GenScript USA Inc.
GenScript USA Inc.
  • Видео 386
  • Просмотров 951 821
Advancing Gene Editing Technologies with Spherical Nucleic Acids
Dr. Sergej Kudruk
International Institute for Nanotechnology (IIN) Postdoctoral Fellow, Northwestern University, Department of Chemistry
Nanomaterials have already begun to play a pivotal role in overcoming the limitations of traditional drugs by enhancing drug delivery, improving bioavailability, overcoming biological barriers in the treatment and prevention of diseases. Spherical Nucleic Acids (SNAs) stand out as a versatile class of nanomaterials that have been utilized in applications spanning diagnostics and therapeutics. SNAs, comprised of a nanoparticle core densely functionalized with radially oriented oligonucleotides, offer unique advantages for nanomedicine. Their 3-dimensional s...
Просмотров: 64

Видео

Autoimmune Diseases, the Arising Opportunities for Cell Therapies
Просмотров 3414 дней назад
Dr. Dong Geng VP, Head of Early-stage Drug Development Legend Biotech CAR-T cell therapies are now the established treatments for patients with relapsed and/or refractory B cell lymphomas, B cell acute lymphoblastic leukemia, and multiple myeloma. Through deep depletion of targeted malignancy cells, CD 19-targeted and BCMA-target CAR-T treatment could lead to long-term remissions, in some cases...
Synthetic biology approaches to improve cell therapy function
Просмотров 5014 дней назад
Dr. Michelle Hung Principal Scientist GeneFab There has been an explosion in the number of genetic medicines, including, cell & gene therapies in clinical development. These therapies contain thousands to billions more atoms than small molecules and biological drugs. Thus the design and manufacturing of these advanced therapies is much more complex than more established therapeutic modalities. ...
The Power of Automation: How Robotics Can Dramatically Reduce Cell Therapy Manufacturing Costs
Просмотров 8514 дней назад
Dr. Fred Parietti Co-founder and CEO of Multiply Labs There’s an elephant in the room when it comes to cell therapy. Hundreds of thousands of patients are in need of these life saving therapies - but the vast majority can’t access the treatment. This is because cell therapy manufacturing is reliant on a highly-skilled and limited labor pool, which results in prohibitively high prices and lack o...
Programmable Genomic Integration: a technology that enables the integration of large DNA sequences
Просмотров 7514 дней назад
Dr. Sandeep Kumar Senior Director, Platform Tome Biosciences Tome Biosciences is leading the field of programmable genomic integration (PGI). Building on founding technologies obtained from MIT and Replace Therapeutics, Tome has developed and refined PGI resulting in stable integration of multiple kilobases of DNA at user-defined locations. Integrase-mediated PGI (I-PGI) uses a Cas9 nickase wit...
Cytokine Armored CAR NK Cell Therapy for Advanced Ovarian Cancer
Просмотров 3714 дней назад
Dr. Branden Moriarity Associate Professor, Medical School, University of Minnesota Immunotherapy using chimeric antigen receptor (CAR) expressing NK cells engineered via viral vectors has shown exceptional efficacy against hematologic cancers in clinical trials. This method, however, is limited in cargo capacity and large-scale manufacturing for clinical use is cost-prohibitive to most academic...
De novo gene synthesis by an antiviral reverse transcriptase
Просмотров 14914 дней назад
Dr. Samuel Sternberg Associate Professor, Department of Biochemistry and Molecular Biophysics, Columbia University Bacteria defend themselves from viral infection using diverse immune systems, many of which sense and target foreign nucleic acids. Defense-associated reverse transcriptase (DRT) systems provide an intriguing counterpoint to this immune strategy by instead leveraging DNA synthesis,...
4th Annual Gene & Cell Engineering Virtual Summit Recap
Просмотров 52Месяц назад
Watch our recap of the event! Did you miss it or weren't able to attend the entire event? No worries! You can still register now and watch on demand: bit.ly/4cPC9f6
Accelerating Cell & Gene Therapy Success with cGMP Gene Editing Components and Regulatory Compliance
Просмотров 151Месяц назад
The manufacturing of gene editing (GE) components is a pivotal aspect of GE-based Cell and Gene Therapy development, requiring meticulous attention to product quality and regulatory compliance throughout the development lifecycle. In this webinar, we will discuss the key differences between GE components used from early discovery through to clinical application, and provide insight into how pha...
AI based Antibody Therapeutics Developability Assessment and Its Engineering
Просмотров 1912 месяца назад
Learn from an informative webinar about how AI-based platforms can facilitate the development process for antibody therapeutics and ensure candidates are not only therapeutically effective but also viable for large-scale production and clinical use. Monoclonal antibodies (mAbs) have become essential in treating a wide spectrum of diseases, with over 100 therapeutic antibody products now approve...
AET London 2024: Bispecific Antibody Therapeutics: Challenges, Opportunities and Future Directions
Просмотров 1112 месяца назад
This talk, “Bispecific Antibody Therapeutics: Challenges, Opportunities and Future Directions” was given during the 2024 Antibodies Engineering & Therapeutics Europe meeting in London, UK, by Robert Ford, PhD, Field Application Specialist at GenScript. In this presentation, you will learn about bi-specific antibodies (bsAbs) demonstrating novel functionalities that yield remarkable promise in i...
Streamlining Cell and Ex Vivo Gene Therapy Manufacturing Innovative Solutions from GenScript
Просмотров 1414 месяца назад
Cell and gene therapies are on the brink of transforming the pharmaceutical industry, presenting unique challenges such as ensuring the quality and consistent supply of reagents. Reagents play a crucial role in various stages of cell therapy development, from cell isolation and expansion to gene editing and characterization. Any inconsistency or variation in the quality of reagents can affect t...
Complete Toolbox for Gene Therapy Development with Live Q&A
Просмотров 984 месяца назад
Gene therapy has revolutionized the field of medicine, and it has the potential to cure a wide variety of genetic disorders. Gene therapy involves the introduction of a functional gene into the patient's cells to replace the missing or defective one. The two main technologies used for gene therapy are viral-based and non-viral gene editing. The primary advantage of viral-based gene editing is t...
Advanced Solutions for mRNA Vaccine Development with Live Q&A
Просмотров 1094 месяца назад
mRNA vaccines represent a pivotal innovation in prophylactic healthcare, offering a rapid response to emerging infectious diseases. Leveraging the cellular machinery to produce antigenic proteins, these vaccines induce robust immune responses without introducing live pathogens. Recent developments have focused on optimizing mRNA stability, delivery systems, and targeted immune activation. This ...
Bispecific Antibody Overview & Production with CrossMab Technology
Просмотров 7054 месяца назад
In this webinar, Dr. Sai Wang, protein senior scientist at GenScript Biotech Singapore, will discuss the advantages of bispecific antibodies (bsAbs), their mechanism of action (MOA), and the development history of bsAb platform. She will also help attendees to gain an understanding of the CrossMab production method and its significance in the field of antibody engineering. Additionally, Dr. Wan...
Advancing Brain Shuttle-Enabled Therapeutics for Efficient Delivery to CNS
Просмотров 2015 месяцев назад
Advancing Brain Shuttle-Enabled Therapeutics for Efficient Delivery to CNS
Life Science Research Grant Program
Просмотров 767 месяцев назад
Life Science Research Grant Program
Enhancing Treatments using Targeted Protein Degradation
Просмотров 2197 месяцев назад
Enhancing Treatments using Targeted Protein Degradation
The Future of Plasmid Maxi-prep is Here: AmMag™ Quatro Automated Solution
Просмотров 1868 месяцев назад
The Future of Plasmid Maxi-prep is Here: AmMag™ Quatro Automated Solution
Robust production of antibody fragments and their therapeutic applications
Просмотров 1868 месяцев назад
Robust production of antibody fragments and their therapeutic applications
PEGS Europe 2023: Empowering Therapeutic Antibody Development
Просмотров 848 месяцев назад
PEGS Europe 2023: Empowering Therapeutic Antibody Development
Bispecific Antibodies Structural Design, Production and Purification Strategies
Просмотров 1,3 тыс.8 месяцев назад
Bispecific Antibodies Structural Design, Production and Purification Strategies
Best in class antiviral antibodies from cognate recombinant antibody repertoires of human donors
Просмотров 509 месяцев назад
Best in class antiviral antibodies from cognate recombinant antibody repertoires of human donors
GenScript x XTalks Webinar: Adaptive Immune Response in Narcolepsy Type 1
Просмотров 10010 месяцев назад
GenScript x XTalks Webinar: Adaptive Immune Response in Narcolepsy Type 1
What to Expect from a CRO
Просмотров 12611 месяцев назад
What to Expect from a CRO
What to Expect from a CRO: What can you expect from GenScript once a project starts?
Просмотров 5111 месяцев назад
What to Expect from a CRO: What can you expect from GenScript once a project starts?
What to Expect from a CRO: How to establish a Contract for Services
Просмотров 3011 месяцев назад
What to Expect from a CRO: How to establish a Contract for Services
What to Expect from a CRO: How to start your Partnership with GenScript
Просмотров 3011 месяцев назад
What to Expect from a CRO: How to start your Partnership with GenScript
What to Expect from a CRO: Why start your partnership with GenScript?
Просмотров 2211 месяцев назад
What to Expect from a CRO: Why start your partnership with GenScript?
What to Expect from a CRO: The GenScript Experience
Просмотров 5311 месяцев назад
What to Expect from a CRO: The GenScript Experience