Max Planck Institute of Molecular Physiology

Видео 6
Просмотров 8 324

The potential of cryo-electron tomography

2:38

Zooming in on muscle cells at the MPI Dortmund

7:15

International Max Planck Research School for Living Matter

6:55

3D arrangement of thin and thick filaments and the cross-bridges within a sarcomere.

0:24

Glovebox (CERES Clean Station) developed at the Max Planck Institute of Molecular Physiology

0:59

TomoTwin Interactive Clustering Tutorial

Demo of TomoTwin interactive clustering workflow in Napari for identifying and localizing protein molecules in cryoelectron tomograms de novo.
TomoTwin is a particle picking tool for cryoelectron tomograms based on deep metric learning. For more information:
GitHub: github.com/MPI-Dortmund/tomotwin-cryoet
ReadTheDocs: tomotwin-cryoet.readthedocs.io/en/stable/
Biorxiv: www.biorxiv.org/content/10.1101/2022.06.24.497279v1

Видео

The potential of cryo-electron tomography

2:38

The potential of cryo-electron tomography

Просмотров 1,3 тыс.2 года назад

The group of Stefan Raunser at the Max Planck Institute in Dortmund uses single particle cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) to study muscle contraction in health and disease. In particular, the scientists apply cryo-ET to understand how muscle proteins work within their cellular environment, i.e. the myofibril. Watch this video to see why they feel that cr...

Zooming in on muscle cells at the MPI Dortmund

7:15

Zooming in on muscle cells at the MPI Dortmund

Просмотров 1,2 тыс.3 года назад

Watch how an international team of scientists led by Prof. Stefan Raunser, director at the Max Planck Institute in Dortmund, has produced the first high-resolution 3D image of the sarcomere, the basic contractile unit of skeletal and heart muscle cells, by using electron cryo-tomography (cryo-ET). Get more information here: www.mpi-dortmund.mpg.de/news/zooming-in-on-muscle-cells

International Max Planck Research School for Living Matter

6:55

International Max Planck Research School for Living Matter

Просмотров 2,5 тыс.3 года назад

Innovative topics, the latest technologies, attractive working conditions and a philosophy that offers great scientific freedom - the IMPRS-LM offers an international, interdisciplinary, and modern PhD program for young scientists that are interested in dissecting the molecular, chemical and physical properties that characterize bio-molecular interactions. Get more information here: www.mpi-dor...

3D arrangement of thin and thick filaments and the cross-bridges within a sarcomere.

0:24

3D arrangement of thin and thick filaments and the cross-bridges within a sarcomere.

Просмотров 2,6 тыс.3 года назад

Tomogram of the sarcomere (Z-disc and I-bands) and 3D-reconstruction showing alpha-Actinin organisation between antiparallel thin filaments in the Z-disc. Recorded and developed by the group of Prof. Stefan Raunser at the Max Planck Institute of Molecular Physiology. Get more information in the Press Release - Zooming in on Muscle Cells www.mpi-dortmund.mpg.de/news/zooming-in-on-muscle-cells He...

Glovebox (CERES Clean Station) developed at the Max Planck Institute of Molecular Physiology

0:59

Glovebox (CERES Clean Station) developed at the Max Planck Institute of Molecular Physiology

Просмотров 1353 года назад

Sample preparation for Cryo-EM applications in glove box (CERES Clean Station) developed at the MPI. Glove box with cryo preparation station prevents ice contamination due to infinitesimal humidity. www.mpi-dortmund.mpg.de/news/new-cryo-tools-enter-market