- Видео 27
- Просмотров 8 794
Mediana Online
США
Добавлен 13 янв 2022
Mediana LLC provides biostatistical consulting services and develops software tools to implement innovative trial designs and advanced statistical methods for clinical trials. This channel presents online training programs on key topics in clinical trial statistics and clinical trial simulation developed by Mediana. For more information on the company and its open-source software tools, see www.mediana.us and medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part II): Module D
Module D. General gatekeeping strategies (Gatekeeping strategies based on semiparametric procedures in multiplicity problems with general gatekeepers).
For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Просмотров: 266
Видео
Key Multiplicity Issues in Clinical Trials (Part II): Module E
Просмотров 1452 года назад
Module E. Group-sequential trials with multiple objectives (Introduction to group-sequential trials, Group-sequential trials with multiple endpoints). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part II): Module F
Просмотров 1102 года назад
Module F. General adaptive trials with multiple objectives (Decision rules in adaptive designs, Adaptive population selection trials). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part II): Module G
Просмотров 692 года назад
Module G. Power calculations in clinical trials with multiple objectives. For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part II): Module C
Просмотров 2322 года назад
Module C: Parallel gatekeeping strategies (Simple strategies based on nonparametric procedures, More powerful strategies based on semiparametric procedures in a parallel gatekeeping setting). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part II): Module B
Просмотров 2262 года назад
Module B: Introduction to gatekeeping strategies (General regulatory considerations, Classification of gatekeeping strategies, Analysis of secondary endpoints). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part II): Module A
Просмотров 912 года назад
Module A: Clinical trial examples (Phase III trials with multiple sources of multiplicity). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part II): Introduction
Просмотров 1912 года назад
For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part I): Introduction
Просмотров 6912 года назад
For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part I): Module B
Просмотров 2612 года назад
Module B: Key concepts: Inferential goals (at-least-one, all-or-none and global procedures), Error rate definitions, Classification of multiple testing procedures (single-step and stepwise procedures, nonparametric, semiparametric and parametric procedures). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part I): Module C
Просмотров 2182 года назад
Module C: Nonparametric and semiparametric multiple testing procedures I: Data-driven hypothesis ordering (Bonferroni, Holm, Hochberg and Hommel procedures). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part I): Module D
Просмотров 2562 года назад
Module D: Nonparametric multiple testing procedures II: Pre-specified hypothesis ordering (fixed-sequence, fallback and chain/graphical procedures). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part I): Module E
Просмотров 1032 года назад
Module E: Parametric multiple testing procedures (regular Dunnett and step-down Dunnett procedures). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part I): Module F
Просмотров 662 года назад
Module F: Simultaneous confidence intervals for commonly used multiple testing procedures (single-step and stepwise procedures). For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part I): Module G
Просмотров 832 года назад
Module G: Power calculations in clinical trials with multiple objectives. For more information on the software tools featured in this online training course, please visit medianasoft.github.io.
Key Multiplicity Issues in Clinical Trials (Part I): Module A
Просмотров 2432 года назад
Key Multiplicity Issues in Clinical Trials (Part I): Module A
Adaptive designs and clinical trial simulation (Part 10)
Просмотров 2772 года назад
Adaptive designs and clinical trial simulation (Part 10)
Adaptive designs and clinical trial simulation (Part 8)
Просмотров 1842 года назад
Adaptive designs and clinical trial simulation (Part 8)
Adaptive designs and clinical trial simulation (Part 6)
Просмотров 2842 года назад
Adaptive designs and clinical trial simulation (Part 6)
Adaptive designs and clinical trial simulation (Part 4)
Просмотров 3502 года назад
Adaptive designs and clinical trial simulation (Part 4)
Adaptive designs and clinical trial simulation (Part 9)
Просмотров 2132 года назад
Adaptive designs and clinical trial simulation (Part 9)
Adaptive designs and clinical trial simulation (Part 7)
Просмотров 2372 года назад
Adaptive designs and clinical trial simulation (Part 7)
Adaptive designs and clinical trial simulation (Part 5)
Просмотров 3752 года назад
Adaptive designs and clinical trial simulation (Part 5)
Adaptive designs and clinical trial simulation (Part 3)
Просмотров 4032 года назад
Adaptive designs and clinical trial simulation (Part 3)
Adaptive designs and clinical trial simulation (Part 2)
Просмотров 7062 года назад
Adaptive designs and clinical trial simulation (Part 2)
Adaptive designs and clinical trial simulation (Part 1)
Просмотров 1,9 тыс.2 года назад
Adaptive designs and clinical trial simulation (Part 1)
The procedure on slide 37 should be Holm rather than Hockberg
Slide 37 defines a truncated version of the Hochberg test. A truncated version of the Holm test can also be defined but the testing algorithm would begin with the smallest p-value in that case.
Thanks for uploading, great talk
Slide 5. Is the formula correct?
Thank you, it's a good catch, we will fix this typo (the sigma and delta need to be switched).
Great. God bless you all