Gut
Gut
  • Видео 156
  • Просмотров 290 219
Crosstalk between immune cells controls liver regeneration after injury
To cite: Yang Y, Xu L, Atkins C, et al. Novel IL-4/HB-EGF-dependent crosstalk between eosinophils and macrophages controls liver regeneration after ischaemia and reperfusion injury. Gut 2024;73:1543-1553.
Read the full article here:doi.org/10.1136/gutjnl-2024-332033
Objective: Previous studies indicate that eosinophils are recruited into the allograft following orthotopic liver transplantation and protect from ischaemia reperfusion (IR) injury. In the current studies, we aim to explore whether their protective function could outlast during liver repair.
Conclusion: Together, these studies uncovered an indispensable role of eosinophils in liver repair after acute injury and identified a novel...
Просмотров: 9

Видео

Lactococcus lactis suppresses colorectal tumourigenesis and restores gut microbiota
Просмотров 6214 дней назад
To cite: Su ACY, Ding X, Lau HCH, et al. Lactococcus lactis HkyuLL 10 suppresses colorectal tumourigenesis and restores gut microbiota through its generated alpha-mannosidase. Gut 2024;73:1478-1488. Read the full article here:doi.org/10.1136/gutjnl-2023-330835 Objective: Probiotic Lactococcus lactis is known to confer health benefits to humans. Here, we aimed to investigate the role of L. lacti...
Visualising drug distribution in IBD
Просмотров 2921 день назад
To cite: Gabriëls RY, van der Waaij AM, Linssen MD, et al. Fluorescently labelled vedolizumab to visualise drug distribution and mucosal target cells in inflammatory bowel disease. Gut 2024;73:1454-1463. Read the full article here:doi.org/10.1136/gutjnl-2023-331696 Objective: Improving patient selection and development of biological therapies such as vedolizumab in IBD requires a thorough unde...
Panel identifies active eosinophilic oesophagitis
Просмотров 99Месяц назад
To cite: Gueguen E, Morsy Y, Mamie C, et al. Novel transcriptomic panel identifies histologically active eosinophilic oesophagitis. Gut 2024;73:1076-1086. Read the full article here:doi.org/10.1136/gutjnl-2023-331743 Objective: Eosinophilic oesophagitis (EoE) is characterised by symptoms of esophageal dysfunction and oesinophil tissue infiltration. The EoE Diagnostic Panel (EDP) can distinguish...
Fatty liver allele was fixed in Neanderthals
Просмотров 2182 месяца назад
To cite: Geier A, Trost J, Wang K, et al. PNPLA3 fatty liver allele was fixed in Neanderthals and segregates neutrally in humans. Gut 2024;73:1008-1014. Read the full article here:doi.org/10.1136/gutjnl-2023-331594 Objective: Fat deposition is modulated by environmental factors and genetic predisposition. Genome-wide association studies identified PNPLA3 p.I148M (rs738409) as a common variant t...
Association of healthy lifestyle behaviours with incident IBS
Просмотров 643 месяца назад
To cite: Ho FF, Sun H, Zheng H, et al. Association of healthy lifestyle behaviours with incident irritable bowel syndrome: a large population-based prospective cohort study. Gut 2024;73:922-931. Read the full article here:doi.org/10.1136/gutjnl-2023-331254 Objective: To evaluate the association between healthy lifestyle behaviours and the incidence of irritable bowel syndrome (IBS). Conclusion:...
Serum ferritin levels can predict long-term outcomes in MASLD
Просмотров 1453 месяца назад
To cite: Armandi A, Sanavia T, Younes R, et al. Serum ferritin levels can predict long-term outcomes in patients with metabolic dysfunction-associated steatotic liver disease. Gut 2024;73:825-834 Read the full article here: dx.doi.org/10.1136/gutjnl-2023-330815 Objective: Hyperferritinaemia is associated with liver fibrosis severity in patients with metabolic dysfunction-associated steatotic li...
Quantification of HBV RNA in patients with chronic hepatitis B
Просмотров 1273 месяца назад
To cite: Testoni B, Scholtès C, Plissonnier M, et al. Quantification of circulating HBV RNA expressed from intrahepatic cccDNA in untreated and NUC treated patients with chronic hepatitis B. Gut 2024;73:659-667. Read the full article here: dx.doi.org/10.1136/gutjnl-2023-330644 Objective: A convenient, reproducible biomarker of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) tran...
GLP1 agonists and risk of major adverse liver outcomes
Просмотров 964 месяца назад
To cite: Wester A, Shang Y, Toresson Grip E, et al. Glucagon-like peptide-1 receptor agonists and risk of major adverse liver outcomes in patients with chronic liver disease and type 2 diabetes. Gut 2024;73:835-843. Read the full article here: dx.doi.org/10.1136/gutjnl-2023-330962 Objective: Phase II trials suggest glucagon-like peptide-1 receptor (GLP1) agonists resolve metabolic dysfunction-a...
Early-life diet and risk of IBD
Просмотров 1105 месяцев назад
To cite: Guo A, Ludvigsson J, Brantsæter AL, et al. Early-life diet and risk of inflammatory bowel disease: a pooled study in two Scandinavian birth cohorts. Gut 2024;73:590-600. Read the full article here: dx.doi.org/10.1136/gutjnl-2023-330971 Objective: We assessed whether early-life diet quality and food intake frequencies were associated with subsequent IBD. Conclusion: In this Scandinavian...
Specific gut pathobionts escape antibody coating in patients with severe Crohn’s disease
Просмотров 1316 месяцев назад
To cite: Eriksen C, Danneskiold-Samsøe NB, Moll JM, et al. Specific gut pathobionts escape antibody coating and are enriched during flares in patients with severe Crohn’s disease. Gut 2024;73:448-458. Read the full article here: dx.doi.org/10.1136/gutjnl-2023-330677 Objective: Patients with Crohn’s disease (CD) exhibit great heterogeneity in disease presentation and treatment responses, where d...
Lactobacillus gallinarum-derived metabolites boost anti-PD1 efficacy in colorectal cancer
Просмотров 2849 месяцев назад
To cite: Fong W, Li Q, Ji F, et al. Lactobacillus gallinarum-derived metabolites boost anti-PD1 efficacy in colorectal cancer by inhibiting regulatory T cells through modulating IDO1/Kyn/AHR axis. Gut 2023;72:2272-2285. Read the full article here: dx.doi.org/10.1136/gutjnl-2023-329543 Objectives: Gut microbiota is a key player in dictating immunotherapy response. We aimed to explore the immunom...
Eradicating Helicobacter pylori via 13C-urea breath screening in indigenous communities
Просмотров 1939 месяцев назад
To cite: Lei W, Lee J, Chuang S, et al. Eradicating Helicobacter pylori via 13C-urea breath screening to prevent gastric cancer in indigenous communities: a population-based study and development of a family index-case method. Gut Published Online First: 17 May 2023. doi: 10.1136/gutjnl-2023-329871. Read the full article here: dx.doi.org/10.1136/gutjnl-2023-329871 Objectives: Screening and erad...
Morphology-based gross classification system for HCC stratification
Просмотров 1069 месяцев назад
To cite: Fan Z, Jin M, Zhang L, et al. From clinical variables to multiomics analysis: a margin morphology-based gross classification system for hepatocellular carcinoma stratification. Gut 2023;72:2149-2163. Read the full article here: dx.doi.org/10.1136/gutjnl-2023-330461 Objectives: Selecting interventions for patients with solitary hepatocellular carcinoma (HCC) remains a challenge. Despite...
Gut virome is associated with ulcerative colitis pathogenesis
Просмотров 14310 месяцев назад
To cite: Massimino L, Palmieri O, Facoetti A, et al. Gut virome-colonising Orthohepadnavirus genus is associated with ulcerative colitis pathogenesis and induces intestinal inflammation in vivo. Gut 2023;72:1838-1847. Read the full article here: dx.doi.org/10.1136/gutjnl-2022-328375 Objectives: Ulcerative colitis (UC) is a chronic inflammatory disorder of unknown aetiology. Gut virome dysbiosis...
Molecular phenotyping of ARID1A-deficient gastric cancer reveals therapeutic opportunities
Просмотров 13811 месяцев назад
Molecular phenotyping of ARID1A-deficient gastric cancer reveals therapeutic opportunities
Age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP
Просмотров 27611 месяцев назад
Age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP
Immune and barrier dysfunction-related proteomic signatures in Crohn’s disease
Просмотров 171Год назад
Immune and barrier dysfunction-related proteomic signatures in Crohn’s disease
Sympathetic nervous activation, mitochondrial dysfunction and outcome in decompensated cirrhosis
Просмотров 115Год назад
Sympathetic nervous activation, mitochondrial dysfunction and outcome in decompensated cirrhosis
Fungi and cancer
Просмотров 440Год назад
Fungi and cancer
Gut microbiota influence anastomotic healing in colorectal cancer surgery
Просмотров 375Год назад
Gut microbiota influence anastomotic healing in colorectal cancer surgery
Severity of gastric intestinal metaplasia predicts the risk of gastric cancer
Просмотров 3,4 тыс.Год назад
Severity of gastric intestinal metaplasia predicts the risk of gastric cancer
Rewiring tryptophan metabolism in IBD
Просмотров 444Год назад
Rewiring tryptophan metabolism in IBD
Vitamin D receptor governs oesophageal epithelial barrier responses
Просмотров 326Год назад
Vitamin D receptor governs oesophageal epithelial barrier responses
Epithelial RAC1-dependent dynamics in intestinal inflammation
Просмотров 385Год назад
Epithelial RAC1-dependent dynamics in intestinal inflammation
Inflamed and non-inflamed classes of HCC
Просмотров 152Год назад
Inflamed and non-inflamed classes of HCC
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity
Просмотров 221Год назад
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity
Smoking promotes colorectal cancer via the gut microbiota
Просмотров 249Год назад
Smoking promotes colorectal cancer via the gut microbiota
Discovery and 3D imaging of a novel basal cell type in human pancreatic ducts
Просмотров 170Год назад
Discovery and 3D imaging of a novel basal cell type in human pancreatic ducts
Lactobacillus gallinarum, gut microbiota and anti-cancer metabolites
Просмотров 913Год назад
Lactobacillus gallinarum, gut microbiota and anti-cancer metabolites

Комментарии

  • @RONALDREAGENTS
    @RONALDREAGENTS 5 часов назад

    Make love to me

  • @barbarapriego8752
    @barbarapriego8752 15 дней назад

    En español,sería perfecto para seguir ya que no entiendo ingles,sorri,gracias me parece muy interesante

  • @JackieAnnebarris
    @JackieAnnebarris 22 дня назад

    Thank you ladies for your presentation...I understood you completely! You ll are simply gorgeous and beautiful KEEP UP the OUTSTANDING PRESTATION and the NEXT ONE will be even better. Love Live Lite to Your Spirit Heart and Soul ⬆️🌬️ honesty honestly honest ☺️🥰😍🤩😘

  • @debbiegoble9836
    @debbiegoble9836 23 дня назад

    Can't understand you.

  • @gustavojaradiaz2236
    @gustavojaradiaz2236 29 дней назад

    ke es candidiasis

  • @nas0075
    @nas0075 Месяц назад

    If I understand this correctly. Having an Side Branch IPMN greater than 30mm, although a worrying feature, is not enough to warrant surgery? I have a 37mm x 27mm side branch IPMN in the head and only other worrying feature beside the size, is possible wall thickening.

  • @peapod8
    @peapod8 2 месяца назад

    Missed a lot due to thick accents. Medical terms should be spelled out on screen with call-outs.

  • @charlottehauptfleisch5806
    @charlottehauptfleisch5806 2 месяца назад

    This is a beautiful presentation. Your passion shine in your research. For me as a layman it was above my understanding and comprehension. I wish I could understand more. That said I can see that this research must be interesting and fascinating.

  • @deborahmuniz3724
    @deborahmuniz3724 3 месяца назад

    I feel carpets with fibers should be banned unexceptable in apartment homes , get rid of all kinds of mite's and germs, especially in hot climate conditions.

  • @carolmoccia6332
    @carolmoccia6332 3 месяца назад

    All my sisters doctors told her for 15 years she only had ibs but guess what she did not have ibs she passed away at age 26 yrs old of colon cancer I miss her so much 😢 there needs to be more different tests to prove 100 percent that a person has ibs for sure.

  • @BuggsSunny
    @BuggsSunny 6 месяцев назад

    - Research Focus: Dr. Moreau leads a team studying immune regulation in Valley River high, focusing on the mechanism of gut immune regulation in both infants and adults. - Hypothesis: The team hypothesizes that a specific antigen, house dust mite (HDM), may be present in the human gut, contributing to diseases associated with skin barrier dysfunction. - Study Design: Collaborating with researchers in translational immunology and gastroenterology, the team sampled six gut regions, finding that HDM is indeed present, with concentrations decreasing from the duodenum to the rectum. - Permeability Investigation: The study examines the impact of HDM on gut permeability, showing increased permeability with higher HDM concentrations, affecting tight junction integrity. - ‍ Enzyme Inhibition: Inhibiting serine and cysteine protease activity shows that cysteine proteases are responsible for the increased responses to HDM. - Allergic Sensitization: Contrary to expectations, both allergic and non-allergic subjects respond to HDM exposure, suggesting that prior sensitization is not necessary. - Impact on Gut Barrier: In patients with irritable bowel syndrome (IBS), gut permeability is further compromised following HDM exposure compared to control subjects. - Inflammatory Response: While HDM primarily induces a non-inflammatory response in healthy individuals, IBS patients show a predominantly pro-inflammatory response, driven by TNF. - Conclusion: The study implies that HDM exposure, particularly from house dust mites, can impact gut health, potentially acting as an environmental trigger for inflammatory diseases. This opens avenues for epidemiological studies and suggests considering cysteine protease targeting for therapy and controlling respiratory allergen exposure for IBS treatment

  • @ellemason2055
    @ellemason2055 6 месяцев назад

    So, in human level vs invitro/invivo , caffeine is NOT really effective because of the neurotoxicity? Has there been any progress in creating that safer medicinal template out of the results from invtro/invivo tests? Something that will be safe for humans?

  • @ellemason2055
    @ellemason2055 6 месяцев назад

    Thank you for this information ❤ how much coffee is ideal for preventing pancreatic issues?

  • @user-rh6cn8lz5q
    @user-rh6cn8lz5q 7 месяцев назад

    Wi la melesiya❤❤❤❤

  • @ohzone6464
    @ohzone6464 7 месяцев назад

    "dustmite allergens{" FACE IT you have Candida. See reseach.

  • @supercaptainbatdoggy
    @supercaptainbatdoggy 7 месяцев назад

    If dust mites get in the gut, can they produce inflammation which mimics flares of chrons disease??

  • @DANIGOSA_
    @DANIGOSA_ 8 месяцев назад

    Que pena que no lo traduzcan, parece interesante

  • @marjorievandamme4399
    @marjorievandamme4399 8 месяцев назад

    What treatment does dust mites have in the scalp in Australia nothing shown

  • @drrakeshkumar6917
    @drrakeshkumar6917 8 месяцев назад

    Door mats and kalins have lot if dust mites . Dust mites and Cockroaches are common causes of respiratory, dermal( skin ) and gut allergic inflammation. Prevention of these by reducing exposure is the important.

  • @philomenawama2199
    @philomenawama2199 9 месяцев назад

    Coffee is a food drink God created to fix our body, just dont over do it. 2 cups a day heals the body naturally. If it was bad then God would have not created it. How can a father poison his own child? So let us as humanbeings use our common sense and use it rightly and get the desired results. So yes coffee is good, caffeine is good in the right amounts.

  • @mattharvey8712
    @mattharvey8712 11 месяцев назад

    Bravo.........ist not a mite..........worms.......de worm .....u get from un cooked meats ...fish....pork....that one eats brain ...dont trust me......cheers

  • @sentimentalsoldier5837
    @sentimentalsoldier5837 11 месяцев назад

    The captions for this video are so off! It's hard to hear what they are saying in English because of the accents and the closed captions are no where near what is being said.

    • @amykat75
      @amykat75 7 месяцев назад

      Same here. I understood basically nothing. I only got that there might be a link between IBS and dust mites.

  • @hjpapow
    @hjpapow 11 месяцев назад

    The music makes this video unwatchable.😞😮‍💨 I'll find the information elsewhere, I guess.

  • @arpitpunetha7810
    @arpitpunetha7810 Год назад

    For how long is it to be given? If the patient is in remission

  • @abdoale107
    @abdoale107 Год назад

    Very nice doctor

  • @Macen121487
    @Macen121487 Год назад

    Umm, what?

  • @kerrybutler5172
    @kerrybutler5172 Год назад

    English please

  • @vincentmack6177
    @vincentmack6177 Год назад

    i can barley hear him the audio is not good

  • @AmruteshPuranik
    @AmruteshPuranik Год назад

    Nice work!

  • @vicguani2108
    @vicguani2108 Год назад

    GOD bless 😊

  • @Kru5hit
    @Kru5hit Год назад

    How do you get this test done?

  • @user-lj8qk6gw2l
    @user-lj8qk6gw2l Год назад

    And in Germany now they have it on the banned list after 5 years.

  • @drgeraldrapp
    @drgeraldrapp Год назад

    ruclips.net/video/y0OUjJQi6c0/видео.html - HDM DESTROYED MINE - the secondary systemic pathology is understudied, and mismanaged.

  • @vadpachi1093
    @vadpachi1093 Год назад

    100% correct that dust mites cause the problem of gut...

  • @karaschmidtify
    @karaschmidtify Год назад

    What is a resolvin. What drug is being used here. Need help

    • @stokesrealestate
      @stokesrealestate Год назад

      Found in omega 3 fatty acids like fish oil

    • @jmc8076
      @jmc8076 8 месяцев назад

      Google it lots of info.

  • @avm2071
    @avm2071 Год назад

    what is the treatment please

  • @kisigma1011
    @kisigma1011 Год назад

    this is very true when I move in a broken apartment full of dust it messed up my immune system bad no matter how I clean the apartment it attract dust like nothing also no matter what I eat even clean eating and water fast I end up gaining weight like nothing.

  • @jackd.ripper3139
    @jackd.ripper3139 2 года назад

    But….you offer no treatment for ppl who suffer from it 🧐😢🙄‼️

  • @snowyowl6892
    @snowyowl6892 2 года назад

    Irritating, jittery, ghastly music. It is not necessary. The difficult accent takes 100% highly focused attention - we don’t need the extra irritation of the “music”.

  • @aaronlina8794
    @aaronlina8794 2 года назад

    Coming across Dr Igudia on RUclips was indeed the greatest thing that has ever happened to me after using his natural herbs medication to cure my Hepatitis B Virus

  • @l.summer170
    @l.summer170 2 года назад

    Interesting video. I too have digestive issues & severe dust mite allergies. If i understand this video correctly....you're saying one probably caused the other. Ok.

  • @bubbamanandkids2974
    @bubbamanandkids2974 2 года назад

    When you wanna sound smart and not use real words for real people-- be these guys

  • @allahrasgulla7603
    @allahrasgulla7603 2 года назад

    Dust mites cause, allergic rhinitis,IBS,leaky gut syndrome.... which predispose to autoimmune condition,like hashimotos thyroiditis, rheumatoid arthritis,...bla,bla.....

  • @About36Greekss
    @About36Greekss 2 года назад

    This disease aswell as many others are caused by Gut dysbiosis period

  • @satuba2738
    @satuba2738 2 года назад

    Hi, I used 3rd generation oral cephalosporins and got prone to dust allergy severely and had an overall decline of my body energy level. The disturbance of gut flora leads to unidentified truths. Gut health is really important and so to limit the extensive use and prescription of broad spectrum antibiotics.

  • @JohnDoe-nd6rt
    @JohnDoe-nd6rt 2 года назад

    You can obviously see that this is being put into the stuff that we consume intentionally. It causes reproductive harm as well as disturbing effects on the body.

  • @gopalahir1942
    @gopalahir1942 2 года назад

    Sir my colonoscopy endoscopy ct scan mr entrography fecal calprotectin normal but I have so many problems I have pain in abdomen and I have problem in eating and my weight loss 25 kg 70 to 45 please guide me what to do

  • @baradonna9205
    @baradonna9205 2 года назад

    Very much tutorial. Thank you

  • @roken441
    @roken441 2 года назад

    I've cancer from prolonged PPI usage

  • @BELINC7
    @BELINC7 2 года назад

    Did not understand anything and did not learn anything. I hope the 3 scientists who heard it learned something.