- Видео 79
- Просмотров 38 711
NPP Journal
Добавлен 19 мар 2021
Welcome to Neuropsychopharmacology (NPP), the official publication of the American College of Neuropsychopharmacology (ACNP).
NPP is a leading peer-reviewed medical journal focused on the intersection of psychiatry and neuroscience. Our mission is report discoveries and developments in brain research while promoting training and outreach.
NPP is a leading peer-reviewed medical journal focused on the intersection of psychiatry and neuroscience. Our mission is report discoveries and developments in brain research while promoting training and outreach.
npp's "Meet the Author" with Dr. Lucas Trambaiolli
Join us as we speak with Dr. Lucas Trambaiolli (McLean Hospital and Harvard Medical School) about his recent Neuropsychopharmacology publication, "Translation of monosynaptic circuits underlying amygdala fMRI neurofeedback training".
You can read the full article here: www.nature.com/articles/s41386-024-01944-w
For more information about the NPP intership and application instructions, please visit: x.com/npp_journal/status/1825615392108110147
Want to get in touch with Dr. Trambaiolli?
Twitter/X: x.com/LRTrambaiolli
You can read the full article here: www.nature.com/articles/s41386-024-01944-w
For more information about the NPP intership and application instructions, please visit: x.com/npp_journal/status/1825615392108110147
Want to get in touch with Dr. Trambaiolli?
Twitter/X: x.com/LRTrambaiolli
Просмотров: 45
Видео
Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncov...
Просмотров 542 месяца назад
Researchers are interested in understanding the biology of why some people are more likely to overconsume substances. Some substances are difficult to study-people might not admit to illegal substance abuse or to how much alcohol they drink. But Americans are more likely to accurately recall and share how much coffee they drink-which is related to how much caffeine they consume. And so a team o...
npp's "Meet the Authors" with Dr. Helen Collins
Просмотров 1234 месяца назад
Join us as we speak with Dr. Helen Collins (University of Oxford) about her recent Neuropsychopharmacology publication, "Rebound activation of 5-HT neurons following SSRI discontinuation". You can read the full article here: www.nature.com/articles/s41386-024-01857-8 For information about humane and responsible preclinical research, visit: nc3rs.org.uk/ Want to get in touch with Dr. Collins? Em...
C-reactive protein moderates associations between racial discrimination and ventromedial prefront...
Просмотров 2184 месяца назад
Scientists have been amassing an increasing amount of evidence about the impact of racial discrimination and racial trauma, including how it can have an impact on brain regions involved with threat vigilance and emotional regulation. At the same time, there’s evidence that increased engagement in those areas has been linked to increased risk of mental health problems like depression, and they a...
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate...
Просмотров 876 месяцев назад
There’s a hormone called ghrelin that’s secreted in the stomach, and when someone is hungry it contributes to that feeling of hunger and the need to search for food. But neurological studies have suggested that ghrelin might also play a role in compulsivity and impulsivity, and it might be related to substance use disorders. Rebecca Boeme is an assistant professor at Linkoping University in Swe...
npp's "Meet the Authors" with Drs. Cellas Hayes and Frankie Heyward
Просмотров 857 месяцев назад
Drs. Cellas Hayes and Frankie Heyward join us to talk about their recent Early Career Commentary published in Neuropsychopharmacology (npp): "Academic ethics of mental health: the national black postdocs framework for the addressment of support for undergraduate and graduate trainees." This commentary discusses the Emergency Support Program (ESP), a program launched by the National Black Postdo...
Spotlighting SHAPERS: Sex hormones associated with psychological and endocrine roles
Просмотров 2018 месяцев назад
Dr. Nicole Petersen is an assistant professor in the department of psychiatry and behavioral sciences at UCLA. Her commentary is a new paper in the journal Neuropsychopharmacology, called “Spotlighting SHAPERS: sex hormones associated with psychological and endocrine roles.” Dr. Petersen starts the paper describing an unnamed signaling molecule that can affect the physical structure of the brai...
npp's "Meet the Authors" with Dr. Cassie Boness, Kanak Kataria, and Dr. James Morris
Просмотров 939 месяцев назад
Dr. Cassie Boness, Kanak Kataria, and Dr. James Morris join us to talk about their recent Early Career Commentary published in Neuropsychopharmacology (npp): "Should we embrace the term ‘preaddiction’?" This commentary discusses the use of the term “preaddiction” to improve identification of and interventions for early stage, or less severe, manifestations of substance use disorder (SUD). Read ...
Comparable roles for serotonin in rats and humans for computations underlying flexible decision-m...
Просмотров 13410 месяцев назад
Serotonin is a critical chemical when it comes to a number of psychiatric conditions, such as OCD, where it seems to play a particular role in cognitive flexibility. That is, serotonin levels are related to the fact that someone is perseverating on intrusive thoughts or compulsions and isn’t able to be as flexible as otherwise would be necessary. Trevor Robbins, professor of cognitive neuroscie...
npp's "Meet the Authors" with Drs. Alexandra Moussa-Tooks and Heather Ward
Просмотров 12911 месяцев назад
Drs. Alexandra Moussa-Tooks and Heather Ward join us to talk about their recent Early Career Commentary published in Neuropsychopharmacology (npp): "Practical recommendations to improve retention of underrepresented minorities in science and medicine: an early career perspective." This commentary discusses strategies to improve mentorship and enhance the retention of underrepresented minorities...
Integrating public health and translational basic science to address challenges of xylazine adult...
Просмотров 49Год назад
The drug naloxone, otherwise known as Narcan, is a critical tool in reversing fentanyl overdoses and reducing mortality. But now fentanyl is appearing on the streets adulterated with a drug called xylazine. Justin Strickland, assistant professor at Johns Hopkins University School of Medicine, and Cassandra Gipson-Reichardt, associate professor in the department of pharmacology nutritional scien...
The why, when, where, how, and so what of so-called rapidly acting antidepressants
Просмотров 105Год назад
Sanjay Mathew is a professor and vice chair for research at Baylor College of Medicine and director of the Mood and Anxiety Disorders Program. He’s one of the two authors of a recent review paper in the journal Neuropsychopharmacology, “The why, when, where, how, and so what of so-called rapidly acting antidepressants.” With his colleague Alan Schatzberg, professor of psychiatry and behavioral ...
npp's "Meet the Authors" with Dr. Kevin Clancy
Просмотров 77Год назад
Dr. Kevin Clancy joins us to talk about his recent article published in Neuropsychopharmacology (npp): "Circulating PACAP levels are associated with increased amygdala-default mode network resting-state connectivity in posttraumatic stress disorder." This article reveals novel insights into the eural circuit dysfunction in PTSD and how the PACAP system confers risk through a disruption of intri...
AI-based analysis of social media language predicts addiction treatment dropout at 90 days
Просмотров 155Год назад
In-person treatment for substance use disorders is an incredibly important tool, but there’s a high failure rate - more than 50 percent of people who enter drop out within the first month. There hasn’t been a highly accurate method of identifying who might leave and who might succeed, and knowing this could help centers allocate resources to give the right type of assistance to the right people...
Oxytocin effects on amygdala reactivity to angry faces in males and females with antisocial perso...
Просмотров 726Год назад
Antisocial personality disorder, or ASPD, is a difficult disorder to study. There have been studies on psychopathic individuals, and on youth with psychopathic traits, but most studies on ASPD to date have been on incarcerated adults. A team of researchers at Heidelberg University wanted to study individuals who are not incarcerated and see what these findings could elucidate about the brains, ...
npp's "Meet the Authors" with Dr. Siara Rouzer, Leanna Kalinowski, and Erin Kaseda
Просмотров 106Год назад
npp's "Meet the Authors" with Dr. Siara Rouzer, Leanna Kalinowski, and Erin Kaseda
To dismantle structural racism in science, scientists need to learn how it works
Просмотров 118Год назад
To dismantle structural racism in science, scientists need to learn how it works
Dr. Olusola Ajilore discusses the link between racial discrimination, inflammation, and depression
Просмотров 206Год назад
Dr. Olusola Ajilore discusses the link between racial discrimination, inflammation, and depression
Neuropsychopharmacology Reviews: Neurotherapeutics
Просмотров 218Год назад
Neuropsychopharmacology Reviews: Neurotherapeutics
Neuropsychopharmacology Reviews: Epigenetics
Просмотров 97Год назад
Neuropsychopharmacology Reviews: Epigenetics
Smoking throughout pregnancy may contribute to emotional problems in children
Просмотров 30Год назад
Smoking throughout pregnancy may contribute to emotional problems in children
Neuropsychopharmacology Reviews: Biomolecular Discovery: Mechanisms, Therapeutics, and Biomarkers...
Просмотров 25Год назад
Neuropsychopharmacology Reviews: Biomolecular Discovery: Mechanisms, Therapeutics, and Biomarkers...
HIV infection may raise risk of cocaine abuse
Просмотров 105Год назад
HIV infection may raise risk of cocaine abuse
Neuropsychopharmacology Reviews: Neurodevelopment and the Origins of Brain Disorders
Просмотров 84Год назад
Neuropsychopharmacology Reviews: Neurodevelopment and the Origins of Brain Disorders
Neuropsychopharmacology Reviews: Impact of Stress on the Brain: Pathology, Treatment and Prevention
Просмотров 61Год назад
Neuropsychopharmacology Reviews: Impact of Stress on the Brain: Pathology, Treatment and Prevention
Please please never never never never try it. It will affect your life. Im so regret of taking it.
This more or less confirms a suspicion I had in my personal life. I overconsume coffee, my parents had high tolerances for coffee, my grandparents spent all day drinking coffee. It just seemed to be a familial insensitivity to the coffee and the caffeine.
I beat addiction with mushrooms and lsd
Psilocybin mushrooms show promise in supporting mental health.
Can I get em?
Will he be On instgram?
My journey to recovery was aided by the therapeutic potential of mushroom
Can he send to me in NYC ?
Clowns
Cringe
So the fact that t cells and ace dont function the same in people and mice.... THE EXACT ISSUE WITH THE VAX EXPERIMENTS THEY WENT WITH AS SUFFICIENT...
NO
Thanks for uploading the Interview! Really interesting
Great Talk! Thanks for Uploading. It would be a nice addition if you put links to relevant papers in the description aswell 😊
This whole idea of your institution having a youtube channel is highly beneficial for citizens out here. Produce it this is good!!!
My ability to discuss this topic is comparable to the ratio of the earth to the sun in regards to individuals who have studied this. videos like this being up here for free live above value. Beyond value, yes. Thank you.
Legal? 😅
Awesome RUclips channel
Delysid is the answer. Kid tested, Mother approved! 😉👍
Absolutely false! I couldnt be sad! I tried and i have alot going on! I was watching Fire in the Sky and was seeing and feeling shit. Was terrified!
lol skill issue
You were unable to feel sad and that scared you?
Friend
SWIM has had life altering experiences with the help of said substance. They kicked a long opiate and benzo addiction almost immediately within the first week lowering the dose slowly with no problem, much easier without said substance/tool. It can be used in many beneficial ways to change your views, but with that said it also needs to be done in a certain setting. Personally speaking, i would not have the same type of experience in a doctors office with wires hooked up, as i would outdoors in the public or in my room where im comfortable with people im familiar with. This is where science and medicine needs to really pay attention to each specific individual. It's not right for some and for others it can be the key to success as it broadens your way of thinking and perspective. It also needs to be monitored closely how often you dose because you can get "ate up" from it. I lost two jobs because i took too many in a short period of time as a young teen... Just my two cents as someone who could benefit greatly from it but doesn't dare get anything off the streets.
Ayahuasca and Psilocybin therapy have changed my entire life for the better. LSD I’m sure works very similarly, I have many years of experience with almost all the psychedelics for healing trauma, depression, and addiction. For me personally it works better than any pHARMaceuticals from the doctors ever did.
Love the Siri-like "sympathetic" female administrator questioner.
He seems to be describing a Dead show without the meth predators...
Too many people want very badly to believe one thing or another so I can't trust anything I hear. Weed is available. You are going to find many people have tried it. Many people with schizophrenia are going to have been smokers. Many people without are too. It does seem to affect sleep and stress and depression with constant regular use; but so does anything that suppresses the nervous system. If you don't smoke for a month, anything you're worried about goes away. Responsible people will not have a problem.
The effective low low dose was 13mcg for anyone that was wondering
What's strange about this study is the participants reported feeling no drug effects at 13mcg. I'm not a lightweight and I definitely feel the effects at even 8mcg.
For perspective: a 1960s "death and rebirth" 8-hour trip is about 250mcg (Orange sunshine had 300.) A 1970s dose of "disco acid" was about 75 to 100 Mcg. That was supposed to make a night at the disco more fun, but not make you deeply introspective or to see the walls melt. I used to take a quarter hit of disco acid, and it was enough to give me a nice mild buzz. So 13 mcd would be about half of that. It would have an effect, but a very mild one.
@@rd5854 I think that they felt it but did not know it because they did not know what they should be looking for. They did not know that their mild changes in perceptions were caused by the LSD. Like how sometimes a person who smokes weed for the first time will report not being high.
It is because you know you have taken it. The brain is a powerful thing.@@rd5854
@@rd5854 But maybe not to the mind of someone who's never had a full trip before. They literally have no idea what to expect. In a similar way not everyone gets stoned for the first time (i.e. they don't have enough to notice).
Ssri's suck. Look up how many mass shooters are on them. That's the real problem, not inanimate objects
You sure it's not correlation rather than causation? Many school shooters are depressed and many school shooters are on SSRIs because they're depressed. Sure, the SSRIs may not be effective enough to prevent them from comitting atrocious acts of violence, but they would be just as depressed without them.
@@spopydude69You've obviously never been on, or known someone on SSRI's or SNRI's. Because if you did, you'd know that's complete BS. I have _never_ met one person on those drugs who's not completely fucked. Depression leads to suicide. SSRI's and SNRI's turn suicide into homicide. Cut and dry. They have not helped one person outside of the first 4 to 8 weeks. After that you're fucked.
ssris create government obeying zombies end of discussion
I can't find a source anywhere for any good psychedelics in my area, I suffer some pretty bad depression and i got a chance to try K and man it was a miracle substance, I felt free,the only high or euphoria was from the relief of my vices being released, that's exactly what it did
The psychedelic experience is temporary but many people have permanent results
Mushroom completely turned my life around and my anxiety and panic attack disappeared and my personality changed into a much more generous loving person
🍄
Look up how to grow your own shrums, or extract from acacia bark.
@@derickmartenshow much and which mushrooms u take ? Should I take every day mushrooms or better every day Microdosing?
Finally! Torquemada retreats, reason advances. ☮
Oh sorry me and my childrn are not the neighbors where i live
@Mark Smith hate to tell you I don't do that drug I'm not the Miller child abusing animal abusing drunk driving thieves neither me nor my children are them liars cause I turned them in my self that right where I lived they sell all kind drugs threaten to kill me and my kids and there liars police already know there liars and oh yea me and my children don't steal other ppl mail neither or forge there names neither
Alcoholic grammar?
@@libertariantranslator1929 I don't drink so shut the hell up with your lies
Are you kidding me microdosing do you know how much a hit of acid is? It's microdosing
How do you micro dose a micro dose ?
@ryankottke8120 I don't I haven't done LSD since I was 23 after doing DMT I never looked back at LSD ever again. I was implementing you can't microdose LSD it's impossible
lmao this is funny and ignorant, i love it
@@Ryan-xq3kl I think I was micrdosing DMT but then I saw a tiny crystal on the ash and said to myself this shouldn't be too bad. But once I hit that shit I went from reality to OMFG WTF IS GOING ON HERE WHY AN I TRAVELING THROUGH SPACE, I don't see anyone micrdosing DMT either cause that will change your whole life to see the real truth of our existence and when we see when everyone dies. Something that supposed to last 5 minute felt life I live a while another life from birth to death in 5 minute. Then what takes the cake is your hanging out in a tunnel on the edge of another universe taking to GOD himself and no she he's not a physical being god is pure energy every question you asked it was immediately answered. I saw the my next journey when I pass this world and saw few planters with 2 suns ones much further away than the other one. But it feels right. Then once he tells you how simple the secrets to the universe is it pulls you from this dream reality check instantly and your faced around the ones you knew before you left now you have no idea who or what they. I couldn't talk and had to relearn everything for the next 20 minutes. Every tolerance in your body has be ZEROED OUT. I never touched LSD again or shrooms I couldn't smoke weed for 9 months coffee felt like the first time drinking it and got me so high of caffeine beer only took a half a can and drunk AF. EVERYTHING on this planet looked and felt differently. Religion became a fraud setting through every lie around you that was taught by generations to s scare you in thinking everything in the book of BS were true events then realized that Jesus was an alien sent from his father in space on his ship after creating him for months ago. All this from one hit of DMT. LEARN Knowledge WHILE sleeping in your dreams from that day forward, seeing the future before it happened we call deja vue is real. So I'm actually there is no heaven or hell that's a myth. Earth had many gods come teach us the future and every religion had that god sent to that location on earth. Every parts of the world has a different god but from then same origin like classmates. DMT made me see all of these things throughout my life and understand the real truth that lies around us but cults will always doubt you for blasphemy. We all die but we all live and eternal life is just not on the same planet. JWST has shown us some facts that the Bible can't explain cause the Bible is only made for the planet cause alien gods didn't think we would ever know the real truth about what God really are. Everyone on earth needs to do DMT once and you'll see.
@@Ryan-xq3kleveryone is ignorant here because microdosing has been proven to be a placebo
Another useful meditation lost due to the ignorance of the Government FDA / DEA which scheduled it as schedule 1 or no medical use, testing .
Correction, do to the greed and corruption of the FDA, which in the end is from ignorance because they don’t know that there is a God and that this God has a devil (enemy) on this earth that hates all that is good due to their choice to be evil.
@TrumpThreetimeswhy do bots always do weird punctuation like upside down question marks?
It isn't wrong 0:30 It's that in a Psychiatrist Brain this doesn't work... The brain have to work Normally for those activation patterns to show Physiologically... In people with Underdeveloped Prefrontal Cortex can have reward feedbacks from their brains for the most Deranged reasons: Hypnotising someone, a degree in psychiatry, raping a children, successfully convincing someone a Poisonous Neurotoxic substance can be a medicinal device. Is not that LSD doesn't activate Dopaminergic/Serotoninergic patterns... it's that in the hands of a particularly Dangerous individual as a Psychiatrist even an Aspirin can become Dangerous... Could be used as a Placebo for "threating" stage four cancer... In any case... Hoffmann Himself Explained LSD Functioning when He discovered it in 1935... It's not that the Psychiatric Regime is late.. It's the Gap between cognitive functions that brings to this Disparity of Knowledge.. That at the same Time can become an Antagonism to Knowledge itself...ergo Prohibitionism leading to: Scientific Negationism.. Which is what was Experienced during this last century of legalized academic madness... and LSD was a Minor scientific Loss Sincerely... Minor Crime to disregarding lisergic acid... Doesn't makes you a Genius...it increases Brain Sections Activation by Synaptic Receptors Membranes Stimulation in people who already have those fully Physiologically Developed.. Giving it to a Psychiatrist is lo like giving Rum to a 5 years old Child .. It ain't becoming Bukowski for sure... There is just a Greater Chance he will be Hurting Himself.. Now talking of Natural Psylocybine Usage in Rural Communities as Farmers and Rums... Instead... Now that is an interesting 'Field Study'
why isn't it legal then? democrat politicians are useless.
If we only lived in a world were we could ask millions of LSD users all around the globe which often took the drug for decades about their experiences... **sigh** But wait a moment... 😮 The day after my very first acid trip, many years ago, I immediately noticed that my craving for any kind of alcohol had almost completely vanished. And I actually had been a quite regular drinker of beer, wine, rum, whiskey and other stuff. This craving never came back! Yes, I am not a 'scientist'. But I am very sure, that millions of people who died from alcohol addiction since those days of shame, when one President Nixon declared total 'war on drugs', could have lived a much longer and healthier life, if 'science' had not shyed away from confronting the truth: that politics, racism and business alone have demonised and surpressed one of the most valuable therapeutic agents mankind has ever discovered.
The ability of "classic psychedelics" to help cure addictions has tons of anecdotal testimony. Plus I know of studies of ayahuasca specifically in the treatment of addiction. And there's a center called Takiwasi in Peru that has been using ayahuasca to treat cocaine addiction for over 20 years. I've also heard of studies of psilocybin used to help people stop smoking. And ibogaine is known to cure opiate addiction sometimes in a single session.
If that's what you call science then Bigfoot is real, scientifically.
@@treewalker1070 Plenty of anecdotes about people quitting drugs with no outside help whatsoever. So does doing literally nothing cure addiction? Cool, so we cured addiction then!?
@@treewalker1070strangly, is not only about addiction. I was not addicted to alcohol but... after starting using psychedelics I just feel that alcohol is harmful and just avoid it as much as I can.
I stopped cigarettes after being introduced to LSD. My life in general has changed for the better after LSD.
great info, thanks!
the problem with LSD has always been that it is so potent and powerful and the street doses were far too large.
Not if you want to trip. In the psychedelic scene here in the U.K. we have it as liquid so we can adjust the dose accurately. I get mine as concentrate at 500 mics per drop, and can adjust it to any strength using drops of high strength vodka - if I want a shamanic experience I’ll take 1500mics, if I want to microdose I’ll take 5-10mics
@@villhelm thanks for making my point clear. you obviously were not around in the 60's and 70's.
Personally i would say the street dosages during last 60’s -70’s was great.
@@jesternotclown i say that because they(high doses) gave the press and government all the reason they needed to vilify and outlaw the drug to the world. back in those days, one 'experience' would ruin one forever, so went the mythos. this microdose regime is very recent. we had to suffer Art Linkletter and Charlie Manson.
@@stephenmorton8017 But you also should mention that since LSD and magic mushrooms have no lethal dose, and are not addictive and don't harm the body, the american government and media created a campain of scaremongering with totally exaggerated and more often than not simply bogus news about those drugs - which the conservative middle aged majority of the public eagerly swallowed, while they were still in shock about their very own rebellious, long-haired, free loving, pacifist, anti-establisment children. None of those 'myths' that were created then have any grounding in facts or significant numbers of accidents etc. as everybody can easily find out if he is doing even minimal research work online today. But there have always been truths and facts that the public would rather not know because they damage their comfortable worldview and trigger primal fears. On the other hand: people then did not have the Internet and didn't have access to facts and data like we have nowadays - so it is even more annoying that still the majority of the people today believe the very same bs that was drummed into their parents. In my opinion and experience, there is no other subject in the world where the firm opinion of the vast majority of people, who mostly have no personal experience with it, is so far removed from the actual facts as with the subject of 'psychedelic drugs'. And that this even includes the majority of scientists and researchers that work in the field is totally laughable.
Sex video
Are those side effects on behavior only in humans or also in rodents?
Considering that 99% of the physiology works identically, one would expect the same effects in animal models.
Hi, keep up the work. You might enjoy this channel 👉 #drjohnaking. I find him instructional and practical.
how do you decide a thing or person is racist?
Hi, love the work. You might be interested in this channel 👉 #drjohnaking. I find him informative, yet down to earth.
Is neuropsychopharmacology a diffrent branch that someone can study and beacume a specialist in that specific area?
Hi, keep being a voice. You will enjoy this channel 👉 #drjohnaking. I find him instructional and practical.
Hi, keep up the work. You might enjoy this channel 👉 #drjohnaking. I find him informative, yet down to earth.
I've seen it increase depersonalization and derealization in certain people.
We already knew this was true from various human research trials, but now it's finally reached the bureaucratic front door!
^ this is scam
@@spitfire3311 What? Are you talking about?
Interesting
First time listening to NPP all info was explain well, looking forward to listening to more
You know stuff in life is serious when this very lecture is recommended to you.
Quiet kid gang unite
I have Autism AD HD OCD PDA 66 now it's a really struggle
𝐩𝓻Ỗ𝓂Ø𝓈M 💐
thnks a lot for introduce me in the neuroscineces I am psychologie and I am almost starting the next year my speciallity on Neurobiology and this blog is so scientific and trustworthy then I love it