancer (TNBC)

36:03

82. Metastatic triple-negative breast cancer (TNBC)

Просмотров 2799 месяцев назад

Oncology for the Inquisitive Mind would like to issue a formal mae culpa to our listeners. You have joined us for over 12 months and over 80 episodes and listened to our ramblings and bad jokes. And it has taken 80 episodes for us to realise we have neglected the crucial and exciting subject of metastatic triple-negative breast cancer (TNBC). But fear not! We will rectify this egregious oversig...

Fireside Chats 2. Time toxicity in early phase clinical trials

22:28

Fireside Chats 2. Time toxicity in early phase clinical trials

Просмотров 1710 месяцев назад

For patients with advanced cancer, early-phase trials may represent the last best hope of significant anticancer response. For clinicians, every early phase trial holds virtually unlimited promise and hope of becoming the next immunotherapy or hot antibody-drug conjugate. However, early-phase trials also come with significant uncertainty of efficacy, toxicity and even dosing. A recent Limbic ar...

81. San Antonio Breast Cancer Symposium Update

29:56

81. San Antonio Breast Cancer Symposium Update

Просмотров 6010 месяцев назад

San Antonio Breast Cancer Symposium is here, and this year, OFTIM (Oncology for the Inquisitive Mind) is bringing you the latest and greatest in all things breast cancer. With over 10000 attendees, the research and vibrant discussions did not disappoint, with updates, controversies and complexities. Taking centre stage were PIK3CA mutation treatments, updates on CDK4/6 inhibitors and the age-ol...