Видео

what if a mismatch value is not given?

Great video, can you guide on how to filter our causative variant from gwas?

<:)

great explanation !

This was a really good video, but I have two questions: 1) In BLAST, it tries to find a local alignment, but, as I understand it, LASTZ is a global alignment, & in BLAST you can set for only the "best hit" but in a global alignment is this necessary? 2) Would you grant me permission to use timestamp: 08:39-14:26 to be used in an upcoming video on my channel? Thank you!

Finally what I was searching for. Best explanation after watching many videos. Thank you!!

thank you! I never really got the hang of dynamic programming in school, but this is clear enough that I get it now! you're a great teacher :)

Great explanation, thanks so much!

Do you know any software tool I can use to compare the results of full genome sequencing from two different companies? I have bought tests from Dante and Nebula, and once I get the results I would like to be able to compare them and do some statistical analysis of the differences. Thank you.

Best video I've watched so far on this topic, Thank you!

I have a question about the scoring, Do we say the score for the sequence at the end of your video is '-1' (i.e.) the score of the cell where we start tracing back, or do we say it's '+1', since there's a '+1' along the way. In simple words, are we considering the scores of the sub-sequences while scoring the sequence? P.S. I have a gut feeling we don't consider the scores of the sub-sequences, so the answer's '-1'. Tell me what you think.

This video helps me a lots. Thank you so much 💙

thanks you very much miss! It really helped

Greetings! I hope you are well. May I suggest considering enabling the automatic subtitles generated by RUclips for your video? They are currently deactivated and I believe they would be a valuable addition. Your video is enjoyed by many people from different countries, including some who may not be fluent in English. For instance, I stumbled upon your video through a link from my teacher. Sadly, some of my classmates who are non-English speakers are unable to understand it because the automatic subtitles are not available.

thank you so much

Can you make a video on space efficient sequence alignment problem as well or share any of your resources regarding that

oh my god, why am I paying my university when I could be paying you instead... Thank you so much for the glass-clear explanation!!!

This is great explanation but how did you even back track the path that part was not clear to me?

Ma'm you just saved my life. It was almost like my lecturer and you were explaining two completely different things. Thank you

Thank you

if question doesn't give the value of match how can i know that

at 13:39 why do we say the best thing to do is to match CC instead of mismatch C and T? You go from -2 to -3 instead of going from -2 to -2 which is maximal.

Thank you for this awesome explanation ❤

Nice quick simple video

Thanks for the explanation! I have a question regarding the path, when starting from the bottom right corner (-1), it came from -2, then -3. So, my question is could this -3 come from -4 as well (on diagonal as C-C is a match, (-4) + 1 = -3)? Then 0, and the rest keeps the same. In that case, besides the alignment result on the video, another possible alignment is ACGG-CTC to ATGGCCTC.

I'm an MSc student who has reviewed this concept a few times and this is by far the best explanation I have found, thank you so much

By french. C'est le loi de boison distribution binomiale statistique or dynamique. ( Just for 2 dimension). Donc, c'est le poison d' avril. Trĕtre!!!!!!! Apprendre les reseaux de neurones numerique. !!!!!!!

This is by far the best explanation !

great explanation

Thank you!!!

Thank you so much. I have one doubt, the example which we discussed are we using "Needleman-Wunsch algorithm" in here. i'm bit confused with words, Dynamic programming and Needleman. Could you please leave a comment on this.

Thank you شكراً

Great explanation, I just have 1 question: At 14:11 why is the gap on the horizontal sequence ( the vertical line) happens between the (-1) and (-3) on column 3 R to L? I’m confused because the gap can also happen between the last T and C (or vertical line between -2 and -2 on col 2 R to L) as well right?

I cant thank you enough. I literally understood this concept with your video. You are the best!

I've watched so many videos trying to understand this concept and this is the first one that actually explained it in a way I could understand without having to sit there for a half hour. I would be so lost without having watched this! Thank you so much!!!

Thank you so much! You explained better than most university professors

Thanks! It helped me a lot!

thank you ，swe e t y

try to breath enough :) you sound like you are out of breath all the time :) otherwise the explanation for global alignment

Great video. Short, sweet and to the point. Been trying to understand what makes these two methods different and keep finding confusing forums that get stuck talking about semantics.

Great help!

Nice! Better explained than our professor

This is the best video ever!!!!!!!!!!!!! Finally this makes sense, thank you so much for your time and efforts!

very good explanation

Thanks Deborah. My professor explained the same concepts and showed us an example in 4 hours and a half and the result was that no one understood anything. Your 15 minute video cleared everything up.

Great overview, thanks!

Nice Video. Thank you!

Fantastic video! Your explainations helped me to connect so many concepts. This was extremely helpful!

why in the right corner you picked gap -3 instead of mismatch -2? -2 is a smaller number than -3