- Видео 60
- Просмотров 88 767
Akoya Biosciences
США
Добавлен 28 янв 2019
As The Spatial Biology Company®, Akoya Biosciences’ mission is to bring context to the world of biology and human health through the power of spatial phenotyping. The company offers comprehensive single-cell imaging solutions that allow researchers to phenotype cells with spatial context and visualize how they organize and interact to influence disease progression and response to therapy. Akoya offers a full continuum of spatial phenotyping solutions to serve the diverse needs of researchers across discovery, translational and clinical research via its key platforms: PhenoCycler™, PhenoImager™ Fusion and PhenoImager HT. To learn more about Akoya, visit www.akoyabio.com.
Spatial Biology Speaker Panel
Peter Miller, Akoya’s vice president of research and development, guides the day’s speakers through a series of questions about their experiences working with RNA and spatial biology.
0:30 How do you see RNA data being useful in your work?
11:16 What are some of the issues that are limiting you in getting information out of the sample sets in your work?
20:27 What improvements in spatial imaging technology would be most valuable to you?
29:30 Where do you see proteomic profiling and spatial transcriptomics having the most benefit or utility, and how far along are we in realizing its potential?
0:30 How do you see RNA data being useful in your work?
11:16 What are some of the issues that are limiting you in getting information out of the sample sets in your work?
20:27 What improvements in spatial imaging technology would be most valuable to you?
29:30 Where do you see proteomic profiling and spatial transcriptomics having the most benefit or utility, and how far along are we in realizing its potential?
Просмотров: 80
Видео
Spatially Resolved Multi-omics Profiling Using DBiT-seq | Archibald Enninful | Yale University
Просмотров 923 месяца назад
Spatially resolved transcriptomics of tissue sections enables advances in fundamental and applied biomedical research, and the Fan Lab at Yale University developed microfluidic chips and the DBiT-seq (Deterministic Barcoding in Tissue) protocol to spatially encode mRNAs in various types of tissue. In this video, Archibald Enninful details how the team combined their transcriptome workflow with ...
Unveiling the TME in Pancreatic Cancer | Andressa Dias Costa, MD | Dana-Farber Cancer Institute
Просмотров 2353 месяца назад
Macrophages are one of the most common cell types in pancreatic cancer, but frustratingly for researchers and clinicians, measuring their overall density has shown little prognostic value. As a result, some pioneering scientists are turning to spatially resolved tissue analysis - which goes beyond simple cell density measurements to further describing the complex organization and relationship o...
Correlation of Multiplex Immunofluorescence with RNA Sequencing | Zhongmin Xiang, PhD | BostonGene
Просмотров 1793 месяца назад
From CODEX to the PhenoCycler-Fusion® 2.0, Zhongmin Xiang has seen the evolution of spatial biology technology first hand, and he is a big fan. In this video, the associate director of BostonGene describes how CROs use Akoya technology to provide a range of tumor and immunoprofiling services to their customers. Alongside stunning images, he shares some of the strategies his lab has developed, f...
Quantitative Multiplex Assays for Pan-Cancer Immuno-Oncology | Kathleen Pfaff, PhD | Dana-Farber
Просмотров 1333 месяца назад
Multiplex immunofluorescence (mIF) is a powerful way to quantify the immune cell densities within tumor samples, with a wide range of applications to improve our understanding of the biology of cancer, as well as to improve patient therapies. Could standard mIF assays make the technology even more accessible in the clinic? Principal scientist Kathleen Plaff talks about how the Tissue Biomarker ...
A Look Ahead on the Evolution of Spatial Biology | Peter Miller, PhD | Akoya Biosciences
Просмотров 2083 месяца назад
Spatial imaging has been embraced as an exquisite tool for looking at various aspects of cellular behavior and disease activity, but it’s still a very young technology. How did it go from ‘heroic experiment’ to a must-have tool for a wide range of applications in a variety of labs? Peter Miller, Akoya’s vice president of research and development, walks us through the evolution of single-cell sp...
Akoya Biosciences Operations and Manufacturing Center of Excellence
Просмотров 5103 месяца назад
Akoya is proud to announce the opening of our Operations and Manufacturing Center of Excellence in Marlborough, MA, to meet the growing demand for our spatial biology solutions and the increased utilization of our PhenoCycler®-Fusion and PhenoImager® HT platforms The 32,000ft² facility includes R&D, manufacturing, quality control, warehouse space, and distribution. Now fully operational, the pr...
Meet Spatial Biology 2.0 | Spatial Biology at YOUR Scale
Просмотров 65411 месяцев назад
Meet Spatial Biology 2.0 - Now, you can realize the true power of spatial biology, with studies conducted at unprecedented speed and scale. Whether unlocking breakthroughs from individual samples, generating spatial atlases on a human scale, understanding tumor heterogeneity, and identifying cellular neighborhoods or developing signatures at the population level, Spatial Biology 2.0 is poised t...
Introducing PhenoCode Discovery Panels
Просмотров 505Год назад
Introducing PhenoCode Discovery Panels-designed for the ever-expanding biomarker universe to advance cancer research. Researchers can simplify end-to-end workflows for spatial discoveries with ready-to-use panels, on the PhenoCycler-Fusion platform. What will you discover? bit.ly/3GS1TtJ
AGBT 2023 Flash Talk Presentation by Oliver Braubach, PhD
Просмотров 1,7 тыс.Год назад
Watch the recording from our AGBT 2023 Flash Talk presentation featuring Dr. Oliver Braubach from Akoya as he discusses high-speed multiomic spatial phenotyping of immunotherapy responses in head and neck cancer. View the poster here: bit.ly/3I4QqIp
Introducing PhenoCode™ Signature Panels
Просмотров 858Год назад
Whether you’re developing predictive biomarkers, understanding response to immunotherapy, developing the next generation of immunotherapies, or validating your biomarker studies, PhenoCode™ Signature Panels provides you the flexibility to keep pace with the dynamic combination therapy landscape. Explore panels: bit.ly/3A0qvNN
Data Analysis Solutions
Просмотров 6222 года назад
Learn about the available data analysis techniques giving researchers the chance to hear the stories our tissues are trying to tell us. It is these data that turn discoveries into actions.
PhenoCycler-Fusion Under the Hood
Просмотров 2,1 тыс.2 года назад
Learn about PhenoCycler-Fusion’s cutting edge fluidics control, fluorescent slide scanning, and optics. Learn more : www.akoyabio.com Follow Akoya Biosciences: Tweet with us on Twitter: Akoya Biosciences (@AkoyaBio) / Twitter Link with us on Linkedin: Akoya Biosciences, Inc. | LinkedIn
PhenoCycler-Fusion - Introducing a novel spatial multiomic solution
Просмотров 6072 года назад
Akoya Biosciences introduces a novel whole-slide spatial multiomics solution at single-cell resolution on the PCF system. This novel spatial transcriptomics solution will complement Akoya’s industry-leading spatial proteomics offering on the PhenoCycler-Fusion, providing users a powerful solution for whole-slide spatial multiomics Learn more at www.akoyabio.com/fusion
PhenoImager - Akoya’s patented multispectral imaging (MSI) technology
Просмотров 1,9 тыс.2 года назад
Learn more about challenges associated with multiplex imaging using immunofluorescence (mIF) and how Akoya Biosciences’ patented whole-slide multispectral imaging (MSI) multiplex solves for 2 key issues - tissue autofluorescence and spectral bleed through, providing accurate and quantitative data for spatial phenotyping applications including the development of highly predictive spatial phenoty...
Opal Multiplex and Simulated H&E on The Same Tissue Section
Просмотров 1,5 тыс.2 года назад
Opal Multiplex and Simulated H&E on The Same Tissue Section
Unlocking the Power of Spatial Biology Analysis
Просмотров 1,1 тыс.2 года назад
Unlocking the Power of Spatial Biology Analysis
A Spatial Biology Approach For Biomarker Discovery and Validation in Immuno-Oncology
Просмотров 5942 года назад
A Spatial Biology Approach For Biomarker Discovery and Validation in Immuno-Oncology
Spatial Biology Europe 2021 Broaching the next frontier of cellular identification with Single Cell
Просмотров 5512 года назад
Spatial Biology Europe 2021 Broaching the next frontier of cellular identification with Single Cell
T I M E and Space to Predict Response in Immuno Oncology
Просмотров 972 года назад
T I M E and Space to Predict Response in Immuno Oncology
Integrative Analysis of Single Cell Omics and Imaging Data
Просмотров 7172 года назад
Integrative Analysis of Single Cell Omics and Imaging Data
How Opal Multiplex Staining Can Accelerate Neuroscience Research
Просмотров 2442 года назад
How Opal Multiplex Staining Can Accelerate Neuroscience Research
Akoya’s Phenoptics™ and CODEX® Platforms for Multiplex Biomarker Visualization
Просмотров 2 тыс.2 года назад
Akoya’s Phenoptics™ and CODEX® Platforms for Multiplex Biomarker Visualization
How Autofluorescence Reduction can Improve Your CODEX Workflow
Просмотров 7202 года назад
How Autofluorescence Reduction can Improve Your CODEX Workflow
Evolution of Neuronal and Glial Tau Isoforms in Chronic Traumatic Encephalopathy CTE
Просмотров 2312 года назад
Evolution of Neuronal and Glial Tau Isoforms in Chronic Traumatic Encephalopathy CTE
European User Group Meeting 2020 Biomarker Research Focus
Просмотров 572 года назад
European User Group Meeting 2020 Biomarker Research Focus
Deep Learning and High Dimensional Analysis in Characterizing Drug Response
Просмотров 1212 года назад
Deep Learning and High Dimensional Analysis in Characterizing Drug Response
Spatial Proteomic Data with Parallel CITE seq Analysis Elucidates Multiomic Changes with Aging
Просмотров 2962 года назад
Spatial Proteomic Data with Parallel CITE seq Analysis Elucidates Multiomic Changes with Aging
If the panel is using a mic, just upload that audio channel! Like, are they eating the plates?!
If you think proteins are closer to determining phenotype than RNA, wait til you discover metabolomics. You just can’t really use fluorescence for small molecules. Oops @akoya
I wish the audio was a bit better than this.
Thank you for the helpful tutorial. Is there a way to access the tissue category areas, once you have only trained a tissue segmenter and only exported the tissue segmentation, without the cell segmentation?
But what are the software? Are they integrated in the Phenocycler Fusion, or are those third-party applications/packages? Thank you
😏 'promo sm'
A good presentation. But PLEASE invest in a better microphone!
Thank you so much for this amazing presentation and for explaining so well all the steps with examples!!!
You're very welcome!
Exciting stuff!
So dope.
The details description will be beneficial for us. Thank you
So dope.
Amazing.
Why rebranding?
Wonderful knowledge
Interesting
Hi i just wanted to ask whether other gypes than ffpe types of fixated tissues can be used with your kits. Can one also stain cells which were cultured in vitro and fixed with pfa??? Thanks a lot in advance.
Hi David, my understanding is that the denaturing procedure that us used to strip antibodies is going to kill many of the native epitopes, so in theory it's possible to use cells etc, but only if your antibodies are targeting epitopes that survive heating. Cheers - Nikolay Samusik, CEO Parhelia Bio